Sentences with phrase «neurological diseases of aging»

BIIB054 was originally developed by biotech company Neurimmune, using a platform they call Reverse Translational Medicine (RTM ®), which derives therapeutic antibody candidates from libraries of de-identified B - cells isolated from ostensibly healthy older adults (those free of specific neurological diseases of aging).

Albany Medical Center's Alzheimer's Center Director Dr. Earl Zimmerman joins Alan in the studio to discuss Alzheimers, dementia, and other neurological diseases of aging.

Not exact matches

Scientific studies have shown that consumption of cranberries have potential health benefits against cancer, aging and neurological diseases, inflammation, diabetes, and bacterial infections.

Dr. Saper's research has explored circuitry of the brain that controls basic functions such as wake - sleep cycles, feeding, and immune response, and how these circuits are disrupted in neurological disorders, such as Parkinson's disease, in sleep disorders such as narcolepsy and sleep apnea, and during aging.

Each of them had been diagnosed before the age of 18 and had had the relapsing - remitting form of MS or clinically isolated syndrome, which describes the first episode of neurological symptoms associated with the disease, for under four years.

The scientists compared that tissue with brain tissue samples from three young amateur American football players and a professional wrestler, all of whom had a history of repetitive concussive injury, and with four samples from comparably aged control subjects with no history of blast exposure, concussive injury or neurological disease.

However, although people are living longer, they are not necessarily healthier than before — nearly a quarter (23 %) of the overall global burden of death and illness is in people aged over 60, and much of this burden is attributable to long - term illness caused by diseases such as cancer, chronic respiratory diseases, heart disease, musculoskeletal diseases (such as arthritis and osteoporosis), and mental and neurological disorders.

Barnes is the primary author and director of the Rush Center of Excellence on Disparities in HIV and Aging in the Rush Alzheimer's Disease Center, and professor of Neurological Sciences and Behavioral Sciences at Rush University Medical Center.

«We tried to untangle the large role aging appears to play in some of the most devastating neurological disorders,» said Edward Giniger, Ph.D., senior investigator at the NIH's National Institute of Neurological Disorders and Stroke and the senior author of the study published in Disease Models &neurological disorders,» said Edward Giniger, Ph.D., senior investigator at the NIH's National Institute of Neurological Disorders and Stroke and the senior author of the study published in Disease Models &Neurological Disorders and Stroke and the senior author of the study published in Disease Models & Mechanisms.

Researchers from Kent State University's College of Arts and Sciences, along with colleagues from the George Washington University, Yerkes National Primate Research Center, Georgia State University, Barrow Neurological Institute and the Icahn School of Medicine at Mount Sinai, found that the brains of aged chimpanzees, our closest living relatives, show pathology similar to the human Alzheimer's disease brain.

HD is a fatal, inherited neurological disease that usually manifests between 30 and 50 years of age.

«It is our hope that these results may usher in new age of cost - effective, MAbs therapeutics against WNV and other neurological diseases,» said Chen.

In a mouse model of late infantile neuronal ceroid lipofuscinosis (NCL), a pediatric neurological disease, the researchers described retinal degenerative changes that mimic the characteristic pathology of age - related macular degeneration (AMD).

Yet one - third of global health issues are related to neurological problems, such as depression, pain, and the diseases of the aging brain.

His research is based on the concept that normal brain aging and the pathogeneses of sporadic neurological diseases are not a consequence of a few single or «disease - specific «factors alone, rather they are driven by holistic events that include one's individual genetic and epigenetic condition, progression of aging, and lifestyle.

The findings, published today in the online journal PloS One, open new opportunities for gaining a greater understanding of Alzheimer's disease and other neurological diseases and for developing therapies to halt its progression, according to senior author Karen E. Duff, PhD, professor of pathology (in psychiatry and in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain) at CUMC and at the New York State Psychiatric Insdisease and other neurological diseases and for developing therapies to halt its progression, according to senior author Karen E. Duff, PhD, professor of pathology (in psychiatry and in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain) at CUMC and at the New York State Psychiatric InsDisease and the Aging Brain) at CUMC and at the New York State Psychiatric Institute.

Funding was provided by the National Institute of Neurological Disorders and Stroke, Taube / Koret Center for Neurodegenerative Disease, Hellman Family Foundation Alzheimer's Disease Research Program, UCSF Medical Scientist Training Program, Hereditary Diseae Foundation, CHDI Foundation, and the National Institute on Aging.

In addition, neuronal damage and death are key features of the pathophysiology of age - related neurological diseases including Alzheimer's and Parkinson's disease.

Support for this research was provided by a Ruth L. Kirschstein Fellowship, the National Institute of Neurological Disease and Stroke, the National Institute on Aging and the Keck Foundation.

In further testing, BIIB054 selectively bound aggregated AS in tissue samples from people with PD and with Dementia with Lewy Bodies (DLB — a related disease of AS - driven neurological aging), while leaving native AS alone.

Gladstone Investigator Ken Nakamura, MD, PhD, and the National Institutes of Health Investigator Mark Cookson, PhD, also participated in this research, which was supported by the following: the de Clercq Family, the National Center for Research Resources (#RR189288), the Burroughs - Wellcome Medical Scientist Fund, the National Institute of Neurological Disorders and Stroke (#P30NS069496), the National Institute on Aging, the Taube - Koret Center for Huntington's Disease Research, the Hellman Family Foundation, the California Institute for Regenerative Medicine (#RB4 -06079) and the National Institutes of Health (#U24 NS078370, # 3R01 NS039074, # 2R01 NS04549).

Believed to be one of the primary actors in the aging process, free radicals are also implicated in numerous age - related diseases, including cancer, heart disease, stroke, and many neurological disorders.

«Although FTD and NCL patients differ markedly in age and clinical manifestations, we wanted to know if humans who carry FTD - related genetic mutations in progranulin share features with NCL patients,» said Li Gan, PhD, associate director of the Gladstone Institute of Neurological Disease and professor of neurology at UCSF.

CMBN shall take on a leading role in elucidating the role of DNA repair and genome maintenance mechanisms in preventing neurological disease and brain ageing.

Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases.

Our research aims at identifying the principles of neuronal interactions with signals from the cellular microenvironment and uncovering disease - relevant targets that can be harnessed to drive drug discovery efforts in neurological and age - related neurodegenerative diseases.

The Centre shall take on a leading role in elucidating the role of DNA repair and genome maintenance mechanisms in preventing neurological disease and brain ageing.

«We need to understand the impact of factors that complicate recovery of function from neurological diseases, including fatigue, immobilization, aging and cognitive deficits,» Dr. Yue noted.

To elucidate the roles of neuronal signaling mechanisms in ageing and neurological disease, including neurodegenerative and ischemic disorders, epilepsy, and memory disorders.

It also helps the aging, those burdened with physical challenges such as Multiple Sclerosis or Parkinson's disease, and it can help our younger generation manage the symptoms of neurological disorders.

Being diagnosed with a «progressive and incurable» neurological disease at the age of 23 has been my greatest burden but also my greatest gift because of the juicy life lessons I have learned through the daily and sometimes menacing struggles of living with, treating and healing from a debilitating and disabling disease.

The numbers of neurons in our brains begin to decrease at the age of thirty and some neurological diseases can result from significant loss.

The scientists, medical professionals, and athletes on the ground floor of the keto movement can barely contain their excitement over its power to reliably reduce excess body fat, enhance neurological function, protect against diseases of cognitive decline, and slow the rate of inflammation and oxidative damage that are the essence of the (accelerated) aging process.

Epilepsy is classed as one of the most common neurological diseases as it affects 50 million people worldwide, occurring at any age.

Eating glucose will raise insulin and raise leptin, will impede the ability to burn fat, and contribute in some degree to progressive insulin and leptin resistance that is a hallmark of accelerated aging and its associated symptoms of cardiovascular disease, diabetes, obesity, osteoporosis, immunity disorders, brain and neurological diseases, and cancer.

A key ingredient in the leaf called oleuropein, decreases the symptoms and occurrence of neurological age - related conditions such as dementia and Alzheimer's disease.

Researchers have found that BDNF levels decline progressively with age.10 Lommatzsch, M., et al. «The Impact of Age, Weight and Gender on BDNF Levels in Human Platelets and Plasma,» Neurobiology of Aging 26 (2005):... continue At the same time that BDNF levels decrease, the volume of the hippocampus (primary center for emotion and memory) also decreases.11 Erickson, K.L., et al. «Brain - Derived Neurotrophic Factor is Associated with Age - Related Decline in Hippocampal Volume, Journal of Neuroscience 30,... continue In fact, in some neurological diseases, such as Huntington's and Alzheimer's disease, BDNF levels are low or deficient.12 Laske, C., et al. «Decreased Brain - Derived Neurotrophic Factor (BDNF) and B - Thromboglobulin Blood Levels in Alzheimer's Disease,» Journal of... contiage.10 Lommatzsch, M., et al. «The Impact of Age, Weight and Gender on BDNF Levels in Human Platelets and Plasma,» Neurobiology of Aging 26 (2005):... continue At the same time that BDNF levels decrease, the volume of the hippocampus (primary center for emotion and memory) also decreases.11 Erickson, K.L., et al. «Brain - Derived Neurotrophic Factor is Associated with Age - Related Decline in Hippocampal Volume, Journal of Neuroscience 30,... continue In fact, in some neurological diseases, such as Huntington's and Alzheimer's disease, BDNF levels are low or deficient.12 Laske, C., et al. «Decreased Brain - Derived Neurotrophic Factor (BDNF) and B - Thromboglobulin Blood Levels in Alzheimer's Disease,» Journal of... contiAge, Weight and Gender on BDNF Levels in Human Platelets and Plasma,» Neurobiology of Aging 26 (2005):... continue At the same time that BDNF levels decrease, the volume of the hippocampus (primary center for emotion and memory) also decreases.11 Erickson, K.L., et al. «Brain - Derived Neurotrophic Factor is Associated with Age - Related Decline in Hippocampal Volume, Journal of Neuroscience 30,... continue In fact, in some neurological diseases, such as Huntington's and Alzheimer's disease, BDNF levels are low or deficient.12 Laske, C., et al. «Decreased Brain - Derived Neurotrophic Factor (BDNF) and B - Thromboglobulin Blood Levels in Alzheimer's Disease,» Journal of... contiAge - Related Decline in Hippocampal Volume, Journal of Neuroscience 30,... continue In fact, in some neurological diseases, such as Huntington's and Alzheimer's disease, BDNF levels are low or deficient.12 Laske, C., et al. «Decreased Brain - Derived Neurotrophic Factor (BDNF) and B - Thromboglobulin Blood Levels in Alzheimer's Disease,» Journal of... cdisease, BDNF levels are low or deficient.12 Laske, C., et al. «Decreased Brain - Derived Neurotrophic Factor (BDNF) and B - Thromboglobulin Blood Levels in Alzheimer's Disease,» Journal of... cDisease,» Journal of... continue

We know that free radicals (damaged atoms) cause all kind of health problems including cancer, fatigue, weak immune system, ageing, neurological problems, poor memory, chronic diseases, etc..

Toxins make us age faster and increase our risk for cancer, autoimmune diseases, inflammation, liver and kidney problems, Alzheimer's and Parkinson's disease and all sorts of other neurological problems.

Antioxidants help guard against a range of cancers, heart disease, asthma, arthritis and cataracts, Alzheimer's and age - related neurological diseases.

Eligibility was determined through the following inclusion criteria: 1) age range of 13 — 20 y; 2) overweight to obese (BMI: 25 — 34.9 kg / m2); 3) no metabolic or neurological diseases or other health complications; 4) no clinical diagnosis of an eating disorder; 5) not currently or previously on a weight loss or other special diet in the past 6 months; 6) documented regular menstrual cycles between 21 — 36 days in duration for the past 6 months; and 7) infrequent breakfast consumer (i.e., ≤ 2 breakfast occasions / wk).

The signs that I have related to you are also the signs one would see if the pet had age - related neurological disease of the spinal cord and disks.

Seizure - free dogs that died before age four were not included in the data analysis and 37 dogs that had seizures in the presence of seizure - associated conditions or diseases, such as hyperthermia, portosystemic shunts, head trauma, or brain / neurological lesions, such as neoplasia and ehrlichiosis, were excluded from the study.

A number of medical issues - including a urinary tract infection, a weak sphincter caused by old age, hormone - related problems after spay surgery, bladder stones, diabetes, kidney disease, Cushing's disease, neurological problems and abnormalities of the genitalia - can cause urinary incontinence in dogs.

The prognosis for dogs with distemper depends upon how quickly the disease is diagnosed, the dog's vaccination status and overall health, whether neurological / central nervous system symptoms develop and the age of the dog at the time of diagnosis.

Other people at high risk for serious flu complications, who should strongly consider a flu shot if they haven't gotten one yet, include those with underlying medical conditions such as asthma, diabetes, heart disease and neurological conditions; pregnant women; those younger than 5 years or older than 65 years of age; and anyone with a weakened immune system.