Sentences with phrase «neuronal axon»

The researchers found that puffing activated a mechanosensitive channel protein called TRPV4, which is enriched in the membrane of neuronal axons and allows calcium ions to enter the cell.

Researchers from The Ohio State University have announced they have discovered how blows to the head cause numerous small swellings along the length of neuronal axons.

The HMS study reveals that the aberrant behavior of an enzyme called RIPK1 damages neuronal axons by disrupting the production of myelin, the soft gel - like substance enveloping axons to insulate them from injury.

The delivery is active along neuronal axons, which function like highways in human societies.

Oxidative stress can also lead to loss of neurons or neuronal axons from the colon and consequently a loss of motility.

Not exact matches

Neuronal activity typically requires sensory input — for example, a taste or smell — that gets received by neurons» dendrites and then transmitted as an electrochemical message to other cells via long axons.

The genes we detect are involved in the regulation of cell development, and are specifically important in synapse formation, axon guidance and neuronal differentiation.

Oligodendrocytes, the cells that are known to produce the myelin sheaths which enable saltatory conduction of action potentials along the myelinated axons, are modulators of signal transmission along neuronal connections (axons) and also promote neuronal survival by providing metabolic support.

At one point, the researchers witnessed a microglial cell creeping, amoeba - like, through densely interwoven nerve fibers as it displaced a neuronal cell body and its bundle of axons.

In dendrites and axons these rapid structural and functional changes occur concurrently — their length, size, shape, and number change to suit the needs of neuronal cell body communication.

This means Ind - Cl not only inhibits inflammation but is capable of reducing axon degeneration and restoring neuronal function.»

In those cases, it's imperative to block SARM and Axed signaling to preserve axon integrity, and in turn neuronal function.

The material delivery by lots of carriers in highway - like axons ensures healthy neuronal activity and is a significant finding in the field.

Studies conducted by Hendry at the Australian National University and by K. Stockel and H. Thoenen at the Basel Institute for Immunology have demonstrated that NGF is taken up at the terminal nerve endings of the sympathetic fibers and transported back to the neuronal cell body along the axon.

Rab5 and its effector FHF contribute to neuronal polarity through dynein - dependent retrieval of somatodendritic proteins from the axon.

Activity - dependent relocation of the axon initial segment fine - tunes neuronal excitability.

The laboratory has a particular focus on neuronal polarity — the structural and functional differences between axons and dendrites — and the mechanisms that underlie polarized targeting of membrane proteins.

Figure summarizing the three major steps of axon development in the CNS: axon specification during neuronal polarization, axon growth and guidance, axon branching and presynaptic development (Modified from Lewis, Courchet and Polleux, The Journal of Cell Biology, 2013).

The labelling is for acetylated tubulin in red (identifying all axons), and green for the cell permeable dye calcein, which is only applied on the axonal side of the chambers (top half) and allows the identification of those neuronal cell bodies (bottom half) that have extended axons to the other side of the microfluidic device.

Farhy - Tselnicker I, van Casteren ACM, Lee A, Chang VT, Radu Aricescu A, Allen NJ (2017) Astrocyte - Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation.

Myelin sheaths wrap axons, the long, thin neuronal projections used to communicate with... >> MORE

Myelin sheaths wrap axons, the long, thin neuronal projections used to communicate with other neurons.

Oligodendrocytes also provide metabolic and nutritional support for axons, and thus play critical roles in neuronal survival and integrity.

This is supported by post-mortem studies showing a modest loss of mDA axons in the striatum 1 year after PD diagnosis, with a complete loss of mDA striatal innervation in patients 4 years after diagnosis, while some mDA neuronal soma remained [6].