Sentences with phrase «neuronal cellular communication»

Not exact matches

The affected mitochondria could no longer provide the synapses with enough energy, which ultimately prevented the synapses from functioning — providing the first direct link between cellular injury caused by amyloid protein and the characteristic breakdown of neuronal communication that occurs in Alzheimer's patients.

The research identifies a series of cellular and molecular events that may contribute to differences in neuronal connectivity that underlie the social and communication deficits observed in autism.

Our work has given rise to novel experimental results, which have helped to demonstrate the existence of bidirectional communication between astrocytes and neurons, the active participation of the astrocytes in neuronal physiology and synaptic transmission, and the cellular and molecular mechanisms involved.

''... we hypothesize that repeated stress - related allostatic overload may affect brain function at three basic levels: (a) at the cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and induce epigenetic changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the brain's regulation of behavior (cognitive decline).