Sentences with phrase «neuronal plasma membrane»

Proteomic identification of protein targets for 15 - deoxy - d - prostaglandin j (2) in neuronal plasma membrane.

«Creating a realistically complex neuronal plasma membrane mixture was quite challenging and highlighted a number of gaps in the current understanding of membrane biology,» Ingolfsson said.

Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.

Not exact matches

«Both the neuronal and average human membrane models — arguably the most compositionally complex plasma membrane lipid models to date — showed non-ideal lateral lipid mixing at different length and time scales, demonstrating the inherent complexity of biological membranes.»