In previous studies on rodents, postdoctoral scholar Clemenson and others showed that exploring the environment resulted in the growth of new neurons that became entrenched in the hippocampus» memory circuit and increased
neuronal signaling networks.
Not exact matches
Their work implicated the Ras pathway — a calcium - dependent
signaling network that spurs
neuronal growth — as playing a key role in autism.
We are also interested in other
neuronal functions of the TSC
signaling network, such as the control of neuron size, myelination, survival and stress responses.
They sprouted tiny projections, called dendritic spines, which receive
signals from other neurons in a circuit, and six out of the seven organoids that grew for at least eight months formed active
neuronal networks, spiking with electrical activity.
This whole
neuronal network was also activated through chemosensory anxiety
signals.
To elucidate functional roles of specific
neuronal populations,
signaling mechanisms and ion channel types, in active
neuronal networks, and in the brain of behaving animals.