Both drugs inhibit reuptake, or reabsorption, of
these neurotransmitters by neurons, thus prolonging their action.
Not exact matches
It is considered an inhibitory
neurotransmitter, which means it regulates brain and nerve cell activity
by inhibiting the number of
neurons firing in the brain.
Modafinil also indirectly alters the action of glutamate, the main
neurotransmitter used
by neurons in the brain to send signals down the line.
When a
neuron sends a message it releases the
neurotransmitter serotonin, which is detected
by the next
neuron receiving the message.
The symptoms of Parkinson's — which is characterized
by stiffness and can lead to a loss of motor and speech function — are triggered
by the progressive death of
neurons in a midbrain region called the substantia nigra that produce the
neurotransmitter dopamine (implicated in the pleasure and reward systems as well as in the maintenance of proper movement control).
One set does this
by increasing levels of the
neurotransmitter GABA that quiets
neurons, including some of those the brain's reward system.
These antidepressants, which often have fewer side effects than others, prevent transmitting
neurons from quickly soaking serotonin back up that has not been absorbed
by receptors on other
neurons, thus giving the
neurotransmitter more time in the synapse to exert an effect.
While analyzing molecules excreted
by TRPV1 cells in search of anything that might be itch - specific, Hoon and his colleagues came across a small group of the
neurons that produce natriuretic polypeptide b (Nppb), a hormone that regulates heart function and can also act as a
neurotransmitter.
After isolating the gene, Wu's team determined that when working properly, Wake helps shut down clock
neurons of the brain that control arousal
by making them more responsive to signals from the inhibitory
neurotransmitter called GABA.
AMPA receptors are activated
by the excitatory
neurotransmitter glutamate and are important to both how spines are shaped and how well
neurons receive incoming signals for action.
In
neurons, the protein complexin clamps otherwise spontaneous fusion
by SNARE proteins, allowing
neurotransmitters and other mediators to be secreted when and where they are needed as this clamp is released.
This decision appears to be generated
by a very small number of excitatory
neurons that use acetylcholine as their
neurotransmitter located in three brain regions.
Further tests showed that the activation of specific inhibitory
neurons — parvalbumin, somatostatin, and vasointestinal peptide — was responsible for these changes and was in turn controlled
by the chemical messenger, or
neurotransmitter, acetylcholine.
It is caused
by the loss of brain cells (
neurons) that produce dopamine, an essential
neurotransmitter that allows
neurons to «talk» to each other.
Neurons release
neurotransmitters that are taken up
by specific receptors, but many glial cells receive and emit
neurotransmitters that float through the brain as free agents.
Many antidepressants that target serotonin work
by blocking serotonin transporters that reabsorb the
neurotransmitter into a
neuron, so it can be reused after it has sent a chemical signal.
Such atypical antipsychotic medications as Clozaril (clozapine), Risperdal (risperidone) and Zyprexa (olanzapine), most of which were introduced in the 1990s, appear to ameliorate schizophrenia symptoms
by affecting the function of
neurotransmitters such as dopamine and serotonin, which relay chemical messages between
neurons.
For example,
neurotransmitter molecules might escape from one synapse, and diffuse away to be sensed
by a more distant
neuron.
Dopamine (which is connected to reward processing, motivation and attention) is one of the brain's primary
neurotransmitters, the chemical messengers
by which one
neuron triggers its neighbor to fire a nerve impulse.
WHEN DISCUSSING
neurotransmitters, most people think of the classical
neurotransmitters, such as dopamine and serotonin — the primary chemical messengers used
by neurons to communicate with one another and with other types of cells.
Astrocytes also form their own long - distance communication networks
by «talking» via waves of calcium ions, and, like
neurons, they can receive and release
neurotransmitters.
A supercharged microprocessor Each of the 100 billion
neurons in the human brain is an elaborate processor powered
by neurotransmitters.
Genetic analysis of the activated cells in the two groups of mice showed that the
neurons triggered
by a full belly released glutamate, a chemical that nerve cells use to signal one another, while the
neurons triggered
by hunger released a different
neurotransmitter, known as GABA.
«We were able to develop this very novel method to go to a single
neuron and manipulate how it computes»
by using drugs to block
neurotransmitters at the level of a single nerve cell in a frog brain, and then measuring what happens to that
neuron in response to frog calls, Alluri says.
The mechanism of presynaptic facilitation, therefore, may include activation of one or more serotonergic
neurons, which enhance the release of a
neurotransmitter by increasing the intracellular concentration of cyclic AMP in the terminals of the sensory
neurons.
Fluoxetine and related drugs block the reuptake of serotonin, a
neurotransmitter strongly tied to emotion,
by nerve cells, or
neurons.
«The
neuron is discharging
neurotransmitters, being excited
by these inflammatory signals,» Perron says.
Through studying the brains of these mice, the team uncovered that the faulty gene inhibits
neurons,
by releasing excess of the
neurotransmitter GABA.
The basic process
by which signals pass through the brain involves
neurotransmitters, which are carried inside the synaptic vesicles, being passed across synapses — the junctions between
neurons.
Researchers have discovered that a new
neurotransmitter — a chemical message sent
by neurons — exists in the roundworm C. elegans.
Others had shown that the
neurotransmitter glutamate was released
by some STG motor
neurons.
Marder's PhD work - which earned her a paper in the journal Nature - was to reveal that a second
neurotransmitter, acetylcholine, was released
by other STG
neurons.
The toxins principally affect muscle - controlling motor
neurons activated
by the
neurotransmitter acetylcholine.
Important advances have included the discovery of the first evidence that the odour response is governed
by neurons, of the intracellular signalling pathways between odorant receptors and sensory
neurons, and of specific
neurons, receptors and
neurotransmitters involved in behaviour adaption following experience.
It is theorized that
neurotransmitters modulate the electrical information passed back and forth between
neurons, and thus the corresponding behaviors dictated
by neurons (such as moving your arm or leg).
In the late 1970s, she revealed that the striatum, rather than being an amorphous mass of
neurons, instead consisted of discrete clusters of
neurons, «striosomes» (surrounded
by «matrix»), that were visible upon staining for different
neurotransmitters and their receptors.
The molecular mechanisms
by which midbrain dopamine
neurons acquire the inhibitory
neurotransmitter GABA for synaptic release are revealed.
The first, cholinesterase inhibitors, act
by inhibiting the breakdown of the
neurotransmitter, or
neuron - to -
neuron chemical messenger, acetylcholine.
Choline is a precursor for the
neurotransmitter acetylcholine, which is especially important in memory and mood, and it is also the transmitter most often used
by neurons that communicate between the brain and the nerves controlling skeletal muscles, heart rate, breathing, sweating and salivation.
Dopamine — this functions as a
neurotransmitter which is a chemical released
by neurons or nerve cells to send signals to other nerve cells.
The H reflex is regarded as a measure of α - motor
neuron excitability at the spinal level, but it can also be affected
by inhibitory effects from Golgi tendon organ Ib afferents or
by factors affecting
neurotransmitter release at the Ia / α - motor
neuron synapse (Palmieri et al. 2004).
By blocking adenosine, caffeine increases the firing of
neurons and release of
neurotransmitters like dopamine and norepinephrine.
LSD wakes up the brain
by blocking seratonin the
neurotransmitter of the inhibitory
neurons that ordinarily keeps the brain down to 10 % brain use.
Skeletal muscle contraction is stimulated
by the emission of the
neurotransmitter acetylcholine (ACh)
by the motor
neuron, and terminated
by acetylcholinesterase (AChE) in the neuromuscular junction (NMJ).