Sentences with phrase «neurotrophic factor expression»

Over the course of seven days, researchers showed that doses of both 50 and 100 mg / kg of saponins extracted from Asian ginseng exerted significant antidepressant effects, presumably by reversing neurotrophic factor expression in the hippocampus.

Taylor, S.L., Stanek, L.M., Ressler, K.J., and Huhman, K.L. Differential brain - derived neurotrophic factor expression in limbic brain regions following social defeat or territorial aggression.

Not exact matches

In the hippocampus, a major component responsible for memory, neural activity, synapse formation and expression of brain - derived neurotrophic factor (BDNF) were reduced in these mice (Image 2).

This observation has fueled interest in upregulating SMN2 expression any developing neuroprotectants or neurotrophic factors that could help, Dr. De Vivo said.

Expression of the mRNA encode for Glial cell line - Derived Neurotrophic Factor (GDNF) was detected in cumulus cells as shown previously [22] as well as oocytes in our study.

Pathological changes in the brain were observed, and the expressions of brain - derived neurotrophic factor (BDNF) and extracellular signal - related kinase (ERK1 / 2) were determined to explore the mechanism of BB extract - induced benefits.

The aim of the present study was to determine whether unmodified hNPCctx could rescue visual functions and if engineered expression of a neurotrophic factor could enhance such effects.

Over a decade since this original study, it is now generally accepted that physical activity benefits the brain potentially through the increased expression of the brain - derived neurotrophic factor (BDNF).

The delicate balance between the human microbiome and the development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.

Furthermore, deleterious stress responses are associated with a decrease in the expression of brain - derived neurotrophic factor (BDNF), a response quite the opposite of calorie restriction and intermittent fasting, where increased concentrations of BDNF have been observed in numerous studies (4).

It stimulates the expression of hundreds of protective genes, and creates Brain - Derived Neurotrophic Factor (BDNF), which is necessary to grow new neurons and help them survive.

Robust changes in expression of brain - derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma.