Two of three vaccinated dromedary camels — known carriers of the MERS virus — produced
neutralizing antibodies against the virus.
Not exact matches
This one - two punch protected the test subjects
against influenza A
viruses that had emerged in 1934 and 2007, and other experiments showed that the
antibodies it generated successfully
neutralized a wide variety of flu strains.
Just over a year ago, the same team of South African researchers reported in Nature Medicine (also part of the Nature group of journals) on their discovery relating to two other KwaZulu - Natal women, that a shift in the position of one sugar molecule on the surface of the
virus led to the development of broadly
neutralizing antibodies against HIV.
-- Hyperimmune globulin, prepared by purifying and concentrating plasma of immunized animals or previously infected humans with high titers (concentrations) of
neutralizing antibody against Ebola
virus, which have been shown to be protective in monkeys but are not currently available and would not be expected before mid-2015.
Neutralizing antibodies primarily recognized the envelope protein domain III (EDIII) or quaternary epitopes on the intact
virus, and an EDIII - targeted
antibody protected mice
against lethal infection.
The
antibodies against H7subtype
viruses exhibit «remarkable
neutralizing potency,» and thus may represent a new way to protect people who have been exposed to or infected by avian influenza, they reported today in The Journal of Clinical Investigation.
The study, published in Scientific Reports, demonstrated that animals injected with synthetic DNA engineered to encode a specific
neutralizing antibody against the dengue
virus were capable of producing the exact
antibodies necessary to protect
against disease, without the need for standard antigen - based vaccination.
Neutralizing antibodies are necessary and sufficient for protection
against infection with vesicular stomatitis
virus (VSV).
These so - called broadly
neutralizing antibodies (bNAbs) do little to help the people who produce them, but their existence indicates that mutations have created an increasingly diverse population of the
virus, which in turn has pushed the immune system to evolve a response that is both more potent and works
against more variants.
A major goal of HIV - 1 vaccine development is to identify immunogens capable of inducing protective titers of broadly
neutralizing antibodies (bNAbs)
against circulating, neutralization - resistant (tier 2)
viruses.
At day 49, the mice that received the mRNA vaccine produced high levels of
neutralizing antibodies against Zika
virus in their blood compared to placebo.
The findings also suggest that a substantial degree of protection can be achieved
against stringent
virus challenges, even in the absence of high levels of tier 2
neutralizing antibodies.
She explained that when you give a vaccine antigen, which is the protein of the
virus or bacteria you're immunizing
against, you actually
neutralize any existing
antibody directed specifically
against that same antigen.
If you give that puppy the distemper
virus vaccine, it will
neutralize some of the existing immunity
against the
virus, leaving the animal vulnerable until the new
antibodies from the vaccine take over.