Sentences with word «neutropenia»

Researchers reported that patients with neutropenia who received any prophylactic therapy were far less likely than those who did not to develop fever, documented or likely infections, or bloodstream infections.

We can conclude that primary or secondary prophylaxis of febrile neutropenia with G - CSF is justified, but patients at higher risk for thrombocytopenia should be treated with caution.»

This is known as neutropenia.

The therapy did appear to be reasonably safe: nearly all of the relatively small number of adverse events that occurred during the course of the trial were mild; the six moderate - severity adverse events and the one severe event (a case of neutropenia) were judged to be unrelated to the treatment.

One of Dr. Innocentis exemplary achievements is the elucidation of the genetic basis of severe neutropenia in cancer patients treated with irinotecan, a poster child for pharmacogenetic.

The expected neutropenia is less severe and patients recover more quickly, reducing their risk for infectious complications.

The most commonly reported side effects were a decrease in certain populations of immune cells, conditions called neutropenia and leukopenia, an expected effect that indicates the drug is working.

Neulasta (pegfilgrastim) is a man - made prescription drug form of a protein that is used to stimulate the growth of white blood cells in your body, and is primarily prescribed to prevent neutropenia in those who are receiving chemotherapy.

Kikuchi, M., Inagaki, T., and Hanaki, H. Effect of copper and zinc supplementation on peripheral leukocytes in neutropenia due to copper deficiency.

Canine cyclic neutropenia (CN), also known as gray collie syndrome (GCS), is an autosomal recessive disease.

She co-founded the association in 1989, as the only charity in the world focused on severe chronic neutropenia, and is currently serving as the association's president.

There was one death during the study, possibly resulting from febrile neutropenia caused by the treatment.

However, your dog to fight off infection is impaired by neutropenia.

When Malakai turned one, he was diagnosed with chronic benign neutropenia, a blood condition which - despite the «benign» name in its label - leaves him with a weakened immune system, lowered white blood cell count, and as a byproduct, requires him to have daily breathing treatments.

Commenting on the findings, Dr Stefan Zimmermann, Senior Consultant, Medical Oncology Department, HFR — Hôpital Cantonal, Fribourg, Switzerland, said: «Oncologists do need G - CSF to mitigate neutropenia and increase chemotherapy delivery and compliance, but want the beneficial effect of timely concurrent therapy to outweigh the toxic risks.»

The patient experienced transplantation - related side effects during the time prior to receiving CTL019, including neutropenia and thrombocytopenia, nausea, fever, and an infection.

For this study, patients received a starting dose of hydroxyurea that was escalated in a stepwise manner until patients reached a predetermined maximum dose (either 35 milligrams per kilogram daily or 2,000 milligrams daily) or experienced mild neutropenia.

About 2 percent of patients in this study developed transitory neutropenia, or a low level of disease - fighting white blood cells called neutrophils.

University of Washington School of Medicine Therapeutic inhibition of aberrant protease activity in inherited neutropenias

Serious neutropenia occurred in 5.8 % of pemetrexed patients and in no placebo patients.

Researchers reported that preventive therapy with levofloxacin or other antibiotics reduced the odds of infection, including fevers and bloodstream infections, by 70 percent or more in ALL patients with neutropenia during induction therapy.

Upon examination of the blood, it may reveal neutropenia (an abnormal decrease in the number of neutophils / white blood cells), which confirms the presence of the canine parvovirus infection.

Recombinant human granulocyte colony stimulating factor for treatment of puppies with neutropenia secondary to canine parvovirus infection.

Signs: sudden death, collapse, vomiting, dehydration, massive neutropenia as neutrophils flood into the gut, other white blood cell numbers may be normal.

This Teachable Moment uses the case of a woman in her 30s undergoing chemotherapy for stage 2A breast cancer who was hospitalized for febrile neutropenia to illustrate the need to avoid overtreatment for low - risk patients with this common oncological complication.

I have an autoimmune disease (called neutropenia).

Dopamine prevented neutropenia (low neutrophil count) induced by 5 - FU, an anti-cancer drug commonly used to treat gastrointestinal cancers.

His lab discovered the genetic bases of gray platelet syndrome, Hartnup disease, arterial calcification due to deficiency of CD73, 3 - methylglutaconic aciduria type III, 3 types of HPS, and neutropenia due to VPS45 deficiency.

CLPB mutations cause 3 - methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder.

These early weeks of chemotherapy often lead to a drop in white blood cells known as neutropenia that leaves patients at risk for life - threatening infections that can delay cancer treatment.

Cyclic neutropenia: a condition characterized by periodic lowering of neutrophils, a type of white blood cell.

The patient was being treated for severe neutropenia and a viral infection when he joined the study.

Among 38 patients given G1's trilaciclib ahead of the same chemo treatments, just two experienced grade three neutropenia.

Methotrexate (for arthritis): Can suppress the baby's immune system; unknown effect on growth or association with carcinogenesis; neutropenia.

Cyclophosphamide: May suppress the baby's immune system; unknown effect on growth; association with carcinogenesis; neutropenia.

Thirteen patients developed anemia, a low white cell count (neutropenia), and / or neurological symptoms, all of which are typically associated with zinc induced copper deficiency, say the researchers.

The most common adverse side effects were neutropenia (a shortage of certain white blood cells), muscle spasms, cough, diarrhea, fatigue, and hypertension.

The most common adverse side effects were lymphopenia (a condition of abnormally low levels of white blood cells called lymphocytes), neutropenia, blood platelet deficiency, and infection.

The treatment was well - tolerated, and the most common adverse events were hematological in nature, such as grade 4 neutropenia (75 percent) and grade 3 febrile neutropenia (21 percent).

Because invasive aspergillosis is so deadly, the guidelines recommend some patients at highest risk be treated with antifungals to prevent infection, including those with neutropenia and graft versus host disease (GVHD).

In addition, people undergoing chemotherapy who develop febrile neutropenia, associated with low levels of white blood cells, might benefit from the role of Del - 1 in supporting the production of immune - related blood cells such as neutrophils.

Among the side effects of the combined treatment, 16 patients experienced neutropenia, a low count of the infection - fighting white blood cells called neutrophils; five patients with neutropenia had fevers; three patients became anemic; and two patients developed thrombocytopenia, a lowered count of blood - clotting platelets.

Furthermore, the agent prevented the drop in the number of neutrophils (i.e., neutropenia) found in the blood that is typically caused by 5 - fluorouracil, a chemotherapy agent commonly used in the treatment of gastrointestinal and other tumors, such as colon, stomach, pancreas and breast cancers.

Common adverse events (AEs) associated with inotuzumab ozogamicin include abdominal pain, anemia, fatigue, febrile neutropenia, headache, hemorrhage, hyperbilirubinemia, infection, leukopenia, liver damage, nausea, neutropenia, pyrexia, and thrombocytopenia.