Not exact matches
AMD is described in stages — early, intermediate, and late — with vision loss occurring in late - stage AMD, either from atrophy or
abnormal new blood vessels.
Roughly 20 percent of patients with age - related macular degeneration suffer from
abnormal blood vessel growth and vascular leakage, says Campochiaro, and so may be helped by this
new therapy, if it proves to work in clinical trials.
Working with mice, a multicenter team of researchers has found a
new way to reduce the
abnormal blood vessel growth and leakage in the eye that accompany some eye diseases.
Ultimately, Wars2 provides researchers and pharmaceutical companies a fresh
new target for developing treatments for diseases characterized by
abnormal blood vessel growth that may be more effective and specific or complementary to what is currently available.
These
abnormal cells — in the case of pulmonary hypertension, those that line the
blood vessels leading to the lungs — release signals that stimulate the growth of small
new blood vessels to feed the renegade cells, allowing further proliferation, and thickening of the
vessel walls.
Choroidal neovascularization (CNV), the underlying process causing wet AMD and
abnormal blood vessel growth, is the body's misguided way of attempting to create a
new network of
blood vessels to supply more nutrients and oxygen to the eye's retina.
That was the research niche that we set out to explore to see if we could find a
new way of targeting the
abnormal blood vessel growth that occurs in wet AMD.
These
abnormal cells release signals that stimulate the growth of small
new blood vessels.