Sentences with phrase «new alleles at»

To continually produce more extreme variation despite these purifying forces requires the dog genome to create new alleles at an extraordinary rate.

Not exact matches

Piroska Szabó of the Van Andel Research Institute in Grand Rapids, Michigan, was once excited to think she'd discovered a new gene that expressed only the maternal allele — until she realized that the RNA sequences she was looking at were from a gene that had been misannotated as a nuclear gene, explaining the maternal - only inheritance.

Any combination of somatic insertions or deletions (indels) in the p.R259fs allele that restored the reading frame before the stop - gain at residue 274, and did not produce a new stop - gain, would produce an almost full - length BRCA2 protein.

Research at VetGen and independently at the University of Saskatchewan has identified two new alleles in the E locus, Eg and Eh.