When Parham compared the HLA genes of people from different regions of the world with the Neanderthal and Denisovan HLAs, he found evidence that non-African humans picked up
new alleles from the hominins they interbred with.
So, if a gene lies within a gene - dense, low - recombination region, then this means that a much larger number of progeny from crosses must be examined to find those that derive from rare recombinational events that separate the desired
new allele from undesirable forms of neighboring genes.
Not exact matches
Each Pm3
allele in the four
new lines displayed the same activity as in the parental line, which results in increased overall activity, since it came
from two different gene variations.
Initially the people who drank milk
from cows had something unusual about them, but by chance the
new allele improved the welfare of human beings on their way north.
SNP calling, genotype calling, and sample
allele frequency estimation
from new - generation sequencing data Nielsen, R. T. Korneliussen, A. Albrechtsen, Y. Li et al. 2012.
The
new passenger pigeons (birds carrying a fully edited set of
alleles from each parent) will form the first true generation of de-extinct passenger pigeons.
Piroska Szabó of the Van Andel Research Institute in Grand Rapids, Michigan, was once excited to think she'd discovered a
new gene that expressed only the maternal
allele — until she realized that the RNA sequences she was looking at were
from a gene that had been misannotated as a nuclear gene, explaining the maternal - only inheritance.
A failure to identify
new unc - 124
alleles led us to sequence the unc - 7 coding region cloned
from unc - 124 (hs10) mutants (strain HH34), and a TGC to TAC change (C238Y) in the predicted second TM domain of UNC - 7 was identified.
The RECIPIENT (i) shall register the
alleles carried by mice with a
new mutation engineered
from the MATERIAL with Mouse Genome Informatics (MGI), and (ii) is requested to submit breeding pairs to a public repository for cryopreservation and distribution to third parties for non-commercial purposes on terms substantially the same as these Conditions of Use.
Although the
newest edition of the authoritative textbook, Vitamin D, claims that in humans calcidiol binds with equal affinity to the DBP whether it is derived
from vitamin D2 or vitamin D3, 37 the citation for this statement is the author's own PhD thesis, in which he reported results obtained
from testing the DBP of a mere two people.48 Since the gene for the DBP is one of the most polymorphic known (meaning it exists in many forms), existing in three common
alleles and 124 known rarer
alleles (
alleles are specific forms of the same gene), each
allele itself having many polymorphisms, 37 a sample size of two is rather unconvincing.