Not exact matches
There was an
ancient paradigm about the «fitness cost of antibiotic resistance,» but the emergence of the
new technologies of high - throughput sequencing has changed the field, allowing researchers to study bacterial pathogenesis at the
genome scale,» said Dr. David Skurnik, senior author of a
new Bioessays article.
New DNA recovery and sequencing technology is at last allowing scientists to assemble entire
genomes of
ancient scourges — and elusive modern ones
Accessing
Ancient Genomes —
New techniques and very old bones pushed back the limits of
genome sequencing for our early ancestors.
New techniques and very old bones overcome the limits of
genome sequencing for prehistoric horses,
ancient cave bears, and even our own early ancestors.
This
new work, which hints that other horses may be represented in these
ancient genomes, shows «that [horse] domestication could have been a process with many phases, experiments, failures, and successes,» says Ernest Bailey, a geneticist at the University of Kentucky's Gluck Equine Research Center in Lexington.
A
new study uses
ancient DNA to suggest that a massive migration of herders from the east shaped the
genomes of most living Europeans — and that these immigrants may have been the source of Proto - Indo - European (PIE), the mysterious ancestral tongue from which the more than 400 Indo - European languages sprang.
Browning's team used a
new technique to trawl for segments of
ancient DNA in the
genomes of 5600 living humans from Europe, Asia, America and Oceania.
The study broke
new ground in other areas as well, yielding the first
ancient whole
genomes of East Asian ancestry and the highest coverage
ancient human
genome from Asia (7x coverage) sequenced to date.
The sequencing of
ancient genomes is still so
new, and it's changing the way we reconstruct human origins
Palaeontologists don't know what the Denisovans looked like, but studies of DNA recovered from their teeth and bones indicate that this
ancient population contributed to the
genomes of modern humans, especially Australian Aborigines, Papua
New Guineans and Polynesians — suggesting that Denisovans might have roamed Asia.
... modern humans exist in environments that are critically different from those in which we evolved, and that our
new environments interact with our
ancient genomes to lead to disorder... In this perspective, these functions may or may not be adaptive in modern environments, but historically accomplishing these functions has promoted fitness and that is why the symptoms of depression have evolved.
However, the ultimate factor underlying diseases of civilization is the collision of our
ancient genome with the
new conditions of life in affluent nations, including the nutritional qualities of recently introduced foods.