Small victories build
new androgen receptors in the areas of the brain responsible for reward and motivation.
Not exact matches
A
new University of Colorado Cancer Center study being presented today at the Endocrine Society Annual Meeting shows that even triple negative breast cancers expressing very low levels of
androgen receptor may benefit from this therapy.
The
new research found that on top of their known effects on cancer, Hsp90 inhibition also blocked production of abnormal forms of the
androgen receptor, stripping cancer cells of their defences against hormone treatments.
Using a
new TaqMan PCR - based technique, the researchers screened a number of cancer cell lines from various tissues, and discovered that tRNA halves were specifically expressed in large quantities in sex hormone - dependent cancers, i.e., estrogen
receptor (ER)- positive breast cancer and
androgen receptor (AR)- positive prostate cancer that are driven by the hormones estrogen and testosterone.
Aberrant activation of
androgen receptor in a
new neuropeptide - autocrine model of
androgen - insensitive prostate cancer.