Sentences with phrase «new bacterial resistance»

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«When you get resistance for a common infection, it's a big problem, which we're sort of ignoring a bit like global warming,» said Dr. Colin Broom, the CEO of Nabriva Therapeutics, a biotech firm developing a new antibiotic to treat community - acquired bacterial pneumonia.

Bacterial blight nevertheless remains an important concern and many countries will not endorse the release of new rice varieties unless they carry resistance to the disease.

There was an ancient paradigm about the «fitness cost of antibiotic resistance,» but the emergence of the new technologies of high - throughput sequencing has changed the field, allowing researchers to study bacterial pathogenesis at the genome scale,» said Dr. David Skurnik, senior author of a new Bioessays article.

A new pattern of antibiotic resistance that is spreading around the globe may soon leave us defenseless against a frighteningly wide range of dangerous bacterial infections

But the mounting burden of diseases means that newer and more effective medications must be developed; for example, bacterial resistance is growing globally, pushing our need for novel antibiotics.

If so, and if researchers can identify the exact sugars responsible, those molecules might be converted into desperately needed new antibiotic drugs that could sidestep some of the problems, such as bacterial resistance, with existing antibiotics.

With this new understanding of how bacterial populations evolve survival strategies against antibiotics, scientists could develop new approaches for slowing the evolution of antibiotic resistance.

«While human microbes are natural to humans, enclosed environments over-enriched in human bacteria might facilitate transmission of bacteria or bacterial traits, such as antibiotic resistance, for example MRSA,» said Maria - Gloria Dominquez - Bello, associate professor at New York University School of Medicine and lead author of the study.

A recent study from a U.K. commission on antimicrobial resistance estimated that by 2050, antibiotic - resistant bacterial infections will kill 10 million people per year, if no new drugs are developed.

Research focused on the utilisation of viruses that infect and kill bacteria, known as bacteriophages or phages, in preventing infectious diseases has gained new traction after bacterial resistance to antibiotics has become a global problem.

It shows that new drugs which are introduced to circumvent known resistance mechanisms, as methicillin was in 1959, can be rendered ineffective by unrecognized, pre-existing adaptations in the bacterial population.

A new study led by University of Kentucky researchers suggests a new approach to develop highly - potent drugs which could overcome current shortcomings of low drug efficacy and multi-drug resistance in the treatment of cancer as well as viral and bacterial infections.

To help on this front, in a new paper published in the journal Structure, researchers from McGill University present in atomic detail how specific bacterial enzymes, known as kinases, confer resistance to macrolide antibiotics, a widely used class of antibiotics and an alternative medication for patients with penicillin allergies.

And a new antibiotic can not compete with older drugs that are off - patent and therefore cheap, until bacterial resistance makes the old drugs useless.

Last month WHO issued a report that warned of an increase of antimicrobial - resistance and the renewed threat of bacterial infections world - wide and called for a concerted effort to develop new and better antimicrobial drugs.

The researchers found four new chemicals that seek out and disrupt bacterial proteins called «efflux pumps,» known to be a major cause of antibiotic resistance.

This sort of bacterial adaptation has contributed to the rising problem of antibiotic resistance, which has prompted scientists to look for new ways to treat infection.

The new DETECTR system, created at UC Berkeley based on CRISPR - Cas12a, can analyze cells, blood, saliva, urine and stool to detect genetic mutations, cancer and antibiotic resistance as well as diagnose bacterial and viral infections.

The availability of molecular markers for these genes, which help breeders improve the accuracy and speed of developing new varieties, has made improving resistance to bacterial blight more efficient.

Using new techniques they developed, the investigators identified almost 800 genes in these bacterial communities that confer resistance to antibiotics.

Current research applications focus on new approaches to a) drug and probe development for neurodegenerative disorders and diseases including Schizophrenia, Alzheimer's, and Parkinson's, b) understanding the structural determinants of antidepressant binding to neurotransmitter transporters, c) cardiac arrhythmia as caused by the complex interplay of potassium channel regulation and drug interactions, d) multidrug resistance in cancer and bacterial cells related to multidrug transporter proteins, and e) structural basis of viral infections and antibody activity.