Dr. Gan and her team discovered
new cellular mechanisms that could lead to novel approaches to remove toxic proteins from aging neurons.
As researchers at the Max Planck Institute of Biochemistry report in the current issue of Nature, they have now decoded
a new cellular mechanism for the development of aggregates.
Not exact matches
The more primitive virus, however, carries no repair
mechanisms; a
new virion (complete virus) acquires lipids for its envelope by literally ripping them off of the
cellular membrane as it buds off from the infected cell.
Now, scientists at Princeton have used «designer chromatin'templates — highly customized replicas of
cellular DNA and histone proteins, the scaffolding proteins around which DNA is wrapped — to reveal
new details about Suv39h1's
mechanism.
However, the researchers found that a well - known
cellular mechanism — one that controls how proteins acquire
new functions — also plays a major role.
«First aid kit in some living organisms helps fix DNA after lengthy sun exposure:
New study unveils the binding
mechanisms of enzymes capable of repairing DNA damaged by UV light before any risk of
cellular malfunction sets in.»
A
new study, however, provides insights on the
cellular mechanisms that might be targeted to help certain stem cells - called human mesenchymal stem cells (hMSCs)- maintain properties needed to make them clinically useful.
But Skalak says Allen intends to fund such established scientists» work in «wholly
new» areas: Doudna, for example, will explore a
new mechanism to edit
cellular function by targeting RNA.
It thus seems quite likely that this
new signaling path also links the performance of the
cellular power plants and cell division in human cells,» says Meisinger, who now plans to analyze these
mechanisms in tumor tissues.
The results of the research open
new possibilities for understanding the
cellular mechanisms responsible for genome instability and for being able to explore
new therapeutic approaches.
The
new enzyme converts A to a base called inosine, or I. Either a
cellular repair
mechanism or the process of the DNA copying itself then changes the I to a G. «The big deal here is engineering the TadA enzyme to do something fairly unnatural,» says George Church of Harvard, who studies CRISPR.
«Our research reveals a
new regulatory
mechanism that coordinates two distinct intracellular processes that are critical to
cellular homeostasis and disease development,» said Chengyu Liang, M.D., Ph.D., a member of the USC Norris Comprehensive Cancer Center and principal investigator of the study.
The findings add a
new level of complexity to our understanding of the
cellular mechanisms of taste perception, which may ultimately lend insight into individual differences in food preferences and dietary choices.
Therefore, our findings could provide
new insights into an «old»
cellular defense
mechanism against invading viruses.»
Examination of such
mechanisms by which the brain naturally protects itself may lead to more selective
cellular and molecular targets, as well as
new therapeutic strategies against brain disease.
She is currently studying the
cellular and genetic
mechanisms of liver cancer with the hope of identifying
new biomarkers and drug targets for this often fatal disease.
New research from King's College London has revealed a previously undiscovered
mechanism of
cellular communication, between neurons and immune cells, in neuropathic pain.
Now, a
new study from University of Georgia
cellular biologists shows the
mechanism behind tubulin transport and its assembly into cilia, including the first video imagery of the process.
The lab focuses on clarifying the
mechanisms of brain plasticity, gene expression, and responses of
cellular elements to different psychotropic drugs, and have identified several novel brain sites and pathways that constitute attractive targets for
new drug development.
In this
new paper, the researchers reveal more about that
mechanism, showing that without the protective ability of BRCA1, breaks in the DNA strands go unfixed, prompting the molecule ATM kinase to activate a
cellular «suicide» pathway involving a protein called p53.
A
new study implicates a key
cellular mechanism as defective in SMA for the first time, providing a
new lead for developing future interventions.
This project has the potential to uncover clinically relevant
mechanisms of
cellular senescence in fibrosing ILDs and identify
new therapeutic targets
By uncovering the precise
cellular mechanisms of nicotine's effect, this study suggests
new and more precise targets for drugs designed to block this powerful craving.
Our team is using a combination of cutting - edge proteomics, molecular and
cellular biology strategies to uncover
new alt - EJ players and decipher their
mechanisms of action in cancer.
The exception is this
new research, published March 22 in Cell, which identifies the key
cellular mechanisms behind vascular aging and the key role it plays on muscle health.
A just - published
new study pulls back the curtain to show how quercetin operates at a
cellular level to foil cancer - promoting
mechanisms in the body.
Because the pathophysiology of cancer is linked to alteration of
cellular gene expression, the bioinformatics toolbox promises to offer countless molecular insights into
mechanisms, diagnostics, and
new medical interventions for cancer.
Fortier Laboratory Dr. Lisa Fortier's laboratory investigates the underlying
cellular and molecular
mechanisms involved in the development of arthritis with the goal of identifying finding
new ways to treat and prevention arthritis.
London, England About Blog Exploring the molecular
mechanisms that underpin key biological processes, the Biochemical Journal is a leading bioscience journal publishing high - impact scientific research papers and reviews on the latest advances and
new mechanistic concepts in the fields of biochemistry,
cellular biosciences and molecular biology.