Scientists have discovered
a new cellular pathway that can promote and support the growth of cancer cells.
Not exact matches
«This
new study extends those original mechanistic findings to the amyloid
pathway and preservation of
cellular and synaptic connections.
This study reveals how lipids control SH2 domain - mediated
cellular protein interaction networks and suggests a
new strategy for the therapeutic modulation of pY - signaling
pathways.
The team's findings suggest that the egg's special
cellular vesicles represent a
new type of system that is a unique combination of three separate biological processes whose
pathways may have diverged from their classic functions.
Hokkaido University researchers have uncovered a
cellular protein that stabilizes a tumor promoting signaling
pathway, suggesting a
new target to treat prostate cancer.
«We found that a specific
cellular pathway, AMPK - PGC1a, likely plays a key role to reduce mitochondrial function and content, which means that
new therapeutic approaches that restore and increase mitochondrial function and content could ameliorate or perhaps even arrest chronic kidney disease.»
«The discovery of these
new, natural grape - derived polyphenol compounds targeting
cellular and molecular
pathways associated with inflammation may provide an effective way to treat a subset of people with depression and anxiety, a condition that affects so many people.»
«
New cellular garbage control
pathway with relevance for human neurodegenerative diseases.»
Scientists in the laboratory of Stefan Jentsch at the MPIB now successfully used baker's yeast for screening for
new cellular waste disposal
pathways.
These studies will provide
new leads to understand the
cellular pathways that control K2P function in other organisms.
His lab went on to molecularly decode a number of
new components of this
cellular starvation
pathway, which connects nutrition and exercise to suppression of both cancer and diabetes.
The lab focuses on clarifying the mechanisms of brain plasticity, gene expression, and responses of
cellular elements to different psychotropic drugs, and have identified several novel brain sites and
pathways that constitute attractive targets for
new drug development.
In this
new paper, the researchers reveal more about that mechanism, showing that without the protective ability of BRCA1, breaks in the DNA strands go unfixed, prompting the molecule ATM kinase to activate a
cellular «suicide»
pathway involving a protein called p53.
Through systematic annotation of the resulting movies, we developed a phenotypic profiling system, which shows high correlation with
cellular processes and biochemical
pathways, thus enabling us to predict
new functions for previously uncharacterized genes.
Altieri and his team are currently focused on three programs to understand the biology of survivin with respect to cell cycle progression, in particular, mitosis, cell survival and the
cellular stress response and how exploiting these
pathways may provide
new cancer therapeutics.
Characterizing the molecular
pathways regulating genomic stability at damaged replication forks in HR - deficient cancers will increase our understanding of the
cellular response to replicative stress, and in the same time, potentially allow the identification of
new predictors (biomarkers) of chemo - sensitivity / resistance in these tumors (Figure 2B).
March 13, 2017 Parallel
cellular pathways activate the process that controls organ growth A
new study from the University of Chicago suggests that while proteins that control organ growth accumulate around the edges of cells, they actually function at a different
cellular site.