Testing
a new class of compounds, Senolytics, on their ability to extend healthy lifespan by clearing out dysfunctional cells in the body.
«
New class of compounds shrinks pancreatic cancer tumors, prevents regrowth.»
(GlaxoSmithKline has decided to stop marketing ezogabine but other existing drugs that also operate by tweaking potassium channels in brain cells — or a wholly
new class of compounds — could serve in its place.)
Minoryx is also working on
a new class of compounds: non-competitive pharmacological chaperones, identified through its innovative proprietary platform — SEE - Tx.
Not exact matches
Metal organic
compounds produce a
new class of glass, according to The Pennsylvania State University.
«Our computer aided drug screening process has now identified two
new classes of anti-cancer agents, specifically targeting two distinct and novel mechanisms underpinning cancer,» said Dr Andrea Brancale from Cardiff University's School
of Pharmacy, who led on the
compound's design.
«In this case, the combined expertise
of the industry, which has the resources to develop
new compounds, and the academia, which has the research and lab capabilities to understand how the
compounds work, have enabled the development
of this
new class of antibiotics,» Mankin said.
The family
of defense
compounds, including Sigillin A, is unique in that it is a
new class of natural products that features a chemical scaffold that could find application in insect control.
It is a member
of an entirely
new class of alkaloids; it is an organochlorine
compound, which is rarely found in animals; and it is a powerful painkiller.
Seeking to exploit this weakness and develop a
new class of antifungals, an international group
of researchers screened a synthetic drug library for
compounds that target the synthesis
of fungal but not mammalian GlcCer.
In work published online today in the journal PNAS, researchers at the Instituto de Medicina Molecular (IMM), in Lisbon, Portugal, have discovered a
new class of highly potent antimalarial
compounds.
«
New class of highly potent antimalarial
compounds discovered.»
The main objective
of the Institute conducted fundamental research - to obtain
new data on the structure and transformations
of organic
compounds, their mechanism
of chemical reactions, the synthesis
of organic
compounds,
new classes,
new opening reactions, the development
of new catalysts and to investigate the relationship
of their structure to the catalytic activity.
Currently,
new classes of SMA - specific
compounds have been identified.
A
new, but rapidly growing body
of experimental research now indicates that this is simply not true, and there is a
class of heart - tissue regenerating
compounds known as neocardiogenic substances.
If g is too large then no matter how small an allocation you make to the
new asset
class, it drags down the expected
compound return
of the
new portfolio, even taking into account the bump from lower volatility.
However, if the
new asset
class has a lower expected return than the original portfolio, then this will tend to reduce the expected
compound return
of the
new portfolio.
Although this
class of compounds has shown efficacy in a variety
of cancers, interest in developing
new topoisomerase I inhibitors, indenoisoquinolines, are currently being evaluated in human patients as agents with improved drug stability and measurable blood levels.
The
new JCAP photocathode construct consists
of the semiconductor gallium phosphide and a molecular cobalt - containing hydrogen production catalyst from the cobaloxime
class of compounds.