Dr. Yang's team has developed
the new class of protein - based contrast agents and tested one called ProCA32 that enabled a much earlier detection of liver cancer tumors in mice.
In the late 1990s — with the advent of
a new class of protein - based drugs, monoclonal antibodies — demand sometimes outstripped supply.
There are several
new classes of proteins found in grain.
Not exact matches
(Reuters)- Alnylam Pharmaceuticals Inc's RNAi - based drug that targets a rare genetic disease met the main goal
of a key study, in a breakthrough for the
new class of medicines that works by blocking disease - causing
proteins.
«A
new class of antibiotics to combat drug resistance: Newly discovered antibiotic binds to ribosome, disrupts
protein synthesis.»
Bohn noted isoquinolinone 2.1 is one example
of a
new class of «biased» kappa agonists that avoid many central nervous system side effects by preferentially activating a G
protein - mediated signaling cascade without involving another system based on β - arrestin
protein interactions.
Gevorg Grigoryan, an assistant professor
of computer science at Dartmouth College, and researchers from other institutions have built the first artificial transporter
protein that carries individual atoms across membranes, opening the possibility
of engineering a
new class of smart molecules with applications in fields as wide ranging as nanotechnology and medicine.
The researchers set out to «build» an artificial transporter
protein from scratch, to learn how transporters work, and to open the possibility
of engineering a
new class of smart molecules.
Ledipasvir belongs to a promising
new class of DAA drugs that work by blocking the NS5A
protein, which the hepatitis C virus also needs to replicate.
A
protein found in some animals could lead to a
new class of biosensors for detecting environmental contamination or airborne disease
Trebananib (formally known as AMG 386; Amgen) is a first - in -
class peptide - Fc fusion
protein (or peptibody) that targets angiogenesis (the growth
of new blood vessels into cancerous tumors) by inhibiting the binding
of both angiopoietin 1 and 2 to the Tie2 receptor.
Researchers at UT Southwestern Medical Center have identified a second role for a
class of RNA - binding
proteins, revealing
new insights about neurological diseases and conditions associated with this
protein such as autism, epilepsy, and certain types
of cancer.
Their research is published in the Journal
of the American Chemical Society in an article titled «Discovery
of a
New Class of Non-beta-lactam Inhibitors
of Penicillin - Binding
Proteins with Gram - Positive Antibacterial Activity.»
Juan Bonifacino's lab at the National Institute
of Child Health and Human Development, for one, had discovered the role a certain
protein plays as asymptomatic infection progresses to AIDS but testing
of a
new class of potential HIV medications had to be stopped due to the shutdown.
Peptide nucleic acid, a synthetic hybrid
of protein and DNA, could form the basis
of a
new class of drugs — and
of artificial life unlike anything found in nature
Using the potent drug WEHI - 842, we were able to stabilise the
protein sufficiently to detail its molecular structure, which will be critical in developing this
new class of antimalarial drugs.»
The first three - dimensional image capturing a critical malaria «conductor»
protein could lead to the development
of a
new class of antimalarial drugs.
In 2012, a group from the RIKEN Center for Life Science Technologies, in collaboration with SISSA, an Italian University, discovered a
new class of mouse lncRNAs, which are called «antisense» because their can pair with typical
protein - coding mRNAs and enhance their translation.
A
new strategy for engineering
protein fusions — to make specific cell - targeted drugs without side effects — could enable a safer, more potent
class of protein drugs.
This
new class of antibiotics works against TB by disrupting the function
of a part
of the cell known as the ribosome, which is responsible for
protein synthesis.
Then, a
new class of enzymes — SNO synthases — convert NO into SNOs, that attach to
proteins and modulate their function.
In the course
of seeking
new treatments for brucellosis, scientists discovered that Brucella contains a
class of signaling
proteins called LOVs.
Their results, the researchers conclude, «show that computationally designed
proteins have potent anti-viral efficacy in vivo and suggests promise for development
of a
new class of HA stem - targeted antivirals for both therapeutic and prophylactic protection against seasonal and emerging strains
of influenza.»
Ceapins are a
new class of unfolded
protein response inhibitors, selectively targeting the ATF6a branch.
Protein disulfide isomerase inhibitors constitute a
new class of antithrombotic agents.
«
Of particular interest, we identified two new virulence proteins that revealed a new class of secreted virulence proteins and that we are currently investigating,» said PNNL scientist Dr. Charles Ansong, one of the investigator
Of particular interest, we identified two
new virulence
proteins that revealed a
new class of secreted virulence proteins and that we are currently investigating,» said PNNL scientist Dr. Charles Ansong, one of the investigator
of secreted virulence
proteins and that we are currently investigating,» said PNNL scientist Dr. Charles Ansong, one
of the investigator
of the investigators.
Leelamine could be the first
of a
new unique
class of drugs that will simultaneously target several
protein pathways.
Dr. Vilcek's contributions to the understanding
of proteins that control the body's defenses were instrumental in the development
of the anti-inflammatory drug Remicade ®, the first member
of a
new class of therapeutics called TNF blockers that are now widely used for the treatment
of Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, and other chronic inflammatory disorders.
eFFECTOR is pioneering a
new class of small molecule drugs that act by selectively regulating translation, also known as
protein synthesis.
In the
New York Times bestseller The Plant Paradox, Dr. Steven Gundry introduced readers to the hidden toxins lurking in seemingly healthy foods like tomatoes, zucchini, quinoa, and brown rice: a
class of plant - based
proteins called lectins.
Biologically Appropriate ™ ORIJEN represents a
new class of food, designed to nourish dogs and cats according to their evolutionary adaptation to a diet rich and diverse in fresh meat and
protein.