Sentences with phrase «new computational analysis»

Not exact matches

Data access and analysis tools are being made available for the 3K RGP dataset through the International Rice Informatics Consortium (IRIC), which promotes collaboration in bioinformatics analysis of rice data and provides computational tools to facilitate rice improvement via discovery of new gene - trait associations and accelerated breeding.

In addition, using methods for the analysis of regulatory networks developed by the Califano lab in the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce new hair growth.

Careful attention to phenotyping diseases, facilitated by our knowledge of the human genome and computational analysis, has allowed observant physicians and physician - scientists to identify and categorize diseases in a manner that has informed basic science, given it new contexts, and in many instances provided important new directions for investigation.

The tested values matched those determined by computational analysis using the new formulas, Ren said.

«We synthesized a new compound, demonstrated its effectiveness with biological data, and learned more about its interactions with proteins through X-ray crystallography and computational analysis,» says UConn associate professor of chemistry José Gascón, a specialist in quantum and molecular mechanics.

Planetary scientist Will Grundy of Lowell Observatory in Flagstaff, Ariz., and colleagues used images of Charon taken by the New Horizons spacecraft and computational analysis to demonstrate that methane from Pluto is a reasonable culprit for Charon's rust - colored pole.

«We are currently working on parameter sensitivity analysis and Bayesian calibration of this new model and also on a high resolution regional simulation over the U.S. Corn Belt, all of which would not be possible without the precious computational resources provided by Blue Waters.»

A new study published in PLOS Computational Biology provides the first in - depth analysis of the mouth clicks used in human echolocation.

My group's research focuses on the development of new computational methods for analysis of DNA from the latest sequencing technologies.

We're rolling out new workshops and webinars on topics like Probabilistic Seismic Hazard Analysis (PSHA) and computational seismology, providing enhanced support for student and early - career members, and creating a strong network of advocates for geosciences — more important now than ever before — through our public policy programs in Washington, D.C. Membership is an introduction to a growing and global community preparing for our first joint meeting with the Latin American and Caribbean Seismological Commission in April 2018.

We also want to make it easy for computational researchers to develop and share new analysis approaches.

We intend to provide a few simple portals as a starting point, but new portals can be developed by anyone in the scientific or computational community, for a wide diversity of use cases, including: clustering, differential interference, spatial reconstruction, visualization, and graph - based analysis.

«We synthesized a new compound, demonstrated its effectiveness with biological data, and learned more about its interactions with proteins through X-ray crystallography and computational analysis.»

Computational Algorithms and Tools (Bruce Aronow, Section Editor): This section focuses on the generation of databases, analysis tools, or large scale analyses carried out from new or established datasets that generate hypotheses into the structure and function of physiological systems at the sub cellular or organismal level.

Later in the 1970s, theorists used new analyses and some of the first computational plasma physics studies to show that the picture was much less bleak than originally thought.

She joined 23andMe in 2007 and manages the 23andMe research team, which is responsible for consumer health and ancestry research and development, academic and industry collaborations, computational analyses for therapeutics, and new research methods and tools development.

Abecasis leads the University's Biostatistics department, which is training a new generation of scientists and making contributions to the statistical and computational machinery for the analysis of diverse types of biomedical data — including not only genomic data but also electronic health records, registry data and health surveys, a variety of imaging data types, and environmental exposures, among others.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

His analysis of all publicly available cancer mutations and integration with all solved computational models of human proteins has created a powerful roadmap for evaluating new mutations observed in patient tumors.

New computational strategies are supported by our single cell data analysis experts with computational methods deconvolute tissue composition, determine cell type heterogeneity, identify novel cell type defining markers or track transcriptional dynamics.

Data access and analysis tools are being made available for the 3K RGP dataset through the International Rice Informatics Consortium (IRIC), which promotes collaboration in bioinformatics analysis of rice data and provides computational tools to facilitate rice improvement via discovery of new gene - trait associations and accelerated breeding.

It matches to the new arrangements and provides slides on all the content within the following: Development methodologies Analysis Design Implementation (data types and structures) Implementation (computational constructs) Implementation (algorithm specification) Testing Evaluation These slides have worked wonderfully well with my class and have made new parts of National 5 much more accessible to my classes.

Examples may include systems science approaches (e.g., computational modeling and simulation, network analysis, and engineering control methods) to conceptualize prevention at the micro - or macro-levels of analyses; alternative intervention designs for when randomization is not possible; new methods for optimization of interventions; adaptive interventions and SMART designs; and innovative analytic approaches including time varying effect models, and models for incorporating intensive longitudinal data and / or real time data capture in prevention science research.

GM proprietary computational fluid dynamics (CFD) analysis techniques were used to develop an all - new combustion system with a higher compression ratio.

The new combustion system developed with GM's proprietary computational fluid dynamics (CFD) analysis software features a higher compression ratio which helps improve fuel efficiency and has improved knock resistance.

«Fifty Years Later epitomizes the impact of Bowdoin's newly launched Digital and Computational Studies Initiative, which works collaboratively to apply digital tools to the humanities» materials in order to facilitate their study and analysis from new and rich perspectives,» continued Gieseking.