Sentences with phrase «new drug targets»
If additional work supports the finding, the study may provide researchers with potential new drug targets for the disease.
sciencemag.org
Other programs will use cellular models of heart disease created from stem cells to identify potential new drug targets.
The researchers say there is an urgent need for new drug targets in major depressive disorder.
A better understanding of the process affected in the brain will lead to identification of new drug targets, and potentially, life - changing preventive therapies or treatments.
With this method, it is possible to analyze huge volumes of data to discover new drug targets, which can lead to the development of effective cancer medications.
Consequently, many research groups are in hot pursuit of finding new drug targets and designing novel ones against the disease.
Such individuals could shed light on the function of many genes and point to new drug targets if the knocked - out gene somehow protects against disease.
In two advanced lung cancer trials, which we covered, new drugs targeting familiar faulty molecules showed promise.
Both research teams are trying to discover potential new drug targets that not only reduce skin discomfort and itch, but also are safer and associated with fewer side effects than currently available therapies.
Resistance to drug treatments is spreading among the parasite's many strains, and researchers are working hard to find new drug targets.
He hopes that further studies may identify novel approaches to immune - based cancer therapy or reveal new drug targets for inflammatory diseases.
Gauri's work focuses on identifying new drug targets against tuberculosis and understanding the mode of action against such targets.
«RNA splicing machinery offers new drug target.»
«Epigenetic alteration a promising new drug target for heroin use disorder.»
Structural biologists have obtained important scientific results likely to advance efforts to develop new drugs targeting NMDA receptors in the brain...
We help our clients better understand the function of genes, basic mechanisms of biology, pathophysiology of diseases, to identify and validate new drug targets and to perform risk assessment in drug development.
O - GlcNAc regulatory system adds complexity in cell regulation, could eventually provide new drug targets
Emulate and Takeda Partner to Use Intestine - Chip for New Drug Target Identification and Validation in Drug Development for GI Diseases
While there are currently no treatments for preeclampsia other than premature delivery of the baby, the researchers are also investigating new drug targets.
Further, trials for new drugs targeting at - risk patients can be ramped up significantly if a simple, non-invasive blood test can replace costly imaging like PET scan.
Toward the goal of precisely augmenting telomerase activity selectively within adult stem cells, this discovery reveals the crucial step in telomerase catalytic cycle as an important new drug target.
This, in turn, has been implicated in cancer and offers an interesting new drug target to be studied further.»
«The long term goal is to get new drug targets that are specific for bipolar disorder,» says team member Ian Blair of the Garvan Institute of Medical Research in Sydney.
University of California, Berkeley researchers have now found a promising new drug target within that pathway that is appealing, in part, because it appears to control production of only a few percent of the body's many proteins, those critical to regulating the growth and proliferation of cells.
Just as physicians hope that decoding the genomes of harmful viruses and bacteria could offer tempting new drug targets, plant scientists look to genomes for new defenses against bugs that attack plants.
Preliminary genetic evidence included in the study suggests that the enzyme, called SNRK, performs similar functions in humans, making it an intriguing new drug target in the battle against obesity and its complications.
«Following the exciting discovery that dengue virus NS1 protein can directly cause vascular leak, the hallmark of severe dengue disease, we have now succeeded in disentangling the mechanisms responsible, suggesting new drug targets for inhibiting severe dengue,» says Dr. Eva Harris, the senior investigator.
This work presents a possible new drug target for cancer and heart disease, and was published in the journal, Nature Communications, on 8 July 2016.
Hear about the Science Exchange's Reproducibility Initiative, which aims to reward high - quality, reproducible research and provide a mechanism for industry to identify robust new drug targets for the development of effective new therapies.
our stroke research, we will soon be able to find a gene within the type 2 diabetes locus we have identified and use this gene to identify powerful new drug targets.»
I am interested in understanding how genetic polymorphisms in genes encoding PTPs can mediate disease pathogenesis, and in defining new drug targets for immune - mediated diseases among the PTPome.
Unexplored Toxic Pathways in Alzheimer's: Potential New Drug Targets Shahrnaz Kemal, PhD Northwestern University (Evanston, IL)
This may also have implications for antiobesity treatment in humans, because new drugs target these key regulators of energy balance, restoring impaired POMC neuron function.
«New drugs targeting HDAC3 could provide an exciting avenue to allow older people to improve memory formation,» Wood said.
«Revealing new drug targets against H. contortus could provide much - needed new treatment opportunities against parasitic worms in both animals and humans.
Ahead of us now is the major task of exploring the potential of new drug targets, so that hopefully we can prevent the number of people with untreatable infections from escalating further,» says Professor Anders Miki Bojesen, who coordinates the UC - Care research activities at the Department of Veterinary Clinical and Animal Sciences.
That should get easier thanks to a mass - screening technique reported in the 1 February issue of Science that may provide a cost - effective and powerful way to pick out new drug targets against cancer.
Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA - approved treatment that affects 200,000 people per year in the United States.
Looking at cancer genetics inthis broader way is helping Emerson to discover new drug targets that may be used to prevent or treat cancers.
«Virtual tissue technology reveals new drug target in polycystic kidney disease: Advanced computer simulations show that failures of cell adhesion and inhibition cause two types of kidney cyst formation.»
Government and industry will kick in $ 230 million over 5 years to find new drug targets for Alzheimer's, diabetes, arthritis, and lupus
The Novo Nordisk R&D center was first established in 2002 to optimize recombinant protein production, but is now moving on to do «real project work and be more innovative,» including developing new drug targets.
It aims to better understand the function of genes, basic mechanisms of biology, physiopathology of diseases, to identify and validate new drug targets and to perform risk assessment in drug development.
We are pleased to announce our partnership with Takeda, to use our Intestine - Chip for new drug target identification and validation in drug development for GI diseases
«Master regulator of key cancer gene found, offers new drug target.»
«This hampers integration of lipidomics into systems biology, and addressing it will improve our fundamental understanding of lipid biology, help identify new drug targets for therapy and discover lipid biomarkers from disease cohorts.»
Corporate partnerships also included the expansion of a collaboration with Takeda Pharmaceutical Company to search for new drug targets for a variety of diseases.
«When kids» autistic brains can't calm down: Mutation is linked for first time to seizures in autism and is new drug target.»