Sentences with phrase «new effector»

Over evolutionary time, the bacterial and plant populations have engaged in an arms race, where the bacteria evolve new effector proteins to help them sneak in, while the plant acquires new defense proteins to uncover and respond to the attack.

The team additionally identified a new effector pathway for alloreactive T cells.

Not exact matches

The new concept is called effector - triggered defense or ETD.

Our research enhances the traditional understanding of the plant defense system and describes a new concept describing how plants protect themselves against the pathogens that grow in the space outside plant cells (the apoplast)-- a new concept called effector - triggered defense or ETD.»

«It is likely that rapid evolvement of new bacterial effectors contributed to the resurgence of this disease.»

«Previously it was thought that HIV was hiding primarily in central memory T - cells, but our new HIV genetic sequencing test has revealed that the majority of replication - competent virus is actually hiding in effector memory T - cells.

As the end products and biological effectors of gene expression, proteins are crucial for improving our understanding of human biology, developing new and better drugs, and advancing precision medicine.

«What these new findings on exhausted T cells tells us is that the unique epigenetic profile of exhausted T cells causes these cells to express a different overall set of genes compared to memory or effector T cells,» Wherry said.

Further insight into the basic details of CRISPR - Cas structure, functions, and biology — and characterization of new Cas effector proteins in particular — is crucial for optimizing and further expanding the diverse applications of CRISPR - Cas systems.

These studies can lead to the development of new methods or the improvement of existing ones but are driven mainly by the primary goal of finding useful effectors of the target proteins.

They will also prepare a list of the genetic codes of the fungus — the so - called effectors — that are responsible for the ability of the fungus to adapt to new wheat varieties.

The variety of new tools available for genetic manipulation now include lentiviral - based gene delivery, and gene editing using CRISPR / Cas9, zinc finger nucleases (ZFNs) or transcription activator - like effector nucleases (TALENs).

Stephen Alexander, UK - Cannabinoid receptors, transporters, endocannabinoid turnover, hydrogen sulphide turnover Arthur Christopoulos, Australia (GPCRs Liaison)- G protein - coupled receptors; analytical pharmacology; allosteric modulation; biased agonism; drug discovery; neuropharmacology John Cidlowski, USA (NHRs Liaison)- Glucocorticoid receptor signaling; apoptosis and the immune system Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison) Doriano Fabbro, Switzerland - Kinases and their biology, kinase inhibitors, drug discovery, pharmacology of drugs (kinase inhibitors) in the indication oncology, biology of oncology Kozo Kaibuchi, Japan Yoshikatsu Kanai, Japan - Transporters, amino acid signals, epithelial function, cancer biology Francesca Levi - Schaffer, Israel - eosinophils and mast cells as effector cells in allergic inflammation: characterization of new receptors / ligands, hypoxia / angiogenesis and eosinophils, asthma, atopic dermatitis, allergic rhinitis, immunopharmacological modulation of allergic diseases by bispecific recombinant antibodies, bacteria interactions with eosinophils and mast cells, the allergic effector unit, mast cell derived tumors: new antibody based treatment, the allergic inflammation and the resolvome, non IgE - mediated mast cell activation in diseases Eliot H. Ohlstein, USA (Editor)- Drug discovery and development, urogenital biology, cardiovascular / metabolic medicine John A. Peters, UK (LGICs Liaison) Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Joerg Striessnig, Austria (VGICs Liaison)- Physiology, pharmacology and pathophysiological role of voltage-gated calcium channels