Sentences with phrase «new gene delivery»

Not exact matches

Anderson and others are already exploring new gene - delivery methods, including nanoparticles, to better deliver gene - editing therapies to target tissues.

«New gene - delivery therapy restores partial hearing, balance in deaf mice.»

Initial tests on mice showed the hybrid virus was very efficient: the gene it carried was active in 24 per cent of airway cells after two months, a far better proportion than achieved by other delivery methods (New Scientist, 10 March 2001, p 19).

Dr Wenxin Wang is trying to uncover therapies for diseases such as diabetic ulcers and Epidermolysis Bullosa, which causes chronic skin conditions: «We are currently investigating the use of these new materials for biomedical applications such as drug / gene delivery, cross linkable hydrogel materials and skin adhesives.

Now, to enable widespread gene delivery throughout the central and peripheral nervous systems, Caltech researchers have developed two new variants of a vector based on an adeno - associated virus (AAV): one that can efficiently ferry genetic cargo past the blood - brain barrier; and another that is efficiently picked up by peripheral neurons residing outside the brain and spinal cord, such as those that sense pain and regulate heart rate, respiration, and digestion.

Unofficially, says Nicholas, the EPA has always maintained that any new gene added to a plant to produce a pesticide is itself a pesticide, while the plant serves as a delivery system.

Yehoash Raphael, an auditory neuroscientist at the University of Michigan, Ann Arbor, says the findings provide a new delivery model for researchers trying to use developmental genes to restore lost hearing.

In particular, the advanced drug delivery systems he has developed provide new methods for nanoparticulate drug delivery, non-viral gene therapy, siRNA delivery, and vaccines.

«The failure rate to deliver drugs to CNS is unfortunately very high, so any new methods of drug, protein and gene delivery should be welcome,» says Inder Verma, Ph.D., a professor in the Laboratory of Genetics and senior author of the study published in the Proceedings of the National Academy of Sciences.

This new study tested delivery of SUMO - 1 gene therapy alone, SERCA2 gene therapy alone, and a combination of SUMO - 1 and SERCA2.

New delivery technique used to create a glowing adult mouse potentially opens the door for in vivo gene therapy

Then after that the next cycle of development will will focus on diversification of gene therapies, given standard practices for delivery and putting a new therapy into the market.

The program will be packed with papers on biochromatography, downstream processing, QbD, monoclonal antibodies, plasmids, enzymes, vaccines, viral vectors for gene delivery, VLPs, and other biopharmaceuticals, chiral molecules, SFC, fine chemicals, peptides, proteins, oligonucleotides, APIs, natural products, batch, multi-column and continuous SMB processes, column technology and equipment, monoliths, new and improved stationary phases, membrane chromatography, regulatory aspects, and more!

The variety of new tools available for genetic manipulation now include lentiviral - based gene delivery, and gene editing using CRISPR / Cas9, zinc finger nucleases (ZFNs) or transcription activator - like effector nucleases (TALENs).

Basically, the cells to be reprogrammed are removed from their normal culture system and exposed to the genes (in a gene delivery system), then put back into a new culture system.

New delivery system developed by MIT team deletes disease - causing genes and reduces cholesterol.

«The failure rate to deliver drugs to CNS is unfortunately very high, so any new methods of drug, protein and gene delivery should be welcome,» says Verma.

Mooney uses the results from these studies to design and synthesize new biomaterials that regulate the gene expression of interacting cells for a variety of tissue engineering and drug delivery projects.

«Research topics vary from improving corneal wound healing with new proteins to gene delivery targeting retinal disease,» she said.