Sentences with phrase «new gene expression»

Long - lasting changes in brain connectivity require new gene expression, and Dr. Martin has discovered a role for specific signaling molecules that travel from stimulated synapses to the nucleus to change the transcription of DNA to RNA.

Dartmouth Institute for Quantitative Biomedical Sciences (iQBS) researchers developed a new gene expression analysis approach for identifying cancer genes.

This new gene expression data therefore provides additional evidence that the altered behavior of bacteria in space results from decreased gravity driving reduced extracellular transport of molecules.

Not exact matches

Often, the genes of the new are present in the body of the old — they are the ideas, the social movements, the fair food networks that start life on the innovative edge, the social fringe, and move towards the middle where they give expression to the new systems that grows out of the old.

The recent Lancet Breastfeeding Series refers to new discoveries being made about breastmilk — such as its role in gene expression — so it can be expected that Nestle will use the strategy of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily in epigentics research).

A new study in Biological Psychiatry found that heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

A new meta - analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder — all previously unlinked to Parkinson's.

We wanted to understand what types of differences are always there, what is causing them, and what they mean,» says Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory and co-senior author, with Kelly Frazer of the University of California, San Diego, on the new paper, which was published in Cell Stem Cell in April 2017.

Now, new research suggests changes at the epigenetic level — specifically alterations in proteins that affect gene expression, rather than genetic mutations — could be driving childhood ependymomas.

«The reversible nature of the m6A methylmark adds a new layer to the regulation of gene expression now termed «epitranscriptomics» and warrants further research to establish links with human disease such as cancer,» adds Dr Irmgard Haussmann of Coventry University.

Among the historical figures bound by the thematic thread of dna in journalist Sam Kean's new book are Charles Hapsburg, whose weak chin was the result of royal inbreeding, and a group of Arctic explorers who were poisoned by the Vitamin A in polar bear liver, which threw off their gene expression.

In a new study published in Physiological Genomics, a team of U.S. researchers tracked in detail how this extreme makeover is controlled by changes in gene expression.

It, therefore, offers a new way to study the role of the environment on the expression of our genes.

«The world of RNA opens new dimensions to gene control and gene expression,» Rassoulzadegan says.

The Epstein - Barr virus, which infects some 90 % of Americans, may cause changes in gene expression that dramatically increase a person's chance of getting lupus and six other autoimmune disorders, a new study by Harley, now a rheumatologist at the Cincinnati Children's Hospital Medical Center in Ohio, and colleagues shows.

These new piRNAs bind to a nuclear PIWI protein to repress the expression of the jumping gene in the nucleus.

By examining gene expression patterns, the new study found that parrot brains are structured differently than the brains of songbirds and hummingbirds, which also exhibit vocal learning.

A decade of post-genomic biology has also focused new attention on the regions outside protein - coding genes, many of which are likely to have key functions, through regulating the expression of protein - coding genes and by making a slew of non-coding RNA molecules.

Scientists from the Biogerontology Research Foundation (BGRF), a UK - based charity founded to support aging research and address the challenges of a rapidly aging population, propose a new concept for signalome - wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

A new study from the Institute of Food Research has uncovered a mechanism by which Salmonella bacteria organise the expression of genes required for infection.

This work provides a proof of principle for a new approach in the study and treatment of cancer: the aberrant expression in a tissue or organ of genes specific to other tissues could become a new tool for establishing a prognosis and personalizing therapeutic care.

The new gene - expression test for bacterial infection faces two hurdles before it can be made available to doctors in a few years.

«Single - nucleus RNA sequencing, droplet by droplet: DroNc - Seq, technology that merges single - nucleus RNA sequencing with microfluidics, brings new scale to gene expression studies in complex tissues.»

The new work, published today in Cell Reports, finds that the protein ADR - 1 binds to messenger ribonucleic acid, or mRNA, and then enhances RNA editing, a process that allows a gene to be present as multiple mRNAs that can then each affect gene expression differently.

Using an innovative crystallization technique for studying three - dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the «magic spot» — a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

A new effort by DOD, NCI, and the Department of Veterans Affairs will profile gene and protein expression in thousands of individuals» tumors.

New markers suggested include total mass of hemoglobin, altered expression of genes related to red blood cell metabolism, ironomics, storage lesions, and the presence of plasticizers from blood bags in athlete urine samples.

The significance of the new model, according to Grange, is that «it enables us to now have a biological understanding of the patterns, the co-expression profiles, seen in the Allen Gene Expression Atlas of the Mouse Brain.»

The Epstein - Barr virus (EBV), which infects some 90 % of Americans, may cause changes in gene expression that dramatically increase a person's chance of getting lupus and six other autoimmune disorders, a new study by Harley and colleagues shows.

On the flip side, turning up expression of these genes or their pathways could help researchers grow new intestinal tissue to replace tissue destroyed by diseases such as inflammatory bowel disease or radiation treatment for cancer.

A molecule in cells that shuts down the expression of genes might be a promising target for new drugs designed to treat the most frequent and lethal form of brain cancer, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).

The axiom, «growing like a weed,» takes on new meaning in light of changes in gene expression that occur when weeds interact with the crops they infest, according to plant scientist Sharon Clay.

In cells grown on flat culture dishes, the expression of thousands of genes didn't match up with their normal patterns, explaining why the cells from those dishes had been unable to generate new hair follicles.

The work, published online this week in the journal Nature, suggests modulation of «enhancer - directed RNAs» or «eRNAs» could provide a new way to alter gene expression in living cells, perhaps affecting the development or pathology of many diseases.

The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.

Our work shows an exciting new way that eRNAs produce these different patterns of gene expression.

In the new study, the team genetically inactivated HIV - 1 in transgenic mice, reducing the RNA expression of viral genes by roughly 60 to 95 percent, confirming their earlier findings.

With no nucleus to further modify and craft gene expression and protein translation, life thrived but literally could not get hold of itself, could not assume new shapes or diversify.

«Because many broadly expressed genes that play key roles in essential cellular functions are under the control of cell - specific enhancers, the ability to affect enhancer function by knocking down eRNAs could potentially provide a new strategy for altering gene expression in vivo in a cell - specific manner,» said Glass, noting that in his research, anti-sense oligonucleotides were developed in conjunction with Isis Pharmaceuticals, which suppressed enhancer activity and reduced expression in nearby genes.

Both papers offer new evidence that eRNAs significantly contribute to enhancer activity, and therefore to expression of nearby genes.

«New major gene expression regulator in fungi: Researchers report prevalent DNA base modification in the earliest fungal lineages.»

A new Tel Aviv University study pinpoints the inverse correlation between a known oncogene — a gene that promotes the development of cancer — and the expression of an oncosuppressor microRNA as the reason for extended pancreatic cancer survival.

«Enhancer RNAs alter gene expression: New class of molecules may be key emerging «enhancer therapy».»

The researchers found that the gene expression levels in immune cells changed in response to the macaque's new social rank within 3 months of establishing the new groups, and the cells got better at fighting infection.

This gene encodes a protein that regulates gene expression, producing a new mutant that gives the seed new properties.

As the end products and biological effectors of gene expression, proteins are crucial for improving our understanding of human biology, developing new and better drugs, and advancing precision medicine.

Scientists at NYU Langone Medical Center and New York University have demonstrated that a specialized DNA - binding protein called CTCF is essential for the precise expression of genes that control the body plan of a developing embryo.

A team of researchers from three departments at New Jersey Medical School, led by Michael Mathews and Hartmut Hanauske - Abel, previously showed that Ciclopirox, commonly used by dermatologists and gynecologists to treat fungal infections, inhibits the expression of HIV genes in culture.