Sentences with phrase «new gene sequences»

In - depth analysis of the human body's microflora has been possible only in the past few years — a by - product of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human genome.

2D nanoparticles known as nanosilicates can be used to grow bone and cartilage tissue from human mesenchymal stem cells, according to new gene sequencing experiments by researchers at Texas A&M University in the US.

Scientists who genetically engineer crops are looking to introduce a desirable trait into that crop, and they do so by inserting a new gene sequence from another species into the target crop's genome.

Not exact matches

That's not to say gene editing is new (it isn't), but Crispr simplifies the process by using molecular scissors that can be precisely targeted to snip out aberrant regions of genetic code, which can then be replaced with the correct sequences.

Synthetic biology is the practice of engineering gene sequences to create new biological systems and devices.

With respect to antibiotic resistance, this novelty can be induced and we can trace the novelty to particular mutations arising absent gene transfer; i.e. the genes which give rise the resistance were not present prior to the mutation, they are new sequences and not simply the activation of dormant genes.

A local philanthropist underwrote purchase of a new Illumina MiSeq device that facilitates targeted gene sequencing.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

«Decoding the genome's cryptic language: New tool to map RNA - DNA interactions could help researchers translate gene sequences into functions.»

In the new study, the researchers sequenced the entire genome of mice that had undergone CRISPR gene editing in the team's previous study and looked for all mutations, including those that only altered a single nucleotide.

Gene discovery was greatly facilitated by a new exome sequencing technology, which analyzes all protein - coding regions of the genome at once.

«Gene sequencing study reveals unusual mutations in endometriosis: Findings advance search for new ways to classify aggressive forms of the disease.»

Based on the transcript sequences, the researchers identified 1,437 new promoters — short DNA sequences where transcription begins — in or between genes, on top of the 1,730 promoters they knew of.

The new analysis, based on data assembled primarily by graduate student Yan - Jie Feng at Sun Yat - Sen University in Guangzhou, China, focused on the sequences of 95 genes located on chromosomes in the nucleus and how they changed over time.

Although the researchers suspected that having more copies of the gene sequence might confer a greater degree of resistance, they had no way of testing their suspicions before the new assay was developed.

The growth of publicly accessible data troves on genome sequences, gene activity, and protein structures and interactions has opened new territory for biologists.

«By inserting the new sequence into the DNA, perhaps they are altering the gene in some other way,» he says.

She and her colleagues sequenced genomic DNA in the tumor samples but did not find any new driver gene mutations in the metastatic samples compared to the primary tumor samples, said McDonald, who completed clinical training under Iacobuzio - Donahue at Johns Hopkins.

More than 80 percent of the viral gene sequences he found were new to science.

A new study suggests that epigenetic effects — chemical modifications of the human genome that alter gene activity without changing the DNA sequence — may sometimes influence sexual orientation.

But by investigating the DNA sequence around the resistance genes, the team figured out how the resistance genes transfer occurred through a new mechanism named «carry back,» where the pathogen basically has a primitive form of «sex» with the Actinobacterium and takes up its resistance genes after it dies.

After his group utilized a new gene - sequencing tool, they posted some unpublished genome data online.

New genome - sequencing research suggests white European people with two copies of variant forms of MC1R, a gene linked to pale skin and red hair, have faces that appear up to two years older than those who are the same age but don't have both copies.

In a new study, researchers are taking joint biopsy tissue from patients at the start of a new therapy and then six weeks later to see if they can find a predictor gene sequence that will clearly identify which patients respond to a particular therapy.

New, sophisticated gene sequencing techniques are leading to an increasing understanding of the causes of genetic disease, and can help parents with affected children make informed reproductive choices, the annual conference of the European Society of Human Genetics will hear.

A new study published in The Journal of Molecular Diagnostics has established that hybrid - capture sequencing is the method of choice for sequencing «actionable» gene mutations across the most common forms of lymphoid cancer.

«Single - nucleus RNA sequencing, droplet by droplet: DroNc - Seq, technology that merges single - nucleus RNA sequencing with microfluidics, brings new scale to gene expression studies in complex tissues.»

«Harnessing the power of genomic sequencing augments diagnosis and treatment of lymphoid cancer: New assay may allow screening for «actionable» gene mutations in routinely acquired archival biopsies, reports The Journal of Molecular Diagnostics.»

They enable molecular biologists and geneticists to selectively chop DNA into pieces, which can then be assembled into new versions of the gene, inserted into the genomes of other organisms, or sequenced as part of an effort to map an organism's genetic material.

Large - scale methods of probing samples, such as DNA sequencing, microarrays, and automated gene - function studies, are filling new databases to the brim.

Suspecting that the other four carried a new Ehrlichia species, the researchers sequenced the bacterial gene in their blood and compared it to a database containing the sequences of known infectious bacteria.

For one such project, the team developed a new software tool called GppFst that allows researchers to differentiate genetic drift — a neutral process whereby genes and gene sequences naturally change due to random mating within a population — from genetic variations that are indicative of evolutionary changes caused by natural selection.

Over the longer term, the identification of the coffee tree genome sequence opens up new possibilities for varietal improvement, knowledge of the specific functions of the genes (in particular those specific to coffee trees), the possibility of transferring results to other species, and refining diagnostic tools for the function of the plant.

His laboratory at the NIH is sequencing 1000 genes each month, but he hopes to produce sequences of 2000 new genes a week.

«However, our new approach uses cutting - edge DNA sequencing technology to precisely measure the effects of thousands of sequences on gene activity at the same time.»

A comprehensive DNA sequencing of pancreatic cancer cases revealed not only a plethora of damaged genes, but potential diagnostic biomarkers that could help identify those with longer or shorter survival, and provide opportunity for new therapeutic interventions.

Matches between new genes from other species, including mammals, and these E. coli sequences have often helped researchers pin a name and function on their discoveries.

By characterising the DNA sequence of these individuals, the project gained insight into the contribution of rare variants to a broad range of disease scenarios, and discovered new genetic variants and genes underpinning disease risk.

The genome - editing technique known as CRISPR allows scientists to clip a specific DNA sequence and replace it with a new one, offering the potential to cure diseases caused by defective genes.

Just as the Human Genome Initiative in the 1990s sequenced human DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applications.

The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.

To begin to grapple with those questions, the researchers involved in the new study first selected as «seeds» the nine genes that have been most strongly tied to ASDs in recent sequencing research from their labs and others.

They also demonstrated significant advantages of editing gene regulatory sequences in their native location to uncover new functionalities that could lead to a better understanding of how control switches work to turn genes on and off in the body.

In the new nomenclature, genetic sequences are labeled «genseq,» followed by a reliability ranking (e.g., 1 if the sequence is from a primary type), followed by the name of the genes from which the sequences were derived (e.g., genseq - 1 16S, COI).

Although aneuploidy does not bring in new genetic sequences, it does make possible another kind of genetic diversity — in which the extra genes produce extra proteins, resulting in an organism that differs from its parents.

A New World monkey joins a growing list of primate species with sequenced genomes, improving genomicists» ability to tell what genes make primates — and humans — unique.

Sequencing the genome and assessing gene activity in various tissues in the tsetse fly led to new insights into its biology and the control of parasitic diseases transmitted by this insect.

COLD SPRING HARBOR, NEW YORK — Even though a draft sequence of the human genome is nearing completion, biologists still have widely varied estimates of how many genes it contains.

In some cases, the missing pieces can be picked up by comparing the new sequences with known sequences of genes from other species.