Yesterday a team of University of Pennsylvania researchers — led by Dr Pablo Tebas, Professor Carl June, and Dr Bruce Levine — announced the successful conclusion of a clinical trial to evaluate the safety of
a new gene therapy technique for treating HIV.
Not exact matches
The
technique has also raised hope for more powerful
gene therapies that can delete or repair flawed
genes, not just add
new genes.
Using a
new technique to deliver
gene -
therapy - like intervention directly where it's needed, researchers at Thomas Jefferson University successfully increased or decreased the muscle tone of the anal sphincter in appropriate animal models.
«If this approach works in humans, it will really change the conversation that providers have with patients,» Scadden said, especially for those «who have these underlying genetic disorders and for who the
new gene - editing and
gene therapy techniques are being developed.»
The benefit of this approach over other
gene therapy techniques is that the
new method can permanently correct the «defect» in a
gene rather than just transiently adding a «functional» one, said Dr. Eric Olson, Director of the Hamon Center for Regenerative Science and Medicine at UT Southwestern and Chairman of Molecular Biology.
The researchers conclude this
technique could eventually lead to
new ways to prepare vast numbers of cells for the coordinated manufacture of
gene therapies.
A
new technique inspired by the immune systems of microorganisms could be a boon for
gene therapy.
With
new techniques involving stem cells,
gene therapy, and tiny electronics, researchers are getting ready to perform that medical miracle.
In this way we hope to lay a clinical groundwork for two
new techniques: liver cell transplantation and liver
gene therapy.»
It is expected that the
new technique will be applied to
gene therapy in the future in addition to providing a powerful tool for breeding useful organisms and conducting disease and drug - discovery research.
B could work as a potential vector for
gene therapy, a
technique that treats diseases by introducing
new genes into cells or by replacing or inactivating
genes already there.
The researchers used the
new technique to mutate the
genes CXCR4 and CCR5, which encode receptor molecules that different strains of the HIV virus use to sneak in and infect immune cells and which have been targeted in previous cell
therapy trials.
New delivery
technique used to create a glowing adult mouse potentially opens the door for in vivo
gene therapy
The idea there is that by identifying
genes that cause, or contribute to glaucoma, and understanding what the protein products of those
genes do, we can use
new techniques to target those proteins to develop
therapies that actually approach the actual disease mechanisms that cause the disease.