A genetic screening approach to studying bone disease has found nine
new genes associated with bone health and suggests a new way to discover genes that may be implicated in human skeletal diseases.
A genetic screening approach to studying bone disease has found nine
new genes associated with bone health and suggests a...
Singapore scientists have identified three
new genes associated with Primary Angle Closure Glaucoma (PACG), a leading cause of blindness in...
a Nature Genetics paper by leading paediatric neurologist and researcher Professor Ingrid Scheffer who revealed two
new genes associated with severe childhood epilepsies
Den Hollander seeks
new genes associated with diseases.
This past September, a pair of research teams announced that they had identified three
new genes associated with Alzheimer's disease.
Published in Nature Communications, the study analysed a population of over 6,000 people with varied ancestry across Latin America to identify
new genes associated with hair color, greying, density and shape, i.e. straight or curly.
The largest - ever study to sequence the whole genomes of breast cancers has uncovered five
new genes associated with the disease and 13 new mutational signatures that influence tumour development.
«
New genes associated with extreme longevity identified.»
This massive dataset is a powerful resource for understanding natural genetic variation in rice as well as for large - scale discovery of
new genes associated with economically important traits.
Phung Thi Phuong Nhung, IRD - CIRAD Ph.D. scholar, started a research project in 2011 on identifying
new genes associated with root developmental traits in a core collection of Vietnamese rice varieties.
Not exact matches
Collaboration based on
new findings from the Regeneron Genetics Center ® showing variant in HSD17B13
gene is
associated with reduced risk of chronic liver diseases
By adding these
new genes, genetic engineers hope the plant will express the traits
associated with the
genes, such as resistance to certain diseases or herbicides.
It greatly increases the accuracy of incorporating only the
gene of interest, and its
associated trait, into a
new rice variety.
Once specific
genes associated with beneficial traits are identified, they can be more efficiently transferred into
new rice varieties using other breeding methods.
A
new study in Biological Psychiatry found that heroin use is
associated with excessive histone acetylation, an epigenetic process that regulates
gene expression.
In the
new research, which was conducted in collaboration with Duke - NUS Medical School in Singapore, scientists used computational techniques to scan thousands of
genes and mutations
associated with epilepsy.
A
new mouse model of a genetically - linked type of autism reveals more about the role of
genes in the disorder and the underlying brain changes
associated with autism's social and learning problems.
In the
new study, Duke University researchers overcame several of these obstacles by using a non-pathogenic carrier called adeno -
associated virus, or AAV, to deliver the
gene - editing system.
A
new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss - of - function mutations to Filaggrin - 2 (FLG2), a
gene that creates a protein responsible for retaining moisture and protecting the skin from environmental irritants, were
associated with atopic dermatitis in African American children.
A second study published in Biological Psychiatry, also led by Dr. Perlis, applied the
new method in a proof - of - concept study to identify
genes associated with psychiatric symptoms.
Perhaps most significantly, in a study led by Frances Champagne — then a graduate student in Meaney's lab, now an
associate professor with her own lab at Columbia University in
New York — they found that inattentive mothering in rodents causes methylation of the
genes for estrogen receptors in the brain.
These differentially expressed microRNAs point the way toward finding more
genes associated with glaucoma, more clues about how these glaucoma types each go about damaging our optic nerve and potential
new points of intervention, the scientists say.
A
gene associated with the risk of schizophrenia regulates critical components of early brain development, according to a
new study led by researchers from Penn State University.
New research presented here yesterday at the annual meeting of the American Association for the Advancement of Science (which publishes ScienceNOW) finds that a
gene associated with increased risk of asthma is also linked to resistance against a parasitic worm.
The study found several
genes that are
associated with resistance to antibiotics, including
new genes that might point to previously unknown mechanisms of drug resistance.
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Gene variants modifying Huntington's symptom onset may lead to
new therapeutic strategies: Genome - wide association analysis identifies sites
associated with earlier - or later - than - expected symptom appearance in human patients.»
Although a healthy lifestyle and environmental factors can promote longevity, a
new genome - wide survey has ID'd
genes strongly
associated with living beyond the century mark
Using these
new imaging tools, scientists can now track how errant
genes associated with Alzheimer's behave.
For example, genetically engineered organisms used in the research laboratory to develop
new chemical synthesis methods are not likely to require the same level of public dialogue as products that have more uncertainty
associated with them, such as organisms with
gene drives, which enhance organisms» ability to pass certain genetic traits on to their offspring.
The study clearly shows the utility of the adeno -
associated virus in long - lasting
gene transfer, says molecular geneticist Rudolph Leibel, an obesity researcher at Columbia University in
New York City.
The genetic analysis revealed two
new IBD -
associated genes: PSMG1 and TNFRSF6B.
Researchers have shown that the
gene is
associated with vocal learning in young songbirds, which produce higher levels of FOXP2 protein when they need to learn
new songs.
New research findings from Uppsala University and Uppsala Clinical Research Center show that smoking alters several
genes that can be
associated with health problems for smokers, such as increased risk for cancer and diabetes.
A
gene associated with both protection against bacterial infection and excessive blood clotting could offer
new insights into treatment strategies for deep - vein thrombosis — the formation of a harmful clot in a deep vein.
In the
new study, the researchers examined the effects of
gene mutations known to be
associated with ASD in humans.
With every passing month now, scientists announce the discovery of
new genes and
gene neighborhoods that can be
associated with obesity.
A
new study led by researchers at Boston Medical Center (BMC) indicates that variations in opioid receptor
genes are
associated with more severe neonatal abstinence syndrome (NAS) in newborn babies.
The sorter then
associated capsid
genes with unfamiliar
genes — those considered
new, small or organized differently — that are unlikely to be produced by bacteria.
«This is the first study to show the actual cell behaviors caused by mutations in
genes causally linked to polycystic kidney disease, an important
new step in the path towards treatment,» said Dr. Robert L. Bacallao,
associate professor of medicine at the IU School of Medicine in Indianapolis.
Among the
gene variants modern humans inherited from Neandertals are ones
associated with higher cholesterol, increased belly fat, rheumatoid arthritis and schizophrenia, researchers learned from analysis of the
new Neandertal DNA.
The
new research focused on just nine
genes, those most strongly
associated with autism in recent sequencing studies, and investigated their effects using precise maps of
gene expression during human brain development.
Three simultaneous reports involving more than 32,000 participants uncovered four
new diabetes -
associated gene variants, bringing to 10 the number of known non-Mendelian genetic risk factors for type 2 diabetes.
By doing so they were able to identify two
new genes (COBL and SLC10A2)
associated with risk of AD in African Americans.
Now, to enable widespread
gene delivery throughout the central and peripheral nervous systems, Caltech researchers have developed two
new variants of a vector based on an adeno -
associated virus (AAV): one that can efficiently ferry genetic cargo past the blood - brain barrier; and another that is efficiently picked up by peripheral neurons residing outside the brain and spinal cord, such as those that sense pain and regulate heart rate, respiration, and digestion.
The
new finding is the latest evidence supporting a growing precision medicine model of psychiatric disease in which disruptions of certain
genes during brain development contribute to a person's risk for multiple psychiatric disorders, with other genetic or epigenetic drivers, random developmental events, or environmental influences determining the specific disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an
associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience at UCSF.
Specifically, the
new results boost knowledge about the effects of the viral vector used, adeno -
associated virus, which has been successfully used in
gene therapy for the eye since 2008.
However, since the novel
genes that were identified, are known to lead to aging -
associated diseases in humans, their further analysis seems to be promising for developing
new approaches to understand and possibly cure these diseases and to contribute to a long life and healthy aging in humans — in a way, long - lived rodents do.
The
new study suggests that even rare mutations that disable both copies of a
gene, which scientists thought would be
associated with diseases, aren't necessarily a problem.
With their
new draft in hand, Brand et al. searched the C. kruseigenome for
genes that are
associated with pathogenesis in the more familiar Candida albicans — the cause of thrush, vaginal yeast infections, and sometimes potentially lethal systemic infections.