For 1,317 distinct genes, both copies were found to have deleterious mutations in at least one individual, resulting in «human knockouts» for a remarkable number of
new genes for whom human knockouts have never been reported.
They went on to find
new genes for receptors sensitive to different wavelengths of light.
The researchers propose that the rapid evolution and wholesale remodeling of the Y chromosome in both species have been caused by several mechanisms, including the competitive advantage gained by developing
new genes for sperm production.
The effort has already had one practical result: the discovery of two
new genes for resistance to a race of wheat stem rust to which there is virtually no resistance in wheat.
But they also collected wild relatives of chickpeas in southeastern Turkey that hold «great promise,» von Wettberg says, as a source of
new genes for traits like drought - resistance, resistance to pod - boring beetles, and heat tolerance.
He notes that the Human Genome Initiative will increase the capacity to screen out undesirable traits «by identifying
new genes for carrier and prenatal testing, including, potentially, genes for alcoholism, homosexuality and depression.»
«
New gene for severe childhood epilepsy identified.»
«There's no question it's going to be a tremendous resource,» says Yale University's Judy Cho, who has used the HapMap to find
a new gene for Crohn's disease.
An international research team that includes the University of Melbourne's Professor Sam Berkovic (AC) has identified
a new gene for a progressive form of epilepsy.
Not exact matches
For a self - described bum off the streets of
New York,
Gene's — and the band's — success seems inevitable only in hindsight.
• Myonexus Therapeutics, a
New Albany, Oh. - based clinical - stage biotechnology company developing transformative
gene therapies
for limb - girdle muscular dystrophies, raised $ 2.5 million in seed funding.
• Calyxt, the
New Brighton, Minn. - based company based on
gene - editing foods, filed
for a $ 50 million IPO Friday.
These
new entrants would need to get a licensing agreement from Myriad
for anything they discovered related to the BRCA
genes, which would effectively shut down future work by anyone other than Myriad in this area.
Collectively, this
new kind of startup can help drive down the cost of
gene therapy discovery
for patients.
«Some of what they're doing borders on the edge of magic,»
Gene Russianoff, the staff lawyer
for a subway rider advocacy group, told the
New York Times» Matt Flegenheimer.
Approved treatments included
gene therapies and the first
new drugs
for rare diseases in many years.
Medical breakthroughs in 2018 range from
new devices
for sleep apnea to
gene therapy
for blindness, according to the Cleveland Clinic.
And a third, different kind of
gene therapy from Spark Therapeutics — to treat a rare inherited form of blindness — is likely to be approved by the end of 2017, too, making this year a landmark
for treatments that manipulate the body's own biological mechanisms in novel
new ways to fight deadly diseases.
Last month, Novartis AG (NOVN.S) won U.S. approval
for the first of a
new type of potent
gene - modifying immunotherapy
for leukemia, a $ 475,000 treatment that marks the start of a potential
new treatment paradigm
for some cancers.
Pfizer says it will also make some
new hires
for immuno - oncology and
gene therapy, two fields where it recently completed major deals.
«Customers are clamoring
for new and easy ways to interact with the organizations they deal with,» said
Gene Alvarez, Gartner's research vice president.
Angling to be the go - to marketplace
for these
gene - based businesses, Helix, the spin out from genetic testing research and technology giant Illumina, has held a first close on a planned $ 200 million funding round led by
new investor DFJ Growth.
By invalidating key parts of Myriad's patents, the court has removed a bar that prevented labs using
new technology from developing and selling broader one - time tests that search
for all known cancer risks, including the BRCA
genes, geneticists said.
The swearing in of 85 MLAs last week was a particularly joyous and awe - filled occasion
for the 70 who are brand
new to the Legislature, and a bitter - sweet one
for outdoing speaker
Gene Zwozdesky, 66,...
Risk Versus Reward: The Value of Cell Therapy
for Patients and Investors Source: Streetwise Reports (4/25/18) The cell therapy space, encompassing disruptive
new treatment including stem cell therapy, immunotherapy and
gene editing, has begun to mature, with a handful of product approvals and others in late - stage development.
Research on a
new «
gene editing» technology known as CRISPR — which theoretically allows any cell or organism to have its genome altered — is advancing exponentially, with early research ongoing on human embryos created
for that purpose.
*** The search
for a «gay
gene» may be off - target,
new research finds.
Even Walter Miller's A Canticle
for Leibowitz (1960) and
Gene Wolfe's The Book of the
New Sun (1980 - 83)-- serious and sympathetic explorations of religion — aren't centrally concerned with the survival of the Church.
«The event, the fourth of its kind, seeks to raise global awareness and create a forum
for collaboration around the wide array of powerful and promising cell therapies,
gene therapies, and immunotherapies emerging from medical institutions around the world, as well as the impact
new technology will have on humanity and society,» a press release by the Cure Foundation explains (h / t Christian Post).
[The search
for a «gay
gene» may be off - target,
new research finds.
It is, as well, an antidote to Mississippi Burning, a dishonest, award - winning
new film in which blacks wait patiently and fearfully in the background
for deliverance by two white FBI agents, played by
Gene Hackman and Willem Dafoe, who zealously bend the law in the interest of justice — a film one fears will have a profound effect on the way many Americans view their nation in the King Years («The Dream Dafoed,» as the Village Voice put it).
Due to my recent call
for blogs from readers of this blog, I recently started reading A Quest
for a
New Perspective, and I am loving what
Gene is writing there.
On the contrary, he finds it useful to ponder an array of reductionist attempts to explain the existence of religion, from that which seeks to pinpoint the area of the human brain or the specific
genes connected to religiosity to that which sees religion as a malfunction of the human mind or a vestigial remnant from a primitive stage of human development suitable only
for whimpering, immature dullards (a point of view championed by the
new atheists).
The principles that have emerged thus far are these: We should seek
new knowledge of our
genes (and we can say this without deciding whether the Human Genome Initiative is the wisest and most cost - effective way to do so) We should seek therapies
for the genetic disorders that afflict many people.
At the close of his essay
Gene Logsdon asks, «Could humankind
for once end an old cycle and begin a
new one based on a pastoral food system without an intervening decline or collapse of the economy and civilization?»
Therefore, the plants with
genes for superhot chiles had more offspring than the chiles with other parents.The mutation was discovered in 2016 by Dr. Peter Cooke of the
New Mexico State University Core University Research Resources Laboratory.
In retrospect, it was serendipitous that Dr. Garcia picked the pasilla, Colorado, and negro types; these types probably intercrossed and produced progeny that contained novel
gene combinations, allowing him to select
for the
new pod type and cultivar.
We are following international and national guidelines
for food safety of genetically modified crops, which require assessment of the nutritional value of Golden Rice and potential toxicity and allergenicity of proteins from the
new genes in it.
Data access and analysis tools are being made available
for the 3K RGP dataset through the International Rice Informatics Consortium (IRIC), which promotes collaboration in bioinformatics analysis of rice data and provides computational tools to facilitate rice improvement via discovery of
new gene - trait associations and accelerated breeding.
This massive dataset is a powerful resource
for understanding natural genetic variation in rice as well as
for large - scale discovery of
new genes associated with economically important traits.
Genetic modification can also greatly increase the accuracy of incorporating only those
genes for the needed trait into a
new rice variety.
Before the products from these varieties can be used, they will need approval from the Office of the
Gene Technology Regulator, which ensures GM plants are safe
for humans and the environment and from Food Standards Australia and
New Zealand which regulates food safety.
The EC has historically supported IRRI's work to conserve the genetic diversity of rice, understand the function of rice
genes, and develop
new rice varieties, particularly
for use in difficult growing environments.
Beyond this, the unique power of GM lies in its ability to incorporate novel
genes with useful traits
for rice, including
genes from plants and organisms unrelated to rice, into
new rice varieties that can not be achieved using other breeding methods.
A
new gene technology to differentiate between male and female chicks pre-hatch could improve animal production, reduce costs and eliminate ethical dilemmas
for the egg and poultry industries.
In 2012, at the Central Institute
for Cotton Research in Nagpur, I saw a
new variety of GM cotton carrying two so - called «stacked» Bt
genes in one test plot, while a nearby plot was testing a variety of cotton using organic methods —
for some farmers the premium prices
for organic cotton make it worthwhile.
The researchers identified several reasons
for this: The
new gene constructs interfere with the plant's own
gene for producing growth hormones, and the additional
gene constructs were not, as intended, active solely in the kernels, but also in the leaves.
Gene Stallings, the Cardinals»
new coach, may be best remembered
for the controversy he created while head coach at Texas A & M from 1965 to 1971.
(When
Gene Romero, the Honda team manager, asked Skip Eaken, a veteran mechanic
new to the Honda team, whom he wanted to work
for, Eaken replied, «I want Bubba.»)
We've been hearing about better male birth control
for years now, but in recent weeks two
new promising options have come to light: RISUG (reversible inhibition of sperm under guidance), being developed by an Indian scientist, Sujoy Guh, and the discovery of a
gene, Katnal1, critical
for sperm production; if scientists can tweak the
gene with a pill, sperm production will be stalled.