Sentences with phrase «new genetic drivers»

Not exact matches

The new finding is the latest evidence supporting a growing precision medicine model of psychiatric disease in which disruptions of certain genes during brain development contribute to a person's risk for multiple psychiatric disorders, with other genetic or epigenetic drivers, random developmental events, or environmental influences determining the specific disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience at UCSF.

An implicit assumption in the discipline of speciation biology is that genetic differences between populations of animals and plants in a given species are important drivers of new species formation and are a key to understanding evolution.

Will genetic engineering and biotechnical or nanotechnological manipulations become the new drivers of human evolution?

Using induced pluripotent stem cells (iPSCs), a team led by Mount Sinai researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver of risk for bone cancers, where the survival rate has not improved in 40 years despite treatment advances.

The reversal suggests that smaller changes in multiple genes may have been the primary driver of changes in human phenotypes, and that new models are needed to retrace the genetic steps of evolution.

Genetic rescue via GAL4 / UAS - DTH was also successful, although this required the generation of a new UAS - DTH1 transgene devoid of most untranslated regions, since existing UAS - DTH transgenes express in the brain without a Gal4 driver via endogenous regulatory elements.