New genome sequencing technologies provide insight into emerging artemisinin - resistance and a novel way to track this public health threat
Using
new genome sequencing technologies, the researchers discovered multiple strains of the malaria - causing parasite Plasmodium falciparum that appear to be rapidly expanding throughout the local parasite population in Western Cambodia, a known hotspot for drug resistance.
This work was carried out with funding from the Association for International Cancer Research (United Kingdom), the Lymphoma Research Foundation (USA) and the Instituto de Salud Carlos III (Spain), and illustrates how
new genome sequencing technologies are revolutionizing the study of different types of cancer.
Clues now revealed by
new genome sequencing.»
HiSeq X Ten,
a new genome sequencing machine lowers the cost of the sequencing process to $ 1,000.
A new genome sequence and powerful genetic tools promise to help crack their secrets
Since then,
each new genome sequenced and each new individual studied has illuminated our genomic landscape in ever more detail.
Not exact matches
• Gencove, a
New York - based
genome sequencing technology developer, raised $ 1 million in seed funding.
May 6, 2013 — Take a swab of saliva from your mouth and within minutes your DNA could be ready for analysis and
genome sequencing with the help of a
new device.
Evolution is not testable — Every
new fossil dug up, every
genome sequenced, every
new species discovered, every
new simulation run is a test of evolutionary theory.
This year, IRRI established a
new and relevant rice breeding factory, deciphered the information found in 3,000
sequenced rice
genomes, helped in marketing the Philippines» unique indigenous «heirloom» rice varieties to the outside world, distributed climate - smart rice varieties to reduce Asian farmers» risks, and celebrated 150 consecutive knowledge - filled cropping seasons of the Long - Term Continuous Cropping Experiment.
There was an ancient paradigm about the «fitness cost of antibiotic resistance,» but the emergence of the
new technologies of high - throughput
sequencing has changed the field, allowing researchers to study bacterial pathogenesis at the
genome scale,» said Dr. David Skurnik, senior author of a
new Bioessays article.
An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a
new technique for identifying gene enhancers —
sequences of DNA that act to amplify the expression of a specific gene — in the
genomes of humans and other mammals.
«Decoding the
genome's cryptic language:
New tool to map RNA - DNA interactions could help researchers translate gene
sequences into functions.»
In
new research, published in the journal FEBS Letters, scientists at the Quadram Institute carried out a search of the National Centre for Biotechnology Information's Whole
Genome Sequence database.
New DNA recovery and
sequencing technology is at last allowing scientists to assemble entire
genomes of ancient scourges — and elusive modern ones
Through detailed
genome comparisons,
sequence - alignment algorithms and other bioinformatics tools run on Los Alamos computers, the Los Alamos team identified features that differentiate among F. tularensis and other novel clinical and environmental Francisella isolates, providing a knowledge base for comparison of
new sequences from clinical or environmental surveys.
«Our work demonstrates that the generation of
genome sequences from a large number of archaic human individuals is now technically feasible, and opens the possibility to study Neandertal populations across their temporal and geographical range,» says Janet Kelso, the senior author of the
new study.
In the
new study, the researchers
sequenced the entire
genome of mice that had undergone CRISPR gene editing in the team's previous study and looked for all mutations, including those that only altered a single nucleotide.
Gene discovery was greatly facilitated by a
new exome
sequencing technology, which analyzes all protein - coding regions of the
genome at once.
And with the recent unveiling of the human
genome sequence — to say nothing of the
new drugs that are being tested every day — those working in the patent field are busier than ever.
Because evolution is conservative, the metric entropy of genomic data should increase as
new genomes are
sequenced.
Now Pääbo and his colleagues have devised a
new method of genetic analysis that allowed them to reconstruct the entire Denisovan
genome with nearly all of the
genome sequenced approximately 30 times over akin to what we can do for modern humans.
New methods for the removal of contaminating DNA from microbes and present - day humans that were developed by the Leipzig group have now enabled the researchers to
sequence the
genomes of five Neandertals from Belgium, France, Croatia, and Russia that are between 39,000 and 47,000 years old.
The
new method could unlock a wealth of untapped chloroplast
genome sequence data that can be applied to evolutionary studies.
The
new method by Garaycochea and colleagues will enable researchers to strategically analyze this whole -
genome sequence data and assemble the chloroplast
genome for their plant of interest.
«We explored the opportunity of using sperm RNA elements as a predictor of human health, with applications at the fertility clinic that would go hand - in - hand with the
new neonatal intensive care unit
genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and Development.
X-Woman A female finger bone from the Denisova cave in Siberia turned out to belong to a
new species when its
genome was
sequenced in 2010.
The
new peanut
genome sequences were released in 2014 to researchers and plant breeders around the globe.
A research team co-led by a scientist at
New Zealand's University of Otago has
sequenced the first complete mitochondrial
genome of a 2500 - year - old Phoenician dubbed the «Young Man of Byrsa» or «Ariche.»
The growth of publicly accessible data troves on
genome sequences, gene activity, and protein structures and interactions has opened
new territory for biologists.
In - depth analysis of the human body's microflora has been possible only in the past few years — a by - product of the same
new gene
sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human
genome.
The
sequenced genome can lead to improved molecular biology, physiology and neurobiology research in insects and also may help in developing future
new methods for insect pest management.
A recently completed
genome sequence of the
new virus has sped up efforts to come up with a diagnostic test to screen for it
For this purpose, the scientists combined a sophisticated bioinformatics strategy developed by Masaomi Hatakeyama that uses state - of - the - art
sequencing methods with a
new technology that can optically map the long, individual DNA molecules in the
genome.
Study collaborators included NIAID - funded scientists from Public Health Research Institute and
New Jersey Medical School - Rutgers University, as well as researchers from Case Western Reserve University, the Houston Methodist Research Institute and Hospital System and NIAID's Rocky Mountain Laboratories, where the comparative
genome sequencing took place.
«We wanted to provide these valuable data to scientists, and our hope is that this
sequenced genome will stimulate
new research in molecular studies of insects.»
A
new high - coverage DNA
sequencing method reconstructs the full
genome of Denisovans — relatives to both Neandertals and humans — from genetic fragments in a single finger bone
A
new study suggests that epigenetic effects — chemical modifications of the human
genome that alter gene activity without changing the DNA
sequence — may sometimes influence sexual orientation.
In the
new study, scientists from the NIH's National Institute of Allergy and Infectious Diseases (NIAID) and their colleagues sequenced the complete genomes of ST258 K. pneumoniae strains collected from two patients in New Jersey hospita
new study, scientists from the NIH's National Institute of Allergy and Infectious Diseases (NIAID) and their colleagues
sequenced the complete
genomes of ST258 K. pneumoniae strains collected from two patients in
New Jersey hospita
New Jersey hospitals.
The move comes in response to the announcement earlier this week of a
new U.S. company, launched by
sequencing - machine manufacturer Perkin - Elmer and J. Craig Venter of The Institute for Genomic Research, that plans a brute - force approach to
sequencing the human
genome within 3 years (ScienceNOW, 12 May).
After his group utilized a
new gene -
sequencing tool, they posted some unpublished
genome data online.
New genome -
sequencing research suggests white European people with two copies of variant forms of MC1R, a gene linked to pale skin and red hair, have faces that appear up to two years older than those who are the same age but don't have both copies.
«
Sequencing the human
genome, device miniaturization, and the advent of combination devices have shifted the focus from engineering to the life sciences in the device industry,» adds Jules Mitchel, president of Target Health Inc. in
New York City, a company that conducts clinical trials for MD&D companies.
The rationale for
sequencing and exploring the human
genome — to revolutionize the finding of
new drugs, diagnostics and vaccines, and to tailor treatments to the genetic make - up of individuals — is the same today.
Four countries — the United States, Canada,
New Zealand, and Australia — have already contributed a total of $ 53 million to
sequence the cow
genome, which, like its human counterpart, contains roughly 3 billion base pairs.
Today I'm working with scientists, physicians, and policy - makers on implementing
new HIV testing strategies, evaluating the adoption of
new hepatitis medications, and assessing the impact of
genome sequencing in society.
To reach this conclusion, Pääbo and his team spent years
sequencing the complete
genome of three Neanderthal bones from the Vindija Cave in Croatia and compared the results with the
genomes of five modern humans from southern Africa, West Africa, Papua
New Guinea, China, and Western Europe.
The advance might drop the cost of
sequencing a complete human
genome below $ 1000, which is expected to revolutionize personalized medicine and help usher in a
new era of genetic - based diagnostics and medicines.
A
new technique which colour codes DNA for laser
sequencing may offer a faster and cheaper way of
sequencing genomes compared with conventional methods.