There is a silver lining: Even stem cells that don't grow
into new heart cells seem to help patients in other ways.
The goal of stem cell therapy is to replace the damaged tissue
with new heart cells and restore the failing heart to normal function.
Studies have reported that stem cells can effectively support the heart not by
becoming new heart cells, but by releasing healing proteins, including ones that promote blood vessel growth.
The drug prompted mice to
make new heart cells and increased heart function by about 200 percent four weeks after a heart attack.
Because stem cells can turn
into new heart cells, scientists are looking at ways to inject them into damaged hearts.
The whole idea of stem - cell based therapies is that the stem cells could be used to replace or repair cells damaged or destroyed by disease or injury, such
as new heart cells for people who have had heart attacks or new neurons for patients with Alzheimer's disease.
December 17, 2012 — A study in mice suggests that
new heart cells arise from pre-existing heart cells and that the renewal process slows with age.
The next step proved even more promising: when we introduced these three genes into the injured hearts of living mice, we were again able to convert fibroblasts
into new heart cells, and these cells helped improve heart function, integrating with the old ones and beating in synchrony with the rest of the heart.