Sentences with phrase «new human genome»

«This is potentially the new Human Genome Project,» Karr said.

When Boeke met with Sc2.0 colleagues last summer to discuss their next target organism, San Francisco, California — based futurist Andrew Hessel of the software company Autodesk «sort of made this impassioned speech» for a new human genome project that would capture the public's imagination and inspire the field around a single goal, Boeke says.

But when she got an offer to start her own research group studying the evolutionary history of Latin Americans at Mexico's new human genome research institute, less than 3 years after finishing her Ph.D., she couldn't turn it down.

Not exact matches

J. Craig Venter, the superstar geneticist who mapped the first human genome in 2000, has a new challenge: decoding death.

Craig Venter, a biologist and entrepreneur as well as one of the first people to map the human genome, wants to make 100 the new 60.

Research on a new «gene editing» technology known as CRISPR — which theoretically allows any cell or organism to have its genome altered — is advancing exponentially, with early research ongoing on human embryos created for that purpose.

The principles that have emerged thus far are these: We should seek new knowledge of our genes (and we can say this without deciding whether the Human Genome Initiative is the wisest and most cost - effective way to do so) We should seek therapies for the genetic disorders that afflict many people.

He notes that the Human Genome Initiative will increase the capacity to screen out undesirable traits «by identifying new genes for carrier and prenatal testing, including, potentially, genes for alcoholism, homosexuality and depression.»

In a research paper published in April last year, Chinese scientists described how they were able to manipulate the genomes of human embryos for the first time, which raised ethical concerns about the new frontier in science.

«Our future in medicine and in health depends on understanding the information contained in the human genome, so it's a great topic for Science Week,» said Dr. Norma J. Nowak, Director of Science and Technology at UB's New York State Center of Excellence in Bioinformatics and Life Sciences.

Allison Mackay, commenting on The Scientist's story about a new, hand - held sequencer that can reportedly decode the entire human genome.

From the Building with Biology website: «The Building with Biology project team has received supplemental funding from the National Science Foundation to develop a new public forum on human genome editing called Editing our Evolution: Rewriting the Humane Genome.&genome editing called Editing our Evolution: Rewriting the Humane Genome.&Genome.»

«Our study shows that epigenetic drift, which is characterized by gains and losses in DNA methylation in the genome over time, occurs more rapidly in mice than in monkeys and more rapidly in monkeys than in humans,» explains Jean - Pierre Issa, MD, Director of the Fels Institute for Cancer Research at LKSOM, and senior investigator on the new study.

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

Diane Dickel is the lead author of Nature Methods paper describing a new technique for identifying gene enhancers in the genomes of humans and other mammals.

On average, every duplication of the human genome includes 100 new errors, so all that reproducing gave our DNA many opportunities to accumulate mutations.

«Our work demonstrates that the generation of genome sequences from a large number of archaic human individuals is now technically feasible, and opens the possibility to study Neandertal populations across their temporal and geographical range,» says Janet Kelso, the senior author of the new study.

We want to understand the basic mechanism underlying these multiple new copy number variant mutations in the human genome.»

And with the recent unveiling of the human genome sequence — to say nothing of the new drugs that are being tested every day — those working in the patent field are busier than ever.

Now Pääbo and his colleagues have devised a new method of genetic analysis that allowed them to reconstruct the entire Denisovan genome with nearly all of the genome sequenced approximately 30 times over akin to what we can do for modern humans.

New methods for the removal of contaminating DNA from microbes and present - day humans that were developed by the Leipzig group have now enabled the researchers to sequence the genomes of five Neandertals from Belgium, France, Croatia, and Russia that are between 39,000 and 47,000 years old.

Since the completion of the Human Genome Project in 2003, scientists have expanded their knowledge of how living cells work with new approaches including genomics, proteomics, and systems biology.

At a recent Biology of Genomes meeting, a biologist showed off a new method to extensively survey human cells for mysterious, sometimes gene - filled loops known as extrachromosomal circular DNA (eccDNA).

«We explored the opportunity of using sperm RNA elements as a predictor of human health, with applications at the fertility clinic that would go hand - in - hand with the new neonatal intensive care unit genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and Develophuman health, with applications at the fertility clinic that would go hand - in - hand with the new neonatal intensive care unit genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and DevelopHuman Growth and Development.

«We'd like to develop the resources so that people can quickly test hypotheses about the human genome by synthesising new versions.»

In - depth analysis of the human body's microflora has been possible only in the past few years — a by - product of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human genome.

Scientists poring over the 3 - billion - letter - long genomes of humans and mice made a host of new discoveries in 2005.

This avenue of research is still new, since we have only recently begun to decode the mysteries of the human genome, but studies are emerging every year.

A series of fine - tuned maps of DNA packaging in human cells reveal dynamic new views of how the genome's instructions are carried out to build a person.

Two years ago, human genome researchers broke with tradition and agreed to release new data on an ongoing basis (Science, 25 October 1996, p. 533).

«Gene variants modifying Huntington's symptom onset may lead to new therapeutic strategies: Genome - wide association analysis identifies sites associated with earlier - or later - than - expected symptom appearance in human patients.»

The National Human Genome Research Institute (NHGRI) in Bethesda, Maryland, forked over $ 25 million; the state of Texas, $ 10 million; the Canadian government, $ 5 million; and the governments of Australia and New Zealand, $ 1 million each.

A new high - coverage DNA sequencing method reconstructs the full genome of Denisovans — relatives to both Neandertals and humans — from genetic fragments in a single finger bone

Most drug companies seeking to apply the wealth of data on the human genome to the hunt for new drugs have turned to specialized start - up companies for help (Science, 7 February 1997, p. 767).

A new study suggests that epigenetic effects — chemical modifications of the human genome that alter gene activity without changing the DNA sequence — may sometimes influence sexual orientation.

The move comes in response to the announcement earlier this week of a new U.S. company, launched by sequencing - machine manufacturer Perkin - Elmer and J. Craig Venter of The Institute for Genomic Research, that plans a brute - force approach to sequencing the human genome within 3 years (ScienceNOW, 12 May).

«Sequencing the human genome, device miniaturization, and the advent of combination devices have shifted the focus from engineering to the life sciences in the device industry,» adds Jules Mitchel, president of Target Health Inc. in New York City, a company that conducts clinical trials for MD&D companies.

The rationale for sequencing and exploring the human genome — to revolutionize the finding of new drugs, diagnostics and vaccines, and to tailor treatments to the genetic make - up of individuals — is the same today.

Four countries — the United States, Canada, New Zealand, and Australia — have already contributed a total of $ 53 million to sequence the cow genome, which, like its human counterpart, contains roughly 3 billion base pairs.

In 1975, the notion of using recombinant DNA to design human babies was too remote to seriously consider, but the explosion of powerful new genome - editing technologies such as CRISPR - Cas9, zinc fingers, and TALENs has changed that.

Intriguingly, the new genetic resistance locus lies within a region of the genome where humans and chimpanzees have been known to share particular combinations of DNA variants, known as haplotypes.

They found that the Neanderthal genome shows more similarity with non-African modern humans throughout Europe and Asia than with African modern humans, suggesting that the gene flow between us and Neanderthals most likely occurred outside Africa as humans were en route to Europe, Asia, and New Guinea.

To reach this conclusion, Pääbo and his team spent years sequencing the complete genome of three Neanderthal bones from the Vindija Cave in Croatia and compared the results with the genomes of five modern humans from southern Africa, West Africa, Papua New Guinea, China, and Western Europe.

The advance might drop the cost of sequencing a complete human genome below $ 1000, which is expected to revolutionize personalized medicine and help usher in a new era of genetic - based diagnostics and medicines.

He founded a new company, Celera, and gambled on a «whole - genome shotgun assembly» approach, in which the 3 billion «letters» of human DNA would be fragmented, identified, and then put together in the correct order by computer.

Using these data, researchers identified four new markers of primary sclerosing cholangitis risk on the human genome, bringing the total number of known predisposing locations to 20.

«This study gives deep new insights into the life of a parasitic fluke in the human bile duct, and was enabled by the development of an exciting new genome assembly tool called OPERA - LG in our lab.

He pointed out that the new capabilities to precisely edit the genome has sparked off an intense debate in the USA and elsewhere, since the new precision tools could also be applied to modifying the genome in human germ cells or embryos.

Studies comparing the mouse and human sequences that accompany the mouse genome in the journal Nature suggest it provides plenty of new leads in biology and disease.

Careful attention to phenotyping diseases, facilitated by our knowledge of the human genome and computational analysis, has allowed observant physicians and physician - scientists to identify and categorize diseases in a manner that has informed basic science, given it new contexts, and in many instances provided important new directions for investigation.