Not exact matches
In The
Human Advantage: A New Understanding of How Our Brain Became Remarkable (MIT Press, 2016; 272 pages), neuroscientist Suzana Herculano - Houzel unravels what really sets the human brain apart from that of other primates, tracing our evolutionary history and describing her efforts to tally our individual neu
Human Advantage: A
New Understanding of How Our Brain Became Remarkable (MIT Press, 2016; 272 pages), neuroscientist Suzana Herculano - Houzel unravels what really sets the
human brain apart from that of other primates, tracing our evolutionary history and describing her efforts to tally our individual neu
human brain apart from that of other primates, tracing our evolutionary history and describing her efforts to tally our individual
neurons.
Waning production of
neurons and an overall shrinking of the dentate gyrus, part of the hippocampus thought to help form
new episodic memories, was believed to occur in aging
humans as well.
BRAIN CANDY A
new database offers a deep look at living
human nerve cells, revealing elaborate branching structures and myriad shapes, such as in this
neuron called a pyramidal cell (cell image, left and 3 - D computer reconstruction, right).
Researchers have identified the
neurons in monkeys that are dampened by scratching, a finding that could lead to
new ways of alleviating itching in
humans.
Recently, it was found that the
human hippocampus, linked with learning and memory, produces
new neurons throughout life.
For most of the past century the scientific consensus held that the adult
human brain did not produce any
new neurons.
A unique form of carbon dating, made possible by the Cold War, suggests that
new neurons rarely survive in the
human olfactory bulb after birth
Tufts University biomedical engineers recently published the first report of a promising
new way to induce
human mesenchymal stem cells (or hMSCs, which are derived from bone marrow) to differentiate into
neuron - like cells: treating them with exosomes.
The processors — modeled after the brain's networks of
neurons — are first trained by
humans on actual translations and then let loose on
new sets of data.
Given that in
humans HTR7 is also expressed in the
neurons that innervate the skin, this
new gene may well be responsible for itch in
human patients taking antidepressants.
Krainc and his colleagues showed this is due to differences in metabolism of dopamine between species, and underscored the importance of studying
human neurons to discover
new targets for drug development.
Some evidence exists already that
humans also repopulate their hippocampus with
new neurons, but data
Because mirror
neuron activity is thought to be a very basic part of brain function — and it can be seen in many animals besides
humans — the
new finding supports the notion that our brain is predisposed to distinguish «us versus them.»
The unsuccessful search for
new neurons in adult
human and monkey brains is disappointing to many.
The
new study — published October 18, 2016 in the journal Molecular Psychiatry — combined genetic analysis of more than 9,000
human psychiatric patients with brain imaging, electrophysiology, and pharmacological experiments in mutant mice to suggest that mutations in the gene DIXDC1 may act as a general risk factor for psychiatric disease by interfering with the way the brain regulates connections between
neurons.
Because neurogenesis surges in newborn mice and
humans and then tapers to a slow trickle by adulthood, Frankland and colleagues wondered if that explosion of
new neurons could help explain the widespread phenomenon of infantile amnesia — the inability of adults to remember events that occurred before they were 2 to 4 years old.
Caleb Finch, a neurobiologist who studies Alzheimer's at the University of Southern California in Los Angeles, points out that in
human brains, amyloid plaques are associated with
neuron death, which wasn't measured in the
new study.
After conducting studies in both
humans and mice, the researchers said this
new schizophrenia risk gene, called C4, appears to be involved in eliminating the connections between
neurons — a process called «synaptic pruning,» which, in
humans, happens naturally in the teen years.
Their
new paper, «Single - Cell Responses to Face Adaptation in the
Human Medial Temporal Lobe», has now been published in
Neuron.
If the
new mechanism also operates in the
human brain and can be potentiated, this could become of clinical importance not only for stroke patients, but also for replacing
neurons which have died, thus restoring function in patients with other disorders such as Parkinson's disease and Huntington's disease,» says Olle Lindvall, Senior Professor of Neurology.
In a
new study, published 11 August in Science, researchers classified
neurons from mouse and
human brain tissue by their methylation patterns.
For the
new study, the team used a cell - reprogramming technique (similar to those used to reprogram skin cells into stem cells) to generate
human DRG - type sensory
neurons from ordinary skin cells called fibroblasts.
Humans can make
new neurons, but only from specialised stem cells.
The study, «Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits,» which has been published in The Journal of Cell Biology, suggests potential
new strategies to stimulate the regrowth of
human neurons damaged by injury or disease.
If its claims hold, and future research reveals how crayfish blood cells are reprogrammed to become
neurons, it could offer
new therapeutic ways of doing the same with
human cells.
The ability of scientists to convert
human skin cells into other cell types, such as
neurons, has the potential to enhance understanding of disease and lead to finding
new ways to heal damaged tissues and organs, a field called regenerative medicine.
Researchers at the Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem — Inserm / AFM / UEVE), in collaboration with CNRS and Paris Descartes University, have recently developed a
new approach to better control the differentiation of
human pluripotent stem cells, and thus produce different populations of motor
neurons from these cells in only 14 days.
The
new approach will allow scientists to induce mature
human motor
neuron development in cell culture, and to identify the factors that are vital to that process, Wang said.
«If we can find a way to target those
neurons in
humans, maybe we can reduce the «high» produced by the drug and reduce the withdrawal symptoms,» said Olivier George, assistant professor at TSRI and senior author of the
new study.
Scientists have discovered a
new way to convert
human skin cells directly into motor
neurons (above).
Scientists working to develop
new treatments for neurodegenerative diseases have been stymied by the inability to grow
human motor
neurons in the lab.
More than 50 years later, scientists have found a way to use radioactive carbon isotopes released into the atmosphere by nuclear testing to settle a long - standing debate in neuroscience: Does the adult
human brain produce
new neurons?
He argues that
human survival may have depended not so much on our ability to produce
new neurons, but on our ability to keep old ones in order to accumulate memories over the entire lifespan.
After working to hone their technique for more than a decade, the researchers report that a small region of the
human brain involved in memory makes
new neurons throughout our lives — a continuous process of self - renewal that may aid learning.
These so - called bioreactors, and the mini-brains they foster, should open other
new and valuable windows into
human brain development, brain disorders and drug testing — and perhaps even produce
neurons for treatment of Parkinson's disease and other disorders, the investigators say.
Now, scientists from EPFL's Blue Brain Project in Switzerland, at the core of the European
Human Brain Project, and the Allen Institute for Brain Science in the United States, show in the July 24th edition of the journal
Neuron how a complex computer model is providing a
new tool to solve the mystery.
New research explains why so many biological networks, including the
human brain (a network of
neurons), exhibit a hierarchical structure, and will improve attempts to create artificial intelligence.
A
new study takes a comparative approach to pinpoint what happens differently in
humans versus other animals to explain why they can successfully regenerate
neurons while we instead form scar tissue.
AMSBIO has introduced a
new range of neural progenitor cells, and cerebral cortical
neurons, derived from
human induced pluripotent stem (iPS) cells.
The
human hippocampus creates
new neurons throughout a person's lifetime — but most scientists thought that this process, called neurogenesis, does not happen as readily to older people past middle age.
Using 14C dating we could show that the generation of
new cardiomyocytes and
neurons in
humans is not restricted to development but instead continues throughout life (Bergmann et al., 2015; Spalding et al., 2013).
Waning production of
neurons and an overall shrinking of the dentate gyrus, part of the hippocampus thought to help form
new episodic memories, was believed to occur in ageing
humans as well.
These mice developed hallmark signs of PD in their brains and behavior: loss of dopaminergic
neurons in the SNc, impaired generation of
new neurons in one of the few regions capable of producing them in adult organisms, and impaired muscle coordination similar to
human victims of Parkinson's (as evidenced by difficulty in rearing up on their hind legs)(Figure 2).
The team used genetically engineered mice to study the effects of different
human apoE variants on the maturation of neural stem cells or progenitor cells, from which
new neurons develop in the adult brain.
We are using a
new technique, called single cell RNA sequencing, to isolate thousands of single
neurons from
human brain tissue, study all the genes that are expressed in each individual cell, and make cell - to - cell comparisons between normal, early stage and late stage AD.
This
new ADSP study of connectomes maps the connections of every
neuron in the brain, whether
human or mouse.
Oct. 17, 2016 —
New Associate Professor of Psychology Suzana Herculano - Houzel produced the first accurate count of the number of
neurons in the
human brain — 86 billion, making it simply an enlarged primate brain.
Just like a younger brain, the aging
human brain can still form
new neurons but why does the brain deteriorate in old age?
In a
new study, released on bioRxiv as an online pre-print, Pollard and her colleagues tested the function of over 700 HARs in early - stage
human and chimpanzee
neurons.
Yang Xiang, PhD, assistant professor of neurobiology at University of Massachusetts Medical School, has received a three - year, $ 900,000 grant from the
Human Frontiers Science Program to lead an international team of scientists, including Gang Han, PhD, assistant professor of biochemistry & molecular pharmacology, in the development and implementation of a
new optogenetic platform that can remotely activate
neurons inside a free - moving organism.