Sentences with phrase «new issue of nature»

At the same time, Ehret and Chakravarti were also involved in another of the studies reported in the new issue of Nature Genetics.

Not exact matches

The first step in regulating such a new industry, Musk said, is «to learn as much as possible, to understand the nature of the issues.»

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward - looking statements include, among others, the following: our ability to successfully and profitably market our products and services; the acceptance of our products and services by patients and healthcare providers; our ability to meet demand for our products and services; the willingness of health insurance companies and other payers to cover Cologuard and adequately reimburse us for our performance of the Cologuard test; the amount and nature of competition from other cancer screening and diagnostic products and services; the effects of the adoption, modification or repeal of any healthcare reform law, rule, order, interpretation or policy; the effects of changes in pricing, coverage and reimbursement for our products and services, including without limitation as a result of the Protecting Access to Medicare Act of 2014; recommendations, guidelines and quality metrics issued by various organizations such as the U.S. Preventive Services Task Force, the American Cancer Society, and the National Committee for Quality Assurance regarding cancer screening or our products and services; our ability to successfully develop new products and services; our success establishing and maintaining collaborative, licensing and supplier arrangements; our ability to maintain regulatory approvals and comply with applicable regulations; and the other risks and uncertainties described in the Risk Factors and in Management's Discussion and Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10 - K and our subsequently filed Quarterly Reports on Form 10 - Q.

As I outline in a new paper out in the January 2016 issue of Nature Biotechnology, titled «This Time May Be Different», there's a strong case to be made that indeed this time is different.

Given the absence of a public trading market of our common stock, and in accordance with the American Institute of Certified Public Accountants Accounting and Valuation Guide, Valuation of Privately - Held Company Equity Securities Issued as Compensation, our board of directors exercised reasonable judgment and considered numerous and subjective factors to determine the best estimate of fair value of our common stock, including independent third - party valuations of our common stock; the prices at which we sold shares of our convertible preferred stock to outside investors in arms - length transactions; the rights, preferences, and privileges of our convertible preferred stock relative to those of our common stock; our operating results, financial position, and capital resources; current business conditions and projections; the lack of marketability of our common stock; the hiring of key personnel and the experience of our management; the introduction of new products; our stage of development and material risks related to our business; the fact that the option grants involve illiquid securities in a private company; the likelihood of achieving a liquidity event, such as an initial public offering or a sale of our company given the prevailing market conditions and the nature and history of our business; industry trends and competitive environment; trends in consumer spending, including consumer confidence; and overall economic indicators, including gross domestic product, employment, inflation and interest rates, and the general economic outlook.

We talked about those tech areas, some newer arenas Aspect is eyeing such as artificial intelligence, voice, and blockchain — as well as issues such as international competition, diversity, potential effects of trade sanctions on startups, and the changing nature of entrepreneurs themselves.

Still, given the new nature of the testnet, developers have been quick to suggest a range of possible issues and fixes that could once again see a jumpstart in activity.

The March 12, 2015 issue of Nature magazine contains an essay — not an original thesis, rather a summation — by two English geographers entitled «Defining the Anthropocene,» the subject of which is whether (and starting when) human activity has so altered the global environment as to constitute a new geologic age: the Anthropocene Age, as successor to the 11,000 - year Holocene Epoch that is itself part of the larger 2.6 million year - old Quaternary Period (or Great Ice Age).

He rarely «joined issue»; it was more of his nature to give the course of shared thought a sudden turn into some new dimension» nearly always surprisingly, always relevantly....

Neoconservatives differed with traditional conservatives on a number of issues, of which the three most important, in my view, were the New Deal, civil rights, and the nature of the Communist threat.

Tommy God has already forgiven you for your sin the moment you asked Jesus into your life and confessed him as Lord.From that point he paid for your sin in full past present future.It is not sin that stops us from being with the Lord so you are saved.The problem you are experiencing is the battle for your life in the here and now satan is out to destroy you and he knows our weaknesses.If you are honest there were already issues in your life that you struggled with and never got the victory over.So where do you go from here as i found myself in the same situation i was a christian but walking according to the flesh.God does nt change his mind he always loves us but because of our choices we distance ourselves from God.The issue is that we like sin thats our wicked hearts and to be fair we cant change our nature only Christ can do that our old nature must be crucified with Christ.The stumbling block is our pride we have to admit that we cant do it For me that was terribly difficult i was so independent thinking i could do anything but the truth was a made a real mess of things.I sense you are at a crossroads and are feeling desperate and confused.So as a brother in the Lord you need to confess your sin to God and tell him that you are weak -LCB- we all are -RCB- and that you cant do it in your strength -LCB- None of us can -RCB- but ask him to send the holy spirit to help you deal with the temptations and the sin that you struggle with and he will help you to change your life he will empower you as he did me.Rather than look at who you are look to Christ and walk in him and he will make you a new man and sin will not have dominion over you.Jesus came to set us free from bondage.Having once been a slave to sin i know what it is like to have been set free by the power of God and that is what Christ is offering you today.All it takes is a desire to change or repent and admit we cant do it and trust him to give you the strength to walk in him regards brentnz

However, I once saw Harvey Mansfield on C - Span speak of the issue of nature in regards to the city of New Orleans and the hurricane Katrina.

The impact of a biomedical revolution raises new issues about sexual practices, the nature of conception and childbearing, and the meaning of marriage and parenthood.

8 He has raised the issue of the nature of man and has asked whether the New Testament when viewed solely as content or solely as address has a message capable of redeeming the whole man.

The authority of the Nicene Creed follows from this Protestant principle of the perspicuity of Scripture because this principle leads us to think that the early Church, when faced with the need to explicate more precisely the identity and nature of Christ, would get it right, given the obvious importance of this issue in the New Testament revelation.

However, as in the seventeenth century the various later theories were not produced independently of each other but came to be developed by working through, and in divergence from, the first great attempt at a philosophical structure built upon a profound insight into the problems at issue, namely, that of Descartes, so in our time the new efforts which are required in the philosophy of nature will need to come to terms with the pioneering work of Whitehead.

In doing so, we will be able to provide a new basis for discussion of the relationship of science to religion and of the issue of nature and purpose.

She quotes from the teachings of the Catholic Church, such as Gaudium et Spes, on a whole range of issues from the sacramental nature of marriage to theimportance of the being open to new life.

We actually created the fix for these issues really quite quickly, but the nature of the fix was a server configuration change that was non-trivial to implement, and took us a whole long weekend to work out and deploy on a brand - new platform.

It would appear that the Alliance is in a somewhat complex situation in that its new Strategic Concept clearly sets out energy security in its mission, but that the two issues of this nature that are of greatest concern to its members — the reliability of oil and natural gas and the stability of the energy markets — fall under other institutions, which are better able to deal with these issues.

Upon learning of this, Erie County immediately contacted New York State and commenced an investigation into the nature of these payments to learn if they were made erroneously or were being issued as part of the Richard C. v. Berlin lawsuit settlement, which grants a one - time SNAP benefit payment to certain eligible recipients affected by that lawsuit.

While the Rockland County Times certainly can not claim credit for our President's «change of heart» on this vital issue, the many weeks of articles that the Rockland County Times devoted to explaining the critical nature of this project, which will bring many thousands of high - paying jobs into the New York - New Jersey Metropolitan Area as well as provide a much - needed «ONE - SEAT» train ride from Rockland County directly into Penn station, might have had some small influence on this favorable outcome!

Seminar Will Address Mold Issues in the Home The Oneida County Health Department, in conjunction with the New York State Department of Health (NYSDOH), will hold a seminar to educate the public on the nature and causes of mold in the home, its impact on health, and the proper methods of remediation, Phyllis D. Ellis, Oneida County Director of Health, announced today.

The versatile gels, described in this week's issue of Nature, could lead to new tools for diagnosing illness, flagging environmental hazards, and monitoring industrial processes.

This special issue addresses modern developments in controlling and manipulating light: how light - based technologies are shrinking and becoming faster (Koenderink et al., p. 516); how recent theoretical developments in the manipulation of light are being implemented to provide materials with properties not available in nature (Pendry et al., p. 521); how the quantum properties of light are being exploited in new technologies (Walmsley, p. 525); and how new light sources are coming online that can probe the structure of matter on spatial and time scales that provide an exquisitely detailed picture of our microscopic world (Miao et al., p. 530).

Pentelute is the senior author of a paper describing the new system in the Feb. 27 issue of Nature Chemical Biology.

Experts say the new fullerene, described in tomorrow's issue of Nature, may be easier to fashion into everything from high - temperature superconductors to high - strength materials.

But a new finding, reported in the March issue of Nature Medicine, indicates that this protection is not absolute.

The new study, reported in the 6 February issue of Nature, shows that hydrothermal plumbing is quite capable.

To build their transistor, Jan Hendrik Schn of Bell Laboratories in New Jersey and colleagues, who describe their findings in the current issue of the journal Nature, allowed many thousands of organic molecules to assemble themselves onto a gold film like bristles on a brush.

A paper published online in the 27 January issue of Nature shows that people on ARVs who appear to completely suppress the virus in their blood have new HIV being made in their lymph node cells — which may be refilling the reservoir.

In the online issue of the journal Nature, the researchers report a new function of FAM134B in the constant renewal of the endoplasmic reticulum (ER), an important cell organelle.

The finding, reported in next month's issue of Nature Medicine, raises new questions about whether people could contract exotic diseases if animal organs become routinely transplanted into human patients.

But help may be on the way: Scientists report in next month's issue of Nature Medicine that rats unable to digest lactose, a sugar in dairy foods, are cured by a pill that stitches new genes into the cells of the gut.

In a comment published in the same issue of Nature, archaeologist Erella Hovers of The Hebrew University of Jerusalem takes a cautiously positive view of the new findings.

Now, a trio of studies in the July issue of Nature Medicine opens new avenues for plaque research by presenting a new animal model for plaque formation, a diagnostic tool for spotting them, and a possible way to break them down.

The new material has a refractive index of 1.05, the team reports in the March issue of Nature Photonics, the lowest ever reported for a thin film.

The new work, described in the 20 December issue of Nature, may eventually shed light on facial deformities in people, enhancing prevention and treatment.

That's not the case with the new cluster, reported in the 13 June issue of Nature by planetary scientist David Nesvorný of the Southwest Research Institute in Boulder, Colorado, and his colleagues.

«Instead of consuming all bacteria in their patch, [the amoebae will] stop feeding early and incorporate bacteria into their fruiting bodies,» wrote the researchers in a new paper, published in the January 20 issue of Nature.

The new work, reported online in the 28 February issue of Nature, modifies the Cas9 enzyme, creating at least four times as many potential docking sites.

In a study described in the January 28 issue of Nature Neuroscience, the Hopkins team describes this new gene control mechanism and how it may contribute to Rett Syndrome, a nervous system disorder affecting mostly girls that causes problems with movement and communication.

The finding, published in the current issue of the journal Nature Communications, could lead to new therapies for treating a common sub-type of GBM and possibly other forms of cancer.

Lee's study results, which appear in the July 16, 2015 issue of Nature Communications, revealed new understanding about how 14 -3-3 sigma — a cell cycle «controller» - regulates cancer metabolic programming, thus protecting healthy cells from turning into tumor - producing factories.

The new t - ray laser, described in the 9 May issue of Nature, is only about 10 micrometers thick, or a tenth the width of a human hair.

The advance, described in next month's issue of Nature Biotechnology, could lead to more accurate screening of organ donors and identification of genetic targets for new drugs.

The work was done by Jens Kremkow and collaborators in the laboratories of Jose Manuel Alonso at the State University of New York College of Optometry and will be published in the May 5, 2016 issue of Nature.

Published in the August 2015 issue of Nature Medicine, the new findings show that a small molecule called N1 - methylnicotinamide prevents metabolic complications caused by a high - fat diet.

The new device, described in today's issue of Nature, should be easy to manufacture and could eventually provide a cheap alternative to magnetic hard drives and other storage media.