Sentences with phrase «new laboratory models»

NCI's efforts to develop new laboratory models of human cancer includes vastly increasing the number of human cancer cell lines (grown as two - dimensional and three - dimensional cultures) and patient - derived tumor xenografts.

Not exact matches

Just as Silicon Valley companies are laboratories for new technologies and business models, so Toms is becoming a kind of Darpa for the social - venture set.

Some football helmet manufacturers suggest that players who wear their helmets - especially new models - may be at lower risk of concussion than those who wear competitors» models or older helmets, basing their claims on how well the new or newer helmets absorb and lessen some of the impact forces that cause concussion in biomechanical studies performed in the controlled environment of the laboratory.

The new model «came out of left field, but it's very original,» says materials scientist Graham Hubler of the Naval Research Laboratory in Washington, D.C., who saw ball lightning as a teenager during a thunderstorm in upstate New York 40 years anew model «came out of left field, but it's very original,» says materials scientist Graham Hubler of the Naval Research Laboratory in Washington, D.C., who saw ball lightning as a teenager during a thunderstorm in upstate New York 40 years aNew York 40 years ago.

«Where this model really shines is explaining the late emission,» says Chris Fryer of Los Alamos National Laboratory in New Mexico — one of the physicists who first proposed the burrowing black hole theory in the 1990s.

Using geological observation, laboratory impact experiments and computer modeling, Schultz and Brown graduate student Stephanie Quintana have offered a new explanation for how those streaks were formed.

Realistic stem cell therapies to replace diseased or damaged tissue may still be years away, but researchers have uncovered a promising new use for these undifferentiated cells: they can be programmed to become patient - specific laboratory models of inherited liver disease.

But Chris Fryer, a theoretical astrophysicist at Los Alamos National Laboratory in New Mexico, says it is more likely that the standard afterglow model needs revision.

The scientists then tested three new mTOR inhibitors currently under development (pp242, AZD8055 and INK128) in combination with the chemotherapies AraC, Etoposide and Cisplatin to see how they affected laboratory lines of leukemia cells and mouse models of the disease.

The menagerie of exoplanets has provided new natural laboratories for scientists to test out models of planetary formation and evolution.

Modeled on such pathbreaking establishments as the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom, and Bell Labs in New Jersey, Janelia consists of small, multidisciplinary groups — approximately 45 of them when staffing reaches full strength in 2009.

To gain new insights, Luther Bartelt of the University of North Carolina at Chapel Hill and colleagues developed a new laboratory mouse model of co-infection during malnutrition.

In his groundbreaking book The Inflationary Universe, for example, Alan Guth of MIT, who codeveloped the leading model of the Big Bang, speculates provocatively about whether it would be possible to create a new universe in a basement laboratory, but he treats such a Genesis - on - demand merely as a scientific thought problem.

Today, a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Partha Mitra describes a new mathematical model that combines large data sets to predict where different types of cells are located within the brain, based on their molecular identity.

Now Lawrence Berkeley National Laboratory (Berkeley Lab) researchers have extended cryo - EM's impact further by developing a new computational algorithm that was instrumental in constructing a 3 - D atomic - scale model of bacteriophage P22 for the first time.

A team led by Charles R. Carrigan at Lawrence Livermore National Laboratory (LLNL) used field experiments to build a new, complex model that predicts isotopic ratios of noble gases that would be released from such explosions (Sci.

And finally, after decades of work developing theoretical models and computer simulation techniques, along with laboratory experiments to reproduce new molecules, astrochemists are putting names to many of those unidentified lines.

The puzzle of just how a fly ball is tracked and caught had been explored before — as long ago as the 1960s — by a professor of aeronautics at the Cornell Aeronautical Laboratory in Buffalo, New York, who had come up with a theory known as the Optical Acceleration Cancellation model, or OAC.

«This new high - resolution climate model is able to simulate regional - scale precipitation with considerably improved accuracy compared to previous generation models,» said Tom Delworth, a research scientist at NOAA's Geophysical Fluid Dynamics Laboratory in Princeton, N.J., who helped develop the new model and is co-author of the paper.

Today, Cold Spring Harbor Laboratory (CSHL) and The Lustgarten Foundation jointly announce the development of a new model system to grow both normal and cancerous pancreatic cells in the lLaboratory (CSHL) and The Lustgarten Foundation jointly announce the development of a new model system to grow both normal and cancerous pancreatic cells in the laboratorylaboratory.

The new computational model is built on CogSketch, an artificial intelligence platform previously developed in Forbus» laboratory.

Physicists at the U.S. Department of Energy's (DOE) Princeton Plasma Physics Laboratory (PPPL) have helped develop a new computer model of plasma stability in doughnut - shaped fusion machines known as tokamaks.

A new integrated climate model developed by Oak Ridge National Laboratory and other institutions is designed to reduce uncertainties in future climate predictions as it bridges Earth systems with energy and economic models and large - scale human impact data.

As DOE laboratories have gradually hired talented staff away from NCAR, another concern was that a new model would vacuum up valuable expertise that otherwise was needed for model development.

«We desperately need new therapies for this disease, and regenerative medicine approaches have shown great promise in laboratory models and in clinical trials for other conditions.»

According to the authors of the study, in future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden preclinical studies with laboratory animal models.

«It sure does look like the standard model Higgs boson, you bet,» says Sally Dawson, a theorist at Brookhaven National Laboratory in Upton, New York, who was not involved with the measurements.

The European Molecular Biology Laboratory is teaming up with the Spanish government to create a new center for the development of mathematical models of living systems.

Researchers at MIT's Computer Science and Artificial Intelligence Laboratory have developed a new computational model of a neural circuit in the brain, which could shed light on the biological role of inhibitory neurons — neurons that keep other neurons from firing.

A new study shows that restoring the lipids that help keep lung tissue flexible and inflated can help slow disease progression in laboratory models of pulmonary fibrosis.

Research teams are also developing ways to innovate the early drug - discovery process, including pioneering methods to rapidly identify drug targets and test them on laboratory models and finding and testing new therapeutic possibilities for already FDA - approved drugs.

This session examined the biogeochemical processes that are likely to affect the evolution of the Earth system over the coming decades, with a focus on the dynamics of marine and terrestrial ecosystems and the development of improved understanding through (a) fieldwork and laboratory experiments, (b) development of new observational datasets, both modern and palaeo, and (c) simulations using numerical models.

This unique research model brings together four laboratories, each with a specific skill, to work together to discover new biomarkers.

Congratulations to Umrao Monani, Assistant Professor at the Motor Neuron Center of Columbia University and Cathleen Lutz, Associate Director of Genetic Research Science at The Jackson Laboratory, and their colleagues for their new publication «Postsymptomatic Restoration of SMN Rescues the Disease Phenotype in a Mouse Model of Severe Spinal Muscular Atrophy» in the Journal of -LSB-...]

March 13, 2007 — Cold Spring Harbor, New York — RNA splicing antisense technology studied at Cold Spring Harbor Laboratory (CSHL) effectively corrected an mRNA splicing defect found in spinal muscular atrophy (SMA) patients, and is now ready to be tested in mouse models.

«To move beyond cataloging microbes, we will need new tools to rapidly determine microbial gene function and monitor the chemicals microbes use to communicate and interact with their environment, and new ways to visualize and model those interactions,» said Eoin Brodie, a staff scientist at Lawrence Berkeley National Laboratory's Earth Sciences Division and an author of the proposal.

The Microbiology Services Division at Porton Down, part of the National Infection Service directorate, has extensive high - containment laboratory facilities and rare capabilities to handle infectious organisms under the highest levels of containment, and the ability to work with in vivo models to evaluate new therapeutic interventions against these organisms.

«But the timing was optimal; when the new DNA sequencing machines were unpacked at our newly established laboratory, DNA arrived from our model spruce tree.

The Jackson Laboratory celebrated the groundbreaking for its new, state - of - the - art vivarium, a 134,900 - square - foot facility to maintain research mouse models, at the institution's Ellsworth, Maine, location on August 2.

Professional Experience 1983 — 1986 Research / Teaching Assistant, Exercise Physiology, University of Texas, Austin TX 1986 — 1990 Assistant Instructor / Research Assistant, Cell Biology, Developmental Biology, and Vertebrate Physiology, University of Texas, Austin TX 1993 — 1994 Visiting Assistant Professor, Department of Animal Sciences, Oregon State University 1994 — 1996 Technical Services Advisor, Genetic Resources, The Jackson Laboratory, Bar Harbor ME 1996 — 1998 Manager, Technical Services, The Jackson Laboratory, Bar Harbor ME 1997 — 1998 Assistant Professor, Adjunct, New Mexico Highlands University, Las Vegas NM 1998 — 2000 Senior Technical Information Scientist, The Jackson Laboratory, Bar Harbor ME 2000 — 2002 Senior New Models Development Scientist, The Jackson Laboratory, Bar Harbor ME 2002 — 2004 Associate Director of Genetic Resources, The Jackson Laboratory, Bar Harbor ME 2004 — 2005 Associate Research Scientist, The Jackson Laboratory, Bar Harbor ME 2004 — 2009 Assistant Professor, Dept. of Biology, New Mexico Highlands University, Las Vegas NM 2009 — 2014 Associate Professor, Dept. of Biology, New Mexico Highlands University, Las Vegas NM 2014 — present Professor, Dept. of Biology, New Mexico Highlands University, Las Vegas NM

In close collaboration with Dr. Yamanaka Dr. Conklin's laboratory was able to establish new iPS cell disease models, gain new insights into iPS cell biology, and develop new tissue engineering methods.

Methods: As reported in Geophysical Research Letters, the team led by scientists from PNNL and the National Oceanic and Atmospheric Administration's Atlantic Oceanographic and Meteorological Laboratory used both observations and models to derive their new formula.

In one sentence: Scientists at Pacific Northwest National Laboratory determined that high concentrations of nitrogen oxides influence the creation of the brown haze that hangs over the world's megacities, providing new insights that can create higher accuracy climate and atmospheric models.

But it's such a new way of thinking about it and we're getting really, really encouraging results in our laboratory models,» said Peter Brooks, a senior scientist with MMCRI.

PHENOMIN - ICS is also a key player in the development and the characterisation of new mouse models for many academic laboratories or big pharmaceutical groups, and contributes to European and international leading projects.

These findings are forming the basis for new laboratory studies aimed at identifying the chemical pathways they can implement in models.

Now Lawrence Berkeley National Laboratory (Berkeley Lab) researchers have extended cryo - EM's impact further by developing a new computational algorithm that was instrumental in constructing a 3 - D atomic - scale model of bacteriophage

Through «heart - on - a-chip» technology — modeling a human heart on an engineered chip and measuring the effects of compound exposure on functions of heart tissue using microelectrodes — Lawrence Livermore National Laboratory (LLNL) researchers hope to decrease the time needed for new drug trials and ensure potentially lifesaving drugs are safe and effective while reducing the need for human and animal testing.

Michael Sramek, a former summer intern at the Gladstone Institutes, and Yvanka de Soysa, a graduate student in the laboratory of Deepak Srivastava, MD, worked together to develop a new mouse model of heart disease.

In addition to research on rhabdomyosarcoma, the Ignatius laboratory has also generated new syngeneic zebrafish models of aggressive Malignant Nerve Sheath Tumors and hemangiosarcomas for which there are no effective treatments.