Conclusions: We thus developed an FGF2 - induced model of human β - cell dedifferentiation, identified
new markers of dedifferentiation, and found evidence for increased pancreatic FGF2, FGFR1, and β - cell dedifferentiation in T2D.
Similar experiments could identify
new markers of diseased tissue or new targets for targeted molecular therapies.
Using these data, researchers identified four
new markers of primary sclerosing cholangitis risk on the human genome, bringing the total number of known predisposing locations to 20.
«Therefore, urinary 8 - oxoGsn is promising as
a new marker of aging.»
This new marker of senescent cells is recognized by a naturally occurring IgM antibody that belongs to the innate immune system and is likely to be involved in a natural mechanism of immune recognition and clearance of senescent cells.
Not exact matches
The Trump Organization has ordered a set
of golf course
markers emblazoned with the presidential seal, raising questions about whether its use
of them is illegal, according to a
new report.
Carlyle shares were up marginally by 0.5 percent at $ 20.60 in afternoon trading in
New York, giving it a
marker capitalization
of $ 7 billion.
Continuing with the whiteboard example, many people asked me why we didn't go with one
of those fancy
new «smartboards,» workplace tools that use touchscreen technology instead
of dry erase
markers and can print out what you've written on them.
In the case
of XRP is a brand
new Blockchain — this is not an add
marker ERC - 20 is relatively trivial.
The
new research has the potential to be used by the bakery sector to allow for more accurate testing for the presence
of these
marker proteins, thereby identifying so - called «hidden allergens».
We use
new approaches for increasing yield potential, such as
marker - assisted breeding to develop the next generation
of rice varieties suited for irrigated environments in Asia.
On Monday, Nov. 9, the foodie fun continues with a Wild Game Dinner featuring beer pairings by Wood Boat Brewery, kicking off at 6 p.m.The seven - course menu consists
of Wild Boar Belly Salad and Pardon Me Pale Ale; Grilled Pheasant and Burrville Hard Apple Cider; Blackened Rabbit Saddle with Quail Egg Bearnaise and Channel
Marker IPA; Golden Beet Gelato with Mascarpone and Poppyseed; Reisling - Braised Venison Shank and Oatmeal Stout; Elk Loin with Stone Ground Mustard Reduction and Cherry Wheat Ale; and Candied Duck Prosciutto with
New York Maple Ice Cream and Punkin» Wheat Ale.
Watching my milk hit the first
marker, the second and so on was like scrolling through Netflix and seeing
new seasons
of all your favorite shows: satisfying, soothing, and oh - so - seductive.
While some studies have looked at outcomes much later in life, this
new study is the first to assess how breastfeeding affects
markers of heart health in younger and middle - aged women, about a decade after having children.
A
new study
of 635 children in Massachusetts found that a bigger waist size at age 3 increases the odds that a child will have a
marker for liver damage and nonalcoholic fatty liver disease by age 8.
He pointed to the January opening
of the Second Avenue Subway, and the ongoing revamps
of John F. Kennedy Airport and LaGuardia Airport as
markers of a push towards major
new infrastructural development.
They might find it impossible to buy
new furniture because otherwise the bank accounts
of the furniture
marker would be closed by the bank because otherwise the bank could no longer trade in the US.
«Perhaps we can all look to this decade
marker as the beginning
of a
new era.»
New York State Environmental Conservation Law (subdivision 1
of section 33 - 1004) requires individuals who apply lawn care pesticides to their residential properties within Erie County to post visual notification
markers along the perimeter
of any treated area
of over 100 square feet.
Members
of New York's political class see the 59 - year - old governor as carefully laying down
markers for his future, whatever it may hold, after Clinton's unexpected defeat.
More happily for the
new PM, the share is above the success
marker of 40 %.»
Cuomo's comments came a day after Mayor de Blasio's monuments commission decided that the statue
of Columbus in Columbus Circle and other monuments around the city should remain where they are but be adorned with
new historical
markers.
Over the past two years, the state department
of transportation says they've placed
new pavement markers, signs, and other devices at train stations in New Castle, Mount Kisco, White Plains, and even on Lakeview Avenue in Valhal
new pavement
markers, signs, and other devices at train stations in
New Castle, Mount Kisco, White Plains, and even on Lakeview Avenue in Valhal
New Castle, Mount Kisco, White Plains, and even on Lakeview Avenue in Valhalla.
Yesterday's events in
New York will surely go down as yet another
marker in the state's history
of political corruption as six officials, including former
New York State Senate Majority Leader, State Senator Malcolm Smith, are now facing federal charges.
Through a
new study
of the coccobacillus Francisella, Los Alamos National Laboratory researchers are working to use DNA
markers to discern related but relatively harmless species as they are identified and to provide a means to distinguish them from the harmful F. tularensis.
Despite this, the extensive breadth
of the
new study allowed the researchers to identify several genetic
markers underlying the fruit size increases, which is great news for breeders who might want to further increase the apple's girth.
Now that they have shown that this approach works at this level
of mapping detail, the Stanford group says it is working to make a
new map that has 30,000
markers spaced about 100,000 bases apart.
Researchers at Stanford University School
of Medicine have identified several
new biological
markers to measure the progression
of the inherited neurodegenerative disorder Huntington's disease (HD).
Most
of the scientific evidence in recent years had been gleaned from the bones
of members
of past civilizations in both the Old and
New worlds; bones were considered credible
markers since chronic syphilis causes skeletal lesions.
«These lung breakdown products have never been identified in TB before, and have the potential to be used as
new markers to identify patients with TB and monitor the effect
of new treatments on lung damage.
The goal is to identify
new disease diagnostic
markers and develop
new therapies, according to the company's head
of R&D in China, Andreas Tschirky, and chief scientific officer Li Chen.
The
new method for replicating genetic
markers, SNPs via MPS, were found to be successful in identifying the ancestry
of a suspect in most tests in the laboratory, which can provide another avenue for testing degraded DNA samples.
Zalasiewicz now thinks he's found the perfect
marker for the Anthropocene, or the
new epoch
of humans, so dubbed for Homo sapiens's world - changing impacts.
«This opens a
new door in identifying biological
markers for dementia since we might consider using the brain's processing
of speech sounds as a
new way to detect the disease earlier,» says Dr. Claude Alain, the study's senior author and senior scientist at Baycrest's Rotman Research Institute (RRI) and professor at the University
of Toronto's psychology department.
Now the residue from all the oil and coal burned to power modern civilization may provide the best
marker for the start
of a
new geologic epoch that highlights Homo sapiens's world - changing impact, known as the Anthropocene, or «
new age
of humans.»
Published in The Journals
of Gerontology, Series A: Biological Sciences and Medical Sciences, the
new study found that older patients with delirium had significantly elevated levels
of the inflammatory
marker interleukin - 6 (IL - 6) two days after surgery and also identified elevated levels
of interleukin 2 (IL - 2) in delirious patients.
«The significance
of this finding gives us a tentative approach to target this
marker and could lead to
new therapies for this subtype
of myeloma.»
University Professor
of Applied Physics Stephen Arnold and his team at the
New York University Tandon School
of Engineering have made a discovery that could lead to Star Trek - like biosensor devices capable
of flagging the barest presence in blood
of a specific virus or antibody, or protein
marker for a specific cancer; or sniffing out airborne chemical warfare agents while they are still far below toxic levels.
Researchers found less evidence for the formation
of new blood vessels and fewer protein
markers that signal neuroplasticity, or the brain's ability to make
new connections between neurons.
In a meta - analysis
of studies that linked genetic
markers to cultural heritage in North and Central America, Iceland, Australia, Africa and
New Guinea, they found that only Y - chromosome DNA reflected the cultural origins
of the local language.
By tracking these two major
markers, Treangen and Rocha calculated that the prokaryotes they studied acquired between 88 and 98 percent
of new genes through horizontal transfer.
These
new markers and tests could also be used to assist in treating drug dependence, in determining appropriate therapeutic levels
of medical marijuana, and for monitoring women who want to stop using cannabinoids during pregnancy.
Whilst the immune response to TBM sets up some
of the damage, this
new research suggests that
markers of ongoing neuronal injury are more predictive
of disease severity than
markers of immune response.
New markers suggested include total mass
of hemoglobin, altered expression
of genes related to red blood cell metabolism, ironomics, storage lesions, and the presence
of plasticizers from blood bags in athlete urine samples.
For the
new study, which is published today in the Proceedings
of the Royal Society B, Bowman and his colleagues collected samples from 38 L. mariae palms in Palm Valley and 100 L. rigida palms in the Roper, Nicholson, and Gregory rivers and compared the microsatellite
markers.
This analytical tool must thus be continuously refined and correlated with the introduction
of new markers.»
There has been a lack
of reliable
markers, early indicators and risk factors associated with pancreatic cancer, but this
new way
of differentiating between healthy and malignant tissue offers hope for earlier diagnosis and treatment.»
Our results pointed to three
new genetic
markers for FECD and confirmed the vital role
of a previously known
marker even among those who did not have a previously known family history
of the disease.
«Our research translates this technological development over to the biosciences and offers the possibility
of a
new biomedical diagnostics technique capable
of detecting the presence
of even a single cancer
marker molecule.»
A
new study indicates that, at least for most major groups in the United States, self - identified ethnicity corresponds closely with what genetic
markers reveal, suggesting that race can be a useful guide to at least some aspects
of biology.