The adult worms live in the heart and major blood vessels where they reproduce to create
new microfilariae.
At approximately 5 to 7 months post-infection, if both adult females and males are present, they will mate and produce
new microfilariae.
In the skin the larvae mate and form so - called
new microfilaria, which then reach the dog's bloodstream.
Not exact matches
If a dog is bitten by the pregnant female mosquito, her
microfilariae are released into the circulatory system and they wait there for a
new mosquito to bite the dog again.
In this final stage, the
microfilariae migrates to the heart and out into the pulmonary arteries (if there is room) where it will mate, approximately 5 - 7 months after first entering the
new host.
Once in the bloodstream of the
new host, the
microfilariae will spend the next week or two developing into the next stage of development within the host's skin.
If a mosquito bites a dog whose blood is filled with
microfilaria, the mosquito will become a
new vector of the parasite, the
microfilaria of which turn into larvae inside the mosquito.
The problem with using the slow - kill technique to kill adult heartworms, experts say, is this: If there are
microfilariae in the infected dog that are resistant to the macrocyclic lactone drug used, those parasites will be transmitted to mosquitoes, potentially finding their way to a
new dog in which to reproduce, increasing the risk to all dogs in the area.
Approximately eight months after the invasion, cat heartworm begins to produce a
new crop of
microfilariae that will live in the cat's blood for about one month.
Earlier this year, I examined 29 young dogs presented to shelters for routine spay / neuter in Farmington and Aztec,
New Mexico and found episcleral granulomas with nematodes in 3 dogs and
microfilaria in a skin snip biopsy from one of the dogs with episcleral nematodes.
However, in stage one the disease has not yet progressed to the point where the heartworms will have produced a
new generation of
microfilariae and dog's body will not yet have produced antigens in an amount sufficient for detection.
The
newer products such as the selamectin and moxidectin products do not clear
microfilaria well enough to be used to treat an active infection so right now the ivermectin - based products seem to be the best for this use.
When that mosquito bites another animal, the matured
microfilaria larva, are then passed on to the
new animal during the bite.