Sentences with phrase «new model animal»

Not exact matches

Studies show that these models can accurately predict the ways that new drugs will react in the human body and replace the use of animals in exploratory research and many standard drug tests.

Initial studies conducted by Christine Radtke, new Professor for Plastic and Reconstructive Surgery at MedUni Vienna / Vienna General Hospital, have shown in an animal model that the threads have great potential for nerve and tissue repair.

New research from an international group led by Min Zhao, professor of ophthalmology and of dermatology at the University of California, Davis, shows that, in animal models of diabetes, slow healing is associated with weaker electrical currents in wounds.

We do not cover developments of interest only to specialists, such as new animal models of a disease or the opening of new science research centres.

Researchers at the University of Missouri developed a new molecule in April 2014 that was found to be highly effective in animal models exhibiting SMA.

The findings are interesting, says René Hen, a neuroscientist who studies depression at Columbia University in New York, but «animal models of depression are very imperfect.»

«Cerebellar interactions with the frontal cortex in cognitive processes has never been shown before in animal models,» says Parker, UI assistant professor of psychiatry and the first faculty hire of the new Iowa Neuroscience Institute.

Scientists at Duke Health who developed the new model also discovered that targeting a brain receptor in mice with this type of autism could ease repetitive behaviors and improve learning in some animals.

In the lab, researchers will try to re-create the Thai results in monkeys to validate a new animal model using multiple low doses.

New experimental models based on three - dimensional reconstructions of human skin are helping to reduce chemical testing on live animals, but can not yet replace animals altogether

Senior author Byungkook Lim, an assistant professor in the Neurobiology Section, said the results require much more study and evaluation to be applied to humans with depression, but the new research in animal models provides solid grounding.

New research from McLean Hospital neuroscientists shows in an animal model that being bullied can have long - term, dramatic effects on sleep and other circadian rhythm - related functions, symptoms that are characteristic of clinical depression and other stress - induced mental illnesses.

A new study by scientists from the Florida campus of The Scripps Research Institute (TSRI) found no evidence of increased aggressive behavior toward strangers in an animal model of the condition.

A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis.

Using a new technique to deliver gene - therapy - like intervention directly where it's needed, researchers at Thomas Jefferson University successfully increased or decreased the muscle tone of the anal sphincter in appropriate animal models.

The scientists tested the new compound using a mouse model of TB and found that substituting R207910 for one of three antibiotics in a treatment cocktail significantly reduced the time required to clear the animals» lungs of bacteria.

Weaver studied the animal models for as long as 100 days, and found that the islet clusters transplanted with the hydrogel and VEGF developed many blood vessels and engrafted into their new locations.

Although the drug levodopa can relieve some symptoms, there is no cure — intensifying the pressure to find an animal model that can help clarify the pathological processes underlying human PD and find new medications to treat the pathology and / or relieve symptoms.

A promising new avenue for treating hepatitis B has been reported by researchers at Hiroshima University who have developed a new animal model of the disease.

The journal provides cutting - edge research including results from animal models that are likely to apply to patients, studies in human tissue that provide new information about therapies or disease, and innovative reports of drug discovery and development.

With the advent of new gene editing techniques, some less common animal models such as octopuses may find their way into scientists» toolkits.

They also stopped making new brain cells, something that has also been seen in other animal models of depression.

«The role of IL - 2 in delirium is a new finding and is particularly interesting since it was reported to induce blood - brain barrier dysfunction in animal models,» she added.

Young scientists trying to establish new animal models are also trying to establish their careers.

New animal models are now pointing to answers.

He took his prior work and expertise in the area of gastrointestinal motility and applied it to a new animal model, the zebra fish, to show that he could do what he proposed to do and then added a new hook to get it funded.

And several attempts to carve a new target from a family of enzymes called p38 kinases have also failed, despite favorable results in animal models.

In the new study, Professor Pisani and colleagues used cutting edge statistical techniques (Posterior Predictive Analyses) to test whether the evolutionary models routinely used in phylogenetics can adequately describe the genomic datasets used to study early animal evolution.

She kept feeding the new data into mathematical models that factored in the animals» age, migration patterns and disease prevalence in the population, among other things.

Now, a trio of studies in the July issue of Nature Medicine opens new avenues for plaque research by presenting a new animal model for plaque formation, a diagnostic tool for spotting them, and a possible way to break them down.

Importantly, the development of a new animal model for Dravet syndrome based on reduced CHD2 expression might help to find effective treatments that could improve the lives of thousands of people suffering from Dravet syndrome and perhaps other genetic epilepsies.»

«The big question about why we mammals affiliate with one potential partner versus another finally has a handle we can use in a small animal model,» says Lucy Brown at the Albert Einstein College of Medicine in New York.

Hope Mirendil, an alumna of the TSRI graduate program and first author of the new study, spearheaded the effort to develop the first - ever animal model of fetal cerebral hemorrhage.

In the new study, the Salk scientists used a mouse model of autism — an inbred strain of mouse previously found to display autism - like symptoms — to ask whether lowering the level of dicarbonyl methylglyoxal (a common byproduct of sugar metabolism) could alleviate symptoms of autism in the animals.

The researchers hope these findings will aid in developing new treatments by using animal models that more closely represent the types of mutations apparent in the vast majority of patients with enchrondromas.

«Since it's quite difficult to track microbial exposure on a daily basis, especially with humans — who move around a lot — we're exploring new animal models to see if we can ask the same questions we would about humans and get answers in more rigorous, controlled ways,» Gilbert said.

«Zebrafish brain repair following concussion: New model enables study of animal's remarkable ability to regenerate injured brain tissue.»

«We have demonstrated for the first time in an animal model that maternal use of a class of antidepressants called selective serotonin reuptake inhibitors, or SSRIs, resulted in increased fat accumulation and inflammation in the liver of the adult offspring, raising new concerns about the long - term metabolic complications in children born to women who take SSRI antidepressants during pregnancy,» says PhD student Nicole De Long, who presented this research on June 22nd at the joint meeting of the International Society of Endocrinology and The Endocrine Society.

«With further development, the new microendoscope could be used to image neuron activity in previously inaccessible parts of the brain such as the visual cortex of primate animal models,» said Ohayon.

The journal's home page explains that translational medicine «builds on basic research advances — studies of biological processes using cell cultures, for example, or animal models — and uses them to develop new therapies or medical procedures.»

Our studies have improved our understanding of the basic biology underlying MMA, created a novel animal model for testing interventions and, now, led us to the promise of a new therapy.»

By using new techniques based on computerised X-ray micro-tomography (CT scan) and digital three - dimensional modelling, Benoit found that the maxillary canal of therapsids, a bony tube in the snout of the animal that houses the trigeminal nerve, is shorter in therapsids than in reptiles.

With this in mind, Ian Lipkin and Amit Kapoorm, both at Columbia University in New York, set out to find a smaller animal that could serve as a model for hepatitis C.

«Given the key similarities to human infections, a marmoset model of Zika may be useful for testing of new drug and vaccines,» said Texas Biomedical Research Institute virologist Jean Patterson, Ph.D. «Having an animal model of Zika infection to study may help us identify places where we might be able to block transmission.»

With chronically infected mice as their model, the researchers used a new technology called ATAC - seq to map the regulatory regions of the genome — the sections of DNA involved in switching genes on and off — in the animals» exhausted and functional CD8 + T cells.

Ko is quick to note that these new findings do not warrant radical dietary changes in people with Crohn's: More studies, including more refined genetic analyses of fatty acids and Crohn's and testing in animal models, are needed.

Importantly, these devices also will open up new approaches to drug development not possible with animal models today, such as personalized medicines and development of therapeutics for specific genetic subpopulations using chips created using cells from particular patients.»

In addition to identifying how the virus causes acute liver injury, the UNC team, along with colleagues at North Carolina State University, established a new animal model of infection with the virus.

The use of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and human tissue.

In past studies to develop a new animal model for the brain events that support motor development, neurophysiologist Martin Garwicz of Lund University in Sweden and his colleagues discovered that the schedules by which ferrets and rats acquire various motor skills, such as crawling and walking, are strikingly similar to each other; the progress simply happens faster for rats.