Many of the major
new outbreaks of disease, particularly in Africa, are so - called zoonotic infections, diseases that are transmitted to humans from animals.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability
of new and maturing programs; 2) our ability to perform our obligations under our
new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on
new and maturing programs; 5) our ability to accommodate, and the cost
of accommodating, announced increases in the build rates
of certain aircraft; 6) the effect on aircraft demand and build rates
of changing customer preferences for business aircraft, including the effect
of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result
of global economic uncertainty or otherwise; 8) the effect
of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution
of key milestones such as the receipt
of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation
of our announced acquisition
of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability
of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk
of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production
of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts
of terrorism; 14) any adverse impact on the demand for air travel or our operations from the
outbreak of diseases or epidemic or pandemic
outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact
of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition
of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect
of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect
of changes in tax law, such as the effect
of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations
of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect
of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability
of raw materials and purchased components; 23) our ability to recruit and retain a critical mass
of highly - skilled employees and our relationships with the unions representing many
of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment
of interest on, and principal
of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness
of any interest rate hedging programs; 28) the effectiveness
of our internal control over financial reporting; 29) the outcome or impact
of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition
of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result
of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks
of doing business internationally, including fluctuations in foreign current exchange rates, impositions
of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
The race concept has been criticized for being an imperfect measure
of pathogenic diversity, but it is still considered useful to describe host reaction and
new disease outbreaks [1].
Outbreak of diseases and the consequent feeling
of insecurity made many accept the
new religion.
A NATION - WIDE
outbreak of foot and mouth
disease (FMD) could strip more than $ 50 billion from Australia's livestock industry over 10 years, according to a
new costing model from the Australian Bureau
of Agricultural and Resource Economics and Sciences (ABARES).
New York City Mayor Bill de Blasio has signed legislation aimed at preventing future
outbreaks of Legionnaires»
Disease.
The mayor's initiative, known as «
New York City Safe» and funded with $ 22 million, comes as the administration is working to contain an
outbreak of Legionnaires»
Disease in the Bronx.
In an effort to convey cooperation and unity,
New York City Department
of Health and Mental Hygiene Commissioner Dr. Bassett and
New York State Commissioner
of Health Dr. Zucker issued an update on the
outbreak of Legionnaires»
disease in the Bronx.
In
New York City, the five cooling towers suspected of causing the outbreak were cleaned by July 29, before the disease had even peaked, and once that was completed, the number of new cases began to decli
New York City, the five cooling towers suspected
of causing the
outbreak were cleaned by July 29, before the
disease had even peaked, and once that was completed, the number
of new cases began to decli
new cases began to decline.
SOUTH BRONX — The death toll in the worst
outbreak of Legionnaires»
disease in
New York City history has risen to 12, and the number
of people infected has gone up to 113, Mayor Bill de Blasio announced at a press conference Monday afternoon.
At a press conference on Saturday, the mayor tried to reassure
New Yorkers that the worst
of the
outbreak was over, saying that the
disease had been contained.
As the South Bronx reels in what the city is calling the worst
outbreak of Legionnaire's
disease in
New York history, Gov. Andrew Cuomo's administration today announced that state and federal agencies were getting involved in the fight — which up until now has been in the hands
of Mayor Bill de Blasio and Health Commissioner Mary Bassett.
A day after Gov. Andrew Cuomo rolled out
new statewide rules for the cooling towers that spawned the deadly
outbreak of Legionnaires»
disease in the Bronx, Mayor Bill de Blasio signed off on the city's portion
of the «joint» regulations on the potentially infectious air conditioning units — declaring it a «huge undertaking» because no such controls ever existed before.
Following the worst
outbreak of Legionnaires»
disease in
New York City history, the City Council passed a bill this afternoon that will require all cooling towers to be registered with the Department
of Buildings.
LEGIONNAIRES» FALLOUT: Monday morning at City Hall, Mayor Bill de Blasio will hold a bill - signing ceremony, beginning at 10 a.m. (full details below), and then, around noon, «the Mayor, Speaker Melissa Mark - Viverito and elected officials will host a press conference to introduce
new legislation to reduce future risk
of Legionnaires»
disease, and provide an update on the containment
of the
outbreak,» according to the mayor's public schedule.
The serendipitous pursuit
of a rapid
outbreak of virulent tuberculosis shows how the
disease can be stopped in its tracks, according to a report in tomorrow's
New England Journal
of Medicine.
Spending on cholera goes mostly to contain
outbreaks in
new places, leaving hotspots as continued sources
of disease.
A
new expert guidance document for hospitals to use in preparing for and containing
outbreaks was published by the Society for Healthcare Epidemiology
of America, with the support
of the Centers for
Disease Control and Prevention.
They're creating powerful
new software that can predict, simulate and analyze a major
disease outbreak — all in the form
of an intuitive, multiplayer game.
Even Tea Partiers, though, may have become a bit complacent because
of movies like
Outbreak that show how an antiserum for any
new disease can be synthesized in a matter
of hours with no specialized knowledge by Cuba Gooding Jr..
Certain
disease outbreaks, including some
of the worst pandemics
of the 20th century, are linked to weather patterns in the Pacific Ocean, according to
new research.
Zika is not
new to the U.S. Even as early as 2007, when the mosquito - borne
disease had its first large
outbreak in the Pacific island nation
of Micronesia, the virus directly touched the U.S. — sickening one American traveler.
Wencui Han
of the Department
of Management Science and Systems at the University at Buffalo,
New York and colleagues, explain how in the last two decades criminal incidents such as shootings on campus, assaults and robberies, natural disasters including tornadoes, hurricanes and snow storms and
disease outbreaks have put students and staff at risk.
Aside from inflicting devastating natural disasters on often vulnerable communities, climate change can also spur
outbreaks of infectious
diseases like Zika, malaria and dengue fever, according to a
new study by researchers at the University
of Colorado Anschutz Medical Campus.
While tropical temperatures appear to contribute, historical
outbreaks of yellow fever and dengue in the United States as far north as
New England show that mosquitos can indeed carry and transmit
disease in more temperate climates during summer months.
The effect
of seasonality in pathogen transmission on vaccination strategies was investigated under several types
of disease scenarios, including an endemic case and a
new outbreak case.
The
outbreak in West Africa threatens the momentum
of the polio eradication campaign, which cut the number
of new polio cases worldwide from an estimated 350,000 in 1988 to only 784 in 2003 and wiped out the
disease in the Americas, the Western Pacific region, and Europe.
«This nanoformulation approach allows us to make vaccines against
new diseases in only seven days, allowing the potential to deal with sudden
outbreaks or make rapid modifications and improvements,» says Daniel Anderson, an associate professor in MIT's Department
of Chemical Engineering and a member
of MIT's Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science (IMES).
MIT engineers have developed a
new type
of easily customizable vaccine that can be manufactured in one week, allowing it to be rapidly deployed in response to
disease outbreaks.
A
new type
of easily customizable vaccine can be manufactured in one week, allowing it to be rapidly deployed in response to
disease outbreaks, say researchers.
A
new study suggests that an aggressive reef competitor — the Threespot Damselfish — may have impeded the recovery
of Caribbean long - spined sea urchin populations after a mysterious
disease outbreak caused a massive die - off
of these animals over three decades ago.
Potential
outbreaks of diseases such as Ebola and Lassa fever may be more accurately predicted thanks to a
new mathematical model developed by researchers at the University
of Cambridge.
Although this is not the first major health crisis that HealthMap has covered — the 2009 H1N1 flu pandemic was one
of its largest efforts — the Ebola
outbreak has pushed the site in
new directions in an effort to provide information for a variety
of institutions, including the WHO, the United Nations and the U.S. Centers for
Disease Control and Prevention.
The health facts presented by mass media in the midst
of a
disease outbreak are likely to influence what we remember about the
disease —
new research suggests that the same mass media coverage may also influence the facts that we forget.
These
new regulations required for the first time that WHO member countries report
disease outbreaks that might cross their borders and also stipulated that they provide WHO with scientific rationales if they independently take actions that impede traffic or trade, like restricting travel or banning the importation
of pigs.
At the same time, the
new outbreak puts public fears
of bioterrorism and ballooning biodefense budgets into perspective by reasserting the impact
of naturally occurring
diseases, says Marjorie Pollack, who is monitoring the
outbreak for ProMED, a worldwide electronic reporting system.
The United States has sufficient capacity for treating another
outbreak of the Ebola virus, but financial, staffing and resource challenges remain a hurdle for many hospitals and health systems attempting to maintain dedicated treatment centers for highly infectious
diseases, according to
new study released today.
Polio is back and close to home — this time in the Netherlands, where a
new outbreak has killed one baby and caused at least 22 cases
of the
disease.
The first
outbreak in Britain
of the bee
disease varroasis, now taking a hold in southwest England, has prompted the government to waive its lengthy vetting arrangements for the licensing
of new agrochemicals.
A cluster
of neurological
disease in
New England recalls an
outbreak of paralysis in Guam.
The study, published online Aug. 17 in the journal Applied and Environmental Microbiology, describes a
new method for tracking the geographic range
of this airborne insect pathogenic fungus from areas
of a
disease outbreak.
A
new service from the web giant warns
of flu
outbreaks as related searches increase in frequency - it could one day warn
of new infectious
diseases
In 2003, DNA sequencing at the Michael Smith Genome Sciences Centre in Toronto and at the Centers for
Disease Control in Atlanta showed that the virus causing an
outbreak of severe acute respiratory syndrome (SARS) in China was a
new variant
of coronavirus.
Speaking from temporary offices in Amman, Jordan, he told
New Scientist: «In a city with a six million population we are afraid not only
of the direct impact in terms
of wounded and dead, but also other aspects
of public health like
outbreaks of disease.»
Genomic data about individuals and groups might be consulted during
disease outbreaks, in planning for public health programs, or in developing
new or assessing existing public health policies; for instance, where are the hotspots for infection (and are these associated with specific pathogen or host genomics), where should vaccines be deployed most urgently, which therapies should be offered to which genomic populations, and where should treatment programs, isolation policies or public health control programs be implemented to halt the spread
of infections?
Close
disease surveillance and targeted use
of anti-viral drugs could be enough to keep a small
outbreak of avian flu from becoming the first influenza pandemic in 36 years, according to a
new...
(15 Nov 2012, University
of Oxford): A
new study has demonstrated how DNA sequencing techniques can map tuberculosis (TB)
outbreaks, allowing the spread
of disease to be tackled more quickly and effectively.
Joseph Rosen, a professor
of surgery at Dartmouth College's Geisel School
of Medicine and adjunct professor
of engineering at Dartmouth's Thayer School
of Engineering, describes the
new approach to vaccine development as «revolutionary,» because it could dramatically reduce the amount
of time needed to respond to
disease outbreak.
COMPARE is a large EU project with the intention to speed up the detection
of and response to
disease outbreaks among humans and animals worldwide through the use
of new genome technology.
tomato collected during a recent
outbreak of bacterial speck
disease in
New York.