Sentences with phrase «new populations of cells»

«We have identified two new populations of cells in the brain that potently regulate appetite,» says Alexander Nectow, first author of the paper, published in Cell on July 27.

Not exact matches

Sampling was conducted via a stratified dual frame probability sample of landline and cell phone telephone numbers (both from Survey Sampling International) from within New York State weighted to reflect known population patterns.
Sampling was conducted via a stratified dual frame probability sample provided by Survey Sampling International of landline and cell phone telephone numbers from within New York State weighted to reflect known population patterns.
In the new study, led by graduate student Steven Briscoe, the team found that other populations of neurons in the bird DVR share molecular signatures with neocortical intratelencephalic cells, or IT neurons.
The two articles illustrate that these solutions make it possible to create new and easily reprogrammable behaviours of cell populations.
In contrast to the conversion of alpha cells, which only concerns a small fraction of the alpha cell population, the new mechanism involving delta cell fate change is a more efficient way of offsetting the loss of beta cells and thus diabetes recovery.
If such a population of cells existed, women might be able to produce new eggs later in life.
The KU researcher said that new evidence suggests that cancer originates and progresses by a small population of cells known as cancer stem cells.
Although the new JNCI study did not analyze individual cell phone usage — preferring instead to take a broader look at the population at large — other research has examined subgroups of cell phone users to try to discern different trends among more frequent use.
«Young students of cognitive neuroscience are lucky to be in the midst of a new era where we have access to amazing new tools of science for eavesdropping on the population of cells with a superb temporal resolution,» Parvizi says.
New techniques have made it possible to study the arrangement and interconnections of entire populations of cells
Scientists have found some serious loot in that bemoaned organ, including a vigorous population of flexible stem cells that can be coaxed into acting as new cartilage or tendons for damaged joints.
«Computer - based classification of cells based on large population of cell images opens up new perspectives.
The use of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and human tissue.
Now a team of engineers at MIT has developed a new way to deliver such vaccines directly to the lymph nodes, where huge populations of immune cells reside: These vaccines hitch a ride to the lymph nodes by latching on to the protein albumin, found in the bloodstream.
Conservation work to defeat the disease has including removing infected individuals from the population and new research in Evolutionary Applications explains how this gives us a unique opportunity to understand how human selection alters the evolution of cancerous cells.
«Scientists identify a new population of regulatory T - cells
A team of researchers at the Massachusetts General Hospital and Harvard Medical School in Boston has developed technologies for precision measurement of cell migration speed before and applied the new tool to study the variations of migration speed in population of cancer cells.
«Those approaches take a long time, it is difficult to isolate a pure population, and the NPC - like cells are still transient,» says Zhongwei Li, a research associate in the Izpisua Belmonte lab and co-first author of the new paper.
A new study in Nature Genetics identifies a specific population of pluripotent embryonic stem cells that can reprogram to totipotent - like cells in culture.
Now Prof. Daniel Offen and Dr. Adi Shruster of Tel Aviv University's Sackler School of Medicine have discovered that by reestablishing a population of new cells in the part of the brain associated with behavior, some symptoms of Alzheimer's disease significantly decreased or were reversed altogether.
Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.
Researchers at the Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem — Inserm / AFM / UEVE), in collaboration with CNRS and Paris Descartes University, have recently developed a new approach to better control the differentiation of human pluripotent stem cells, and thus produce different populations of motor neurons from these cells in only 14 days.
The human influenza virus H1N1 that caused the 2009 flu pandemic, and H9N2, an avian influenza virus that is endemic in bird populations in Asia, are close cousins — close enough that they can swap genes if they find themselves in the same cell, resulting in new viruses that are a patchwork of the parent strains.
The new study from Tonegawa's group builds on previous research demonstrating that episodic memories are physically represented in populations of cells in parts of the hippocampus.
To devise a potential new therapy, the investigators engineered a population of neural stem cells to express a potent version of a gene called TRAIL, which codes for a molecule that activates cell - death - inducing receptors found only on the surface of cancer cells.
To devise a potential new therapy, the investigators engineered a population of bone marrow derived mesenchymal stem cells loaded with oncolytic herpes simplex virus (oHSV), which specifically kills dividing cancer cells while sparing normal cells.
Researchers at the Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem — Inserm / AFM / UEVE) have recently developed a new approach to produce different populations of motor neurons from these cells in only 14 days.
But the new study firmly establishes that some of these cells endure for many decades in some Medalists — offering clues to potential treatments for preserving and even restoring the crucial cell population, says George L. King, M.D., senior author on the paper, Joslin's chief scientific officer and head of the Dianne Nunnally Hoppes Laboratory for Diabetes Complications.
The center will develop new single - cell approaches that overcome limitations inherent in traditional techniques — which analyze bulk populations of cells, thereby obscuring individual cell behavior.
The ability to make pure populations of these cells within days rather than the weeks or months previously required is a key step toward clinically useful regenerative medicine — potentially allowing researchers to generate new beating heart cells to repair damage after a heart attack or to create cartilage or bone to reinvigorate creaky joints or heal from trauma.
But, it was known that when HIF - 1 normally activates signals in the body to build new vessels, one of the many types of cells recruited to the site of new vessel growth is a population of stem cells from the bone marrow, which are called bone marrow - derived angiogenic cells.
The overall goal of this research is to provide new insight into the function and dysfunction of human neural cell populations in aging and neurological disorders, such as LOAD, and to identify mechanisms and molecules that can be translated to developing and testing novel diagnostic tools and therapeutics.
The ability to quickly generate purified populations of specialized precursor cells has opened new doors to further study.
The center also develops new approaches that overcome inherent limitations in traditional techniques, which analyze bulk populations of cells, thereby obscuring individual cell behavior.
«This new understanding of the role played by scrawny may make it easier to expand stem cell populations in culture, and to direct stem cell differentiation in desired directions,» says Spradling.
A major new insight is the realization that different tumors of the same type may rely on entirely different tumor stem cell populations.
Unlike other studies on p53, however, which target cell populations that average many cells together, Dr. Lahav developed a new approach, quantifying p53 at high temporal resolution in single cells and taking into account that «individual cell decisions are crucial in the development and treatment of cancer.»
The patterns of these mutations suggest that sAML evolved from a clonal population of MDS cells that acquired new mutations along the way.
Today, analyzing and editing genomes, proteomes and metabolomes has become a standard for many model systems; imaging beyond the diffraction limit of light and new technologies for studying protein structures provide insights deeper than ever before; the characterization of large populations of cells or organisms brings unprecedented statistical power; and studying nearly all organisms of an ecosystems as a whole allows generating comprehensive models.
CAMBRIDGE, Mass. - When cut, a planarian flatworm can use a population of stem cells called neoblasts to regenerate new heads, new tails or even entire new organisms from a tiny fragment of its body.
This led researchers from the group of Joseph S. Anderson (University of California Davis, USA) to formulate a new strategy; the use of a combined anti-HIV and selection vector [5, 6] to enrich for modified HSPCs, to provide a pure and effective cell population for therapeutic purposes.
«Using a new technique, we were able for the first time to separate low - PSA and high - PSA prostate cancer cells, which led to the discovery of a low - PSA population of cancer stem cells that appears to be an important source of castration - resistant prostate cancer,» says Tang.
We might be able to use stem cells to produce lots of new sperm and eggs and fertilize them to grow their population.
Sorting breast cancer cells using a new reporter construct allows the interrogation of a highly pure population of cancer stem cells and may allow for the discovery of new therapeutic targets
Inventors at MUSC have identified a unique human CD4 + T cell population that expresses high levels of surface CD26, termed CD26high T cells, which mediate durable antitumor immunity in vivo, and have immediate clinical relevance for designing new vaccines and cellular therapies.
Advanced reproductive techniques such as artificial insemination, culturing of primordial germ cells for germ - line transmission, stem cell embryogenesis, and cloning offer an array of new ways to expand and even infuse lost and new genetic variability into at - risk wildlife populations.
New CFSE - based assay to determine susceptibility to lysis by cytotoxic T cells of leukemic precursor cells within a heterogeneous target cell population.
Developing novel tools to quantify gene expression in single cells As it has become increasingly apparent that gene expression in individual cells deviates significantly from the average behavior of cell populations, new methods that provide accurate integer counts of mRNA copy numbers in individual cells are needed.
The center will develop new approaches that overcome inherent limitations in traditional techniques, which analyze bulk populations of cells, thereby obscuring individual cell behavior.
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