Columbia researchers have uncovered
new roles for proteins of the electron transport chain that implicate them in utilization of phenazines.
As a basic researcher, he has been most interested in looking for ideas that point toward new directions in the field:
a new role for a protein or a new understanding of how cellular proteins drive the immune response.
Not exact matches
Stagljar and his colleagues also applied the
new technology, which they dubbed MaMTH (
for Mammalian - Membrane Two - Hybrid assay), to identify a
protein that plays a
role in the most common form of lung cancer called non-small cell lung cancer.
A
protein that transports the simple chemical choline plays a major
role in vesicle trafficking, ion homeostasis, and growth and development in plants, according to two
new studies publishing 28 December in the open - access journal PLOS Biology, by Dai - Yin Chao of the Shanghai Institutes
for Biological Sciences, China, and Sheng Luan of the University of California, Berkeley, USA, and co-workers.
Children with high everyday levels of a
protein released into the blood in response to infection are at greater risk of developing depression and psychosis in adulthood, according to
new research which suggests a
role for the immune system in mental illness.
The current study identified a
new role for a particular group of
proteins, known as RFX transcription factors, in the development and survival of the hair cells.
«
New role for fragile X
protein could offer clues
for treatment.»
Research from Rutgers Cancer Institute of
New Jersey shows that the RUNX2
protein, which regulates the transcription of genetic messages responsible
for the different functions of cells, may play a
role in melanoma cell growth and spread and could serve as a therapeutic target
for the disease.
Her earlier work suggested that a tolerance
for endotoxin is what protects children raised on farms, and this
new study provides strong support
for this
protein's
role in guarding against allergies.
Researchers from the University of Leeds and The Pirbright Institute identified a
new role for a small viral
protein — called 3B3 — revealing how these viruses can copy themselves efficiently.
«
New cytoplasmic
role for proteins linked to neurological diseases, cancers.»
Researchers at UT Southwestern Medical Center have identified a second
role for a class of RNA - binding
proteins, revealing
new insights about neurological diseases and conditions associated with this
protein such as autism, epilepsy, and certain types of cancer.
«The biochemical mechanisms of these
proteins have been known
for years from experiments involving purified
protein and DNA, and that's very important, but in this
new work we've clarified these
proteins»
roles in living cells,» said co-senior author Christopher P. Selby, PhD, research assistant professor of biochemistry and biophysics at UNC.
Researchers at the University of Michigan Health System have identified a
new way of triggering the
role of the muscle
protein dystrophin, which is found in the muscles used
for movement and in cardiac muscle cells.
However, the
new study does not have direct proof of a
role for the
protein in implantation, she says.
«Three - dimensional structural information derived from the data obtained at the ESRF was essential
for the interpretation of the work, as it led to a high - resolution structure of the
new active site and provided conclusive evidence of the
role of
protein re-organisation in the emergence of the
new function» explains Jose A. Gavira, corresponding author, from the University of Granada.
Now, results of a
new study by Johns Hopkins Kimmel Cancer Center scientists suggests a powerful
role for the
protein in normal breast cells, acting as a tumor suppressor that halts abnormal cell growth.
Juan Bonifacino's lab at the National Institute of Child Health and Human Development,
for one, had discovered the
role a certain
protein plays as asymptomatic infection progresses to AIDS but testing of a
new class of potential HIV medications had to be stopped due to the shutdown.
New work that focused on this nighttime growth found a
protein that is necessary
for it to occur and, surprisingly, the
role of this
protein was linked to the construction of the plant's cellular membranes.
The proteasome plays a key
role in the smooth running of a healthy cell, facilitating cell renewal and death — chopping up
proteins tagged
for destruction into short polypeptides which can then be converted to amino - acids and recycled
for use in building
new proteins.
«Possible
new explanation
for ALS: Researchers discover RNA - binding
proteins play important
role.»
Initially working on the development of processes
for the production of the
new proteins in Serono's portfolio, his
role has evolved into a more managerial one.
«Bacterial and host cell
proteins interact to regulate Chlamydia's «exit strategy»:
New research suggests major
role for calcium ion signaling in release of Chlamydia from infected cells.»
For the new study, the research team focused on activating an enzyme known as AMP - activated protein kinase, or AMPK, which — among other roles — stimulates the breakdown of glucose for ener
For the
new study, the research team focused on activating an enzyme known as AMP - activated
protein kinase, or AMPK, which — among other
roles — stimulates the breakdown of glucose
for ener
for energy.
Now, Dong et al. have investigated the consequences of Dab2 downregulation in a
new STEM CELLS Translational Medicine study, demonstrating a novel
role for calcium / calmodulin - dependent
protein kinase kinase - 1 (CAMKK1) in the modulation of MSC secreted factors and a potential exciting means to enhance MSC - based cardiac repair [2].
A
New Fluorescent Probe
for Protein Interactions More Proof of Outer Membrane Cytochrome
Role in Electron Transfer Scientists Show How Bacteria Move Electrons Across a Membrane
«The
new protein plays a key
role in the formation of adherens junctions of epithelial cells, and Listeria uses it
for its own infectious process.»
We investigate the
role of genes and
proteins in the onset of cancer, with the goal of identifying
new treatment targets
for this disease.
Scientists from the UNC School of Medicine have developed a
new tool
for studying a key process in cells called G -
protein signaling, which plays a central
role in the normal functioning of cells and can go awry to cause severe disease, including cancers.
Our scientists have also pointed the way to a
new therapeutic strategy
for multiple sclerosis and other neurological diseases by identifying that a blood
protein, fibrinogen, plays a causal
role in damaging the central nervous system.
«Our research on the
role of blood
proteins in brain functions has identified
new targets
for therapeutic intervention in multiple sclerosis and other neurological diseases,» said Dr. Akassoglou.
We have already discovered
new roles for some of these
proteins.
This work revealed
new roles for XBP - 1 in regulating signal transduction through the B cell receptor; in regulating the expression of important transcription factors in B cells; in maintaining proper lipid synthesis and
protein glycosylation in B cells; and in colonization of stimulated B cells into the bone marrow
for sustention of antibody production.
The information
role of DNA was further supported in 1952 when Alfred Hershey and Martha Chase demonstrated that to make
new viruses, a bacteriophage virus injected DNA, not
protein, into the host cell (see How Viruses Work
for more information).
Johnson and Cole Labs uncover a
new role for a tumor suppressor in DNA repair (11/15/16) Work from the Johnson lab previously showed that E2F1, a critical transcription factor target of the retinoblastoma (Rb) tumor suppressor
protein, localizes to sites of both UV and IR induced DNA damage in a phosphorylation dependent manner.
Scientists find a
new role for RNAi
protein Dicer in preventing collisions during DNA replication...
Wu says his lab will investigate the
role that localized
protein synthesis plays in the growth and connection of neurons — work that ultimately could lead to
new interventions
for conditions such as autism and Alzheimer's disease, which are associated with a dysregulation of localized
protein production.
The idea that increased TUT can play a vital
role in prompting
new growth has been influential in bodybuilding circles
for decades, although it wasn't taken too seriously until the appearance of a study called «Muscle time under tension during resistance exercise stimulates differential muscle
protein sub-fractional synthetic responses in men» was published in The Journal of Physiology in 2012, followed by a couple of other deeply flawed scientific reports.
Vitamin K plays a
role in bone development, helping your bone cells produce
proteins required
for the formation of
new mineralized bone tissue.
For example, one of the most important
roles of glutamic acid is donating itself to insure that
new muscle
protein construction occurs in your tissues.
Jawaharlal Nehru University,
New Delhi • India 2007 Intern — Department of Life Science Accomplished major research project focused on «the
role of PIG - P
protein in association with GPI - anchor biosynthesis pathway» at the graduate level
for University Grant Commission (UGC), India.