For example, when treating someone who had run afoul of the law, they would encourage the individual to see him - or herself as a person who has made mistakes rather than a felon.White and Epston grounded
this new therapeutic model in three main ideas.
Not exact matches
For now, Rashid's group has a list of candidate
therapeutic drugs that they'll test in their
new liver disease
models, something that may still prove useful to patients.
«
New model for hepatitis B helps identify potential new therapeutic approach.&raq
New model for hepatitis B helps identify potential
new therapeutic approach.&raq
new therapeutic approach.»
This
new technology offers two main advantages based on the use of molecular tools to manipulate the genome: firstly, working
models that had not existed up until now for the study of tumour biology and, secondly, their application will eventually allow for the study of
new therapeutic targets and therapies.
«And while the tumor
model we're now studying doesn't present targets for
new drugs, if we can discover the mechanism controlling that
model, it may yield
therapeutic drug targets.»
«Although this is basic scientific research using animal
models, these studies are shedding light on the molecular mechanisms that control male fertility, and are helping us to better understand the causes of many cases of infertility and enabling
new horizons to be opened up in the development of
therapeutic targets and strategies to combat it,» explained Dr Subirán.
The CUMC team is currently using the
new mouse
model to study signaling pathways in the brain that drive anorexic behavior, with the ultimate goal of identifying
therapeutic targets.
«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease
modelling, and they could offer an excellent platform for drug discovery and testing
new therapeutic targets for Alzheimer's disease in the future,» says Early Stage Researcher Minna Oksanen, the lead author of the study.
«Novel imaging
model helps reveal
new therapeutic target for pancreatic cancer: Antisense treatment in preclinical
models shows effectiveness against deadly tumors.»
In a
new study, published online June 6 in Nature, researchers at University of California San Diego School of Medicine and Moores Cancer Center, together with colleagues at Keio University, the University of Nebraska and Ionis Pharmaceuticals describe an innovative
new model that not only allowed them to track drug resistance in vivo, but also revealed a
new therapeutic target, which early testing suggests could provide a strategy to arrest pancreatic cancer growth.
Knowing that Notch governs vessel permeability makes it a candidate for
new drugs to treat cardiovascular diseases as well, and the team is also investigating the TMD as a potential
therapeutic agent itself, as cell
models that were exposed to leak - inducing inflammation displayed a dramatic reduction in leakage when they were engineered to express the TMD.
The study of these
new mouse
models means an advance in the knowledge of disease's development mechanisms and an opportunity to implement
new therapeutic strategies for patients.
New research shows that a bioactive compound called resolvin D - 1, injected as a
therapeutic dose, is able to limit this collateral damage in the kidneys, as tested in an animal
model.
«Our results in experimental
models of cancer suggest a
new therapeutic strategy based on inhibiting the microRNA machinery — or the Let - 7 microRNAs — specifically in the TAMs, which may unleash the power of mainstream immunotherapies, such as immune checkpoint inhibitors.»
Research teams are also developing ways to innovate the early drug - discovery process, including pioneering methods to rapidly identify drug targets and test them on laboratory
models and finding and testing
new therapeutic possibilities for already FDA - approved drugs.
The Microbiology Services Division at Porton Down, part of the National Infection Service directorate, has extensive high - containment laboratory facilities and rare capabilities to handle infectious organisms under the highest levels of containment, and the ability to work with in vivo
models to evaluate
new therapeutic interventions against these organisms.
In parallel to these functional pathological studies, we also demonstrated the pertinence of this
new disease - specific cell
model to identify
new therapeutic strategies.
These
models would be ideal platforms for identifying
new genetic treatments and validating potential
therapeutic options.
With the reference cell census data in hand, the research team is excited to conduct additional studies, including ones involving
models or human patients with gastrointestinal conditions — Crohn's disease, ulcerative colitis, gastrointestinal cancers, forms of food allergy, etc. — aimed at identifying changes in gene expression and epithelial structure and function that could reveal
new insights and opportunities for
therapeutic development.
Development of advanced preclinical
models are needed to further elucidate the complex mechanisms underlying asthma exacerbation and investigate
new therapeutic strategies.
Our collaborations with industry, government agencies, and academia focus on developing
new disease
models, elucidating
new therapeutic targets to develop treatments, safety testing on
new chemical entities, enabling better and safer design of
new consumer products, and
new applications in personalized healthcare.
PHENOMIN - ICS offers to generate genetically modified mouse
models on a high - throughput and large scale basis, and then to provide a first phenotyping characterisation, either standardised or more specific, for a better understanding of disease mechanisms and for the development of
new therapeutic treatments.
The system can be used by researchers as a
model to elucidate how viral infections contribute to exacerbations, gain insight into mechanism of action of drugs, and could potentially help identify
new therapeutic targets.
These unique experimental
models have been yielded mechanistic insight and potential
new therapeutic avenues.
This network funds pilot studies to expedite collaboration between the two groups, conduct
model organism - based functional studies of disease gene variants, and develop
new therapeutic strategies using
model organisms.
Identification of
new therapeutic applications for known drugs: Boston Children's investigators have developed and characterized a wide variety of preclinical assays and animal
models useful for identifying additional
therapeutic indications for safe compounds.
Dr. Jason Yustein's research interests include furthering the biological, molecular and genetic understanding of pediatric sarcomas, including osteosarcoma and Ewing's sarcoma, through the formation of novel
model systems that will lead to the discovery of
new therapeutic targets and subsequent development of
new treatment interventions.
Two
new NSG mouse
models allow immunological dissection of graft - versus - host disease (GVHD) responses and in vivo testing of
therapeutic agents targeting human CD4 T cells.
Hence we are initiating a
new paradigm for patient stratification based on
modelling multi-level patient phenotypes, which could beneficially influence patient outcomes by improving optimisation of
therapeutic strategies.
Moreover, alongside sharing these tools in group classes and one - on - one
therapeutic sessions, I'm interested in building a
new model through which both clients and practitioners can understand the healing process.
New Harbinger's books offer techniques drawn from the most well - researched, proven - effective
therapeutic models available, and are written by the foremost experts in psychology.
New approaches for creating the
therapeutic alliance: Solution - focused interviewing, motivational interviewing, and the medication interest
model: Psychiatric Clinics of North America Vol 30 (2) Jun 2007, 157 - 166.
«
New Hope Risings, Therapy and Wellness Center consists of experienced and compassionate behavioral health professionals offering an integrative and evidence - based
therapeutic model.
As play therapy is an emerging profession, it is essential that practitioners enhance its establishment by developing high quality research capability to create
new models of practice that serve to improve the quality of
therapeutic interventions for some of the most marginalised and troubled children.
Recent advances in our understanding of the behavior of complex natural systems via dynamic systems theory may shed
new light on the process of strategic family therapy and help us understand more fully the underlying purposes of the preferred
therapeutic stance and clinical interventions of this
model.