This opens the door to
new therapeutic options in the treatment of breast cancer, report the researchers in the scientific journal Science Translational Medicine.
Furthermore, this study also encourages the application of iPSC - MSCs as an
exciting new therapeutic option for a range of immunological disorders and suggests that further study of the secreted factors may allow the construction of efficient cell - free therapies in the near future.
However, while doctors strongly advice against unsupervised mixing of drugs, the synergy of two combined pharmaceuticals assessed in an experimental setting can reveal
completely new therapeutic options.
«We thought that if we could find out why these neurons have a natural resistance to ALS, we might be able to exploit this property and
develop new therapeutic options.»
The study
provides new therapeutic options to control metastasis and points out a strategy to be applied to cancer patients who also have cholesterol disorders.
In diabetes, we may be able to replace the defective beta cells, but regenerative medicine also
offers new therapeutic options for other organ defects and diseases.»
Apramycin and spectinomycin are of particular interest because they have minimal side effects, making them potentially
ideal new therapeutic options for CRE infection.
The concept for
new therapeutic options centers on findings made by Swati Bhattacharyya, PhD, research assistant professor in Medicine - Rheumatology, who identified the role that a specific protein plays in promoting fibrosis.
By providing additional data that suggests the potential therapeutic value of PTPN22 manipulation, the study may further the development
of new therapeutic options that inhibit LYP to reduce or prevent autoimmunity.
Currently available treatments including hydroxyurea, which is the only FDA approved drug for SCA, and hemopoietic stem cell transplantation all have significant limitations, so the search for
new therapeutic options continues.
Further experiments
identified new therapeutic options: Mice that are unable to produce Type - 1 interferon were protected against Listeria infection despite the migration of the gut bacteria into the liver, because their immune cells didn't produce high levels of Type - 1 interferon and IL - 10 after Listeria infection.
«Our study is a nice example of how the understanding of a disease on the molecular and cellular level results in
new therapeutic options.
«In the future, these results could also lead to
new therapeutic options for the treatment of other fibrotic diseases.»
According to the researchers, this give rise to hope for
new therapeutic options.