Researchers have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, offering
potential new treatment targets.
BREAKING DOWN MULTIPLE SCLEROSIS Taking narrow aim at the immune system isn't enough, so researchers are looking
for new treatment targets within nerve cells and even in the gut.
While such basic research can
suggest new treatment targets, the speakers noted that there are many obstacles before clinical treatment of brain disorders with optogenetics becomes a reality.
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New treatment targets cancers with particular genetic signature: Mutations in gene SETD2 make cancer cells vulnerable to drug inhibiting the protein WEE1.»
Scientists at MCG say a logical and
effective new treatment target for certain cancers is to block production of the chemical that initiates the call that allows tumor growth.
It may ultimately suggest revisions to diagnostic categories over the coming decades ---- and hopefully lead to
new treatments targeted on the basis of genetic factors and patterns of abnormal brain circuit activity, said Cuthbert.
«The neurotransmitter - based models we are currently using to treat depression are more than 40 years old, and we really
need new treatment targets.
The study, to be published online in Cell on Oct. 31, offers a new theory of cancer development and could open the door
for new treatment targets.
«Scientists unravel likely causes of blood vessel leakage in severe dengue: Dengue virus protein may disrupt protective lining of vessels, suggesting
potential new treatment targets.»
«At this time, when prescription opioid use and opioid overdoses are both major threats to our public health, it is important to identify
new treatment targets, such as epigenetic processes, that help to change the way that we do business in treating opioid use disorders,» said professor John Krystal, Editor of Biological Psychiatry.
«Identifying the molecular underpinnings of why some individuals are at - risk for developing anxiety and depression has the potential to identify
new treatment targets,» added Roseboom.
«We hope we will find that healthy function is restored as well, which could translate to
a new treatment target for this complex, disabling disease.»
«If these findings are confirmed in larger studies, they hold significant implications for
new treatment targets and open the door for more questions such as: should these patients be treated more aggressively with medications, cognitive rehabilitation, or even surgery to open up the artery,» said Lal.
The gene GT198, whether mutated by genetics and / or environmental factors, has strong potential as both as a way to diagnose breast cancer early and as
a new treatment target, said Dr. Lan Ko, cancer biologist in the Department of Pathology at the Medical College of Georgia at Augusta University and at the Georgia Cancer Center at AU.
The discovery of the histone mutation in 2012 has opened up a new line of research and a search for
new treatment targets.
The study, which was led by Sven Nelander, Uppsala University / SciLifeLab, and published in the journal EBioMedicine, illustrated how researchers in the future will be able to use large - scale data to find new disease mechanisms and identify
new treatment targets.
The findings, published today in the Journal of Affective Disorders, suggest that the causes of childhood - onset depression may be different from those of adult - onset depression, and could lead to
new treatments targeting the mechanisms which govern biological ageing.
This finding could open the door for
new treatment targets to help Parkinson's patients walk more easily.»