Sentences with phrase «new tumor blood vessels»

Not exact matches

In contrast, the biologic approach injects a genetically engineered protein designed to knock out a tumor's ability to produce new blood vessels, thereby cutting off its capacity to grow.

That's because hospitals are equipped with powerful new scanning machines primarily used to identify tumors, ballooning blood vessels, bone fractures, and a wide range of disorders in people.

Avastin binds to and shuts down a protein that stimulates new blood vessel formation around the tumor, cutting off its nutrient supply.

Patients received a tandem of lenalidomide, a drug that kills tumor cells, blocks blood vessel growth, and acts on the immune system, and dexamethasone, an anti-inflammatory agent, plus one of three new agents:

But a new study suggests that mutations in a tumor - suppressing gene can create a prime nesting ground that grows new blood vessels to feed the tumor.

Another found gene is linked to angiogenesis, the production of new blood vessels to support a tumor.

«We saw the formation of new blood vessels in tumors reduced by 70 percent,» she says.

Trebananib (formally known as AMG 386; Amgen) is a first - in - class peptide - Fc fusion protein (or peptibody) that targets angiogenesis (the growth of new blood vessels into cancerous tumors) by inhibiting the binding of both angiopoietin 1 and 2 to the Tie2 receptor.

«Breast - friendly, radiation - free alternative to mammogram in the making: New method identifies cancerous tumors by blood vessels structure.»

Studies have shown that stress might promote cancer indirectly by weakening the immune system's anti-tumor defense or by encouraging new tumor - feeding blood vessels to form.

Cancer cells and tumors at first rely on nearby blood vessels to get what they need to survive, but, as tumors grow, they need to form new vessels.

Due to the lack of oxygen in the cancer cells, VEGF - A (Vascular Endothelial Growth Factor) is formed and this promotes the formation of new blood vessels to supply the tumor.

This treatment inhibits the formation of new blood vessels that can help a tumor grow.

«If we could prevent development of the new blood vessels in the cancer tissue driven by these signals, tumor growth and metastasis can be slowed down or prevented.»

Earlier studies by Basu and others have shown that dopamine blocks the growth of new blood vessels in tumors by inhibiting the action of vascular endothelial growth factor - A (VEGF - A).

A new study led by scientists at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) suggests that dopamine — an inexpensive drug currently used to treat heart, vascular and kidney disorders — can be safely used in cancer treatment to curb the growth of blood vessels in tumors.

One goal of drug designers has been to prevent tumors from making new blood vessels, a process known as angiogenesis.

Researchers knew at the time that tumors can induce normal endothelial cells to form new blood vessels, a process called angiogenesis.

Like roads built to support a suburban development, new blood vessels form in and around tumors, sustaining the cancerous cells.

Judah Folkman demonstrates that tumors express factors that encourage new blood vessel formation, or angiogenesis, suggesting that targeting these factors to slow or halt angiogenesis could be a viable strategy for cancer treatment.

Some tumors may take advantage of the latter ability to create new blood vessels that support their ability to grow.

They discovered that PSMA is strongly expressed in the new blood vessels of all solid tumors.

Eventually, it could form the basis for a treatment to prevent a tumor from attracting new blood vessels.

VEGF normally promotes the growth of endothelial cells, which in turn helps build new blood vessels in tumors.

She is institutional principal investigator of the Phase I Consortium Study in New Agents in Neuroblastoma Treatment and directs NIH - funded work on effects of SPARC (secreted protein acidic and rich in cysteine, an amino acid) on neuroblastoma tumor growth and blood vessel formation.

More than 90 percent of patients with either high nm23, a protein that prevents the cancer from spreading, or low angiogenesis, minimal growth of new blood vessels to supply the budding tumor, were alive an average of 14 years after treatment, compared to only 70 percent of those with low nm23 or high vessel density.

Dangerous brain tumors hijack the brain's existing blood supply throughout their progression, by growing only within narrow potential spaces between and along the brain's thousands of small blood vessels, new research shows for the first time.

The growth of new blood vessels tends to occur quite early for most cancers; even small tumors found via mammogram frequently have a high microvessel count (MVC).

Inhibition of FABP4 also reduced tumor growth and the ability of tumors to generate new blood vessels.

For example, proteins related to angiogenesis, the process through which new blood vessels form to ensure supply of oxygen and nutrients to a tissue such as a tumor, are found to be clearly associated to clinical outcome in HPV - positive samples.

Recent studies have shown that curcumin can reduce growth of new blood vessels in tumors and metastasis and basically help kill off cancerous cells.

The chronically stressed mice had decreased immune function and experienced tumor development significantly earlier than the non-stressed mice.16 Other mouse studies of ovarian cancer showed that chronic stress resulted in increased cancer growth as well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risk.

VEGF stimulates the growth of new blood vessels, and without a new supply of blood a cancer tumor can't grow much larger than a dot the size of the period at the end of this sentence.

Red clover (Trifolium pratense) contains genistein, an anticancer compound that prevents new blood vessels from forming with in a tumor.

They also act aggressively against cancer by preventing cancer cell proliferation, inducing apoptosis — or cancer cell «suicide» — and inhibiting the formation of new blood vessels that nourish tumor growth.

Lycopene which is a cancer inhibitor through inhibition of angiogenisis — the growth of new blood vessels to supply the cancer tumor with blood.

This disease - fighting nutrient can slow the growth and development of new blood vessels that nourish tumors, increase a type of programmed cancer cell death known as apoptosis and reduce the proliferation of new cancer cells.

A component of green tea called epigallocatechin gallate (ECCG) is a powerful antioxidant that is believed to suppress the growth of new blood vessels in tumors.

This is bad for cancer because it allows tumors to grow new blood vessels.

Not only can phytates block the formation of new blood vessels that may be feeding tumors, they can disrupt pre-formed capillary tubes, indicating that phytates may not only help blockade tumors, but actively cut off existing supply lines.

And many phytonutrients may help block the formation of new blood vessels that feed tumors, and others appear to defend against toxic invaders.

Malignant adrenal cancers may spread through the body by invading the adjacent blood vessels and seeding new tumors in body cavities and other organs.