Sentences with phrase «new type of immune cell»

A few years ago, MS researchers were focused on a new type of immune cell called the Th - 17 cell, which appeared to be a key player in driving the neuronal damage in MS. Because Th - 17 cells produce the cytokine IL - 17, researchers likewise thought this chemical was essential to the disease.

Not exact matches

The new findings build on prior research from the Dhodapkar lab demonstrating that patients with Gaucher disease, an inherited lipid storage disorder, have a significant increased risk for developing myeloma; and the discovery of a subset of lipid - reactive immune cells, called type II NKT - TFH, that promote the development of plasma cells.

It is the stuff of dreams for flu scientists, but it could be within reach if a new type of vaccine that elicits an immune response from white blood cells is combined with traditional vaccines.

The drug's mechanism of action was entirely new: Instead of attacking cancer cells (like chemo), or indiscriminately revving up the immune system (like IL - 2), ipilimumab blocked a single receptor on one type of immune cell.

New technologies are coming to the fore that allow interrogation of the types of cells interacting with tumors, in particular providing intelligence on the broad variety of complex associations between tumor cells and the immune system.

In a report on their experiments, published April 2017 in the Proceedings of The National Academy of Sciences, the researchers say they found evidence that microglia, a cell type found in most vertebrae innate immune systems, affect the Müller glia's regenerative response and can be harnessed to accelerate the growth of new tissue in the retina.

Researchers developed a new type of cell transplantation to treat mice mimicking a rare lung disease that one day could be used to treat this and other human lung diseases caused by dysfunctional immune cells.

To help the new organ withstand the assault from the recipient's natural defenses, doctors developed tissue type matching, a technique to determine if the chemistry of the donor's immune system, defined by antigens on the surface of cells, was similar to that of the recipient's.

The new NYU Langone study revolves around the ability of immune cells to «decide» which cell types to become based on the type of invader encountered — including macrophages that arrive first at the sites of infection.

«Blocking immune cell treats new type of age - related diabetes.»

Two teams of scientists suggest that activating immune cells in fat can convert the tissue from a type of fat that stores energy to one that burns it, opening up potential new therapies for obesity and diabetes.

In an article published in the January issue of Cancer Cell, the researchers describe how a new type of immunotherapy drug targeting the protein TIM - 3 works to stimulate the immune system.

«Developing a new vaccination strategy against AIDS: The type of vaccine administered and the activation of the body's own immune cells influence the vaccine protection.»

In a new study published in Nature Neuroscience this week, researchers in the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital (BWH) investigate how genetic risk factors for Alzheimer's disease may influence a key type of immune cell.

Further experiments identified new therapeutic options: Mice that are unable to produce Type - 1 interferon were protected against Listeria infection despite the migration of the gut bacteria into the liver, because their immune cells didn't produce high levels of Type - 1 interferon and IL - 10 after Listeria infection.

To regain function, connections from the brain to the spinal cord must regrow, different types of immune cells have to clear the injury site, and stem cells in the spinal cord need to generate new nerve cells, which then connect to the muscles.

Her aim is to understand, at the molecular level, the mechanisms that control communication between the brain, immune system, and blood vessels — with the ultimate goal of designing new therapies that slow, stop, or reverse the progression of a wide range of neurological disorders, such as MS. Recently, Dr. Akassoglou's lab identified how microglia — a type of immune cell that acts as the brain's first line of defense — are activated when fibrinogen enters the brain or spinal cord.

For instance, the team uncovered a new type of chemical - sensing tuft cell (which helps alert the immune system to infection or other forms of injury) that displayed markers previously thought to be exclusive to immune cells and which may help sound the alarm about allergens and invading parasites.

Today, Rudensky, a Howard Hughes Medical Institute Investigator and professor of immunology at Sloan - Kettering Institute in New York City, counts among the world's foremost immunologists for his discoveries on the molecular architecture of a type of immune cell implicated in autoimmune disorders, inflammatory disease, and cancer.

The new study found that the level to which the immune systems of mice tolerated H. hepaticus is determined by the interplay of two types of T cells, which control whether the immune response to a microbe amplifies.

But novel genomic tools are beginning to reveal new, rare cell types as well as unexpected variability and plasticity within groups upending the traditional view of immune cells assigned to the same category as unvarying entities that behave in a constant manner.

11/6/2007 UCSD Researchers Discover Inflammation, Not Obesity, Cause of Insulin Resistance Findings may have important potential for new drug discoveries in fight against Type 2 diabetes Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation provoked by immune cells called macrop... More...

The new study extends these discoveries to a different type of immune cell.

For decades, scientists have been seeking a new type of vaccine that activates another player in the immune system called a T cell to fight off infections within different organs.

Kidney cancer — also called renal cell cancer — is one of the major types of cancer for which new immune - based cancer treatments are currently in development.