Sentences with phrase «new use of these stem cells»

We are encouraged by the new use of these stem cells to rapidly identify new treatments,» says co-senior author Dr. Jeffrey Rothstein, Director of the Brain Science Institute and the Robert Packard Center for ALS research at Johns Hopkins University.

Not exact matches

Using the gene - editing tool CRISPR - Cas9 to turn off certain genes in a mouse zygote as well as other new techniques to enrich the pluripotent stem cells of a rat, the group managed to grow various rat organs (a pancreas, heart, and eyes) in a mouse embryo.

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This includes a stem cell research centre, a network of drug discovery institutes and a # 20 million global clinical development fund dedicated to supporting Phase I and II clinical trials; and a # 2 million collaboration between University of Cambridge and University College London that will use donated cells from people with Alzheimer's to test potential new treatments

According to Science Daily, Dr. Nagy, senior investigator at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital, there is a «new method of generating stem cells that does not require embryos as starting points and could be used to generate cells from many adult tissues such as a patient's own skin cells.»

Adult stem - cells are now being used to grow new body - parts that can be implanted with no risk of rejection, the latter being the single largest cause of organ rejection and subsequent death.

Just before Thanksgiving, news broke about a new stem - cell technique that could produce the equivalent of embryonic stem cells (ESCs) but without using or destroying human embryos.

The increasing use of in - vitro - fertilisation techniques, and the emergence of new possibilities involving human cloning, mixing of human and animal genetic elements, and the use of embryonic stem cells for research, among other things, brought the need for further teaching.

They discovered that the chemicals and radiation used to kill tumor cells damage the stem cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.

Working with Skeletal Biologists at Southampton General Hospital, Catarina is investigating new optical techniques to monitor the development of the cells, used in new regenerative medicine approaches — in this case, to create and grow cartilage from human stem cells.

Researchers at Rush University Medical Center are exploring a new therapy using stem cells to treat spinal cord injuries within the first 14 to 30 days of injury.

Researchers, led by Joshua Mayourian at the Icahn School of Medicine at Mount Sinai, used mathematical modeling to simulate electrical interactions between these stem cells and heart cells to develop insight into possible adverse effects, as well as to hypothesize new methods for reducing some potential risks of this therapy.

Realistic stem cell therapies to replace diseased or damaged tissue may still be years away, but researchers have uncovered a promising new use for these undifferentiated cells: they can be programmed to become patient - specific laboratory models of inherited liver disease.

The new rules state that stem cells can be used if they are part of a study approved by the federal government, or if the protocol has been approved by an Institutional Review Board (IRB) that provides ethical review for research involving human volunteers.

Hamilton announced the newest organ - on - chip innovation, which recreates an intestinal lining using patient - derived stem cells, created through a partnership between Emulate and Cedars - Sinai Board of Governors Regenerative Medicine Institute.

Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and Center for Duchenne Muscular Dystrophy at UCLA have developed a new approach that could eventually be used to treat Duchenne muscular dystrophy.

These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast cancer and advances in the use of gene therapy, despite some setbacks; continuing progress in research on stem cells; the emergence of treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.

The Champalimaud Center for Translation Eye Research (C - TRACER), part of the LV Prasad Eye Institute in Hyderabad, India, will continue research begun by LV Prasad scientists, who use eye stem cells from living adults to grow new cells that are then implanted into damaged eyes.

The continued marketing and use of experimental stem cell - based interventions inside and outside the United States is problematic and unsustainable, according to a new paper by science policy and bioethics experts at Rice University's Baker Institute for Public Policy and Wake Forest University.

The distribution of fluorescent daughter cells can be used to create a mathematical model of blood formation, which can provide new insights into the behavior of stem cells.

The new method, described in the journal Stem Cells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem ceStem Cells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem cCells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem ccells and muscle progenitors directly from human pluripotent stem cestem cellscells.

«With the rise of new and unproven stem cell treatments, the NFL faces a daunting task of trying to better understand and regulate the use of these therapies in order to protect the health of its players,» said Kirstin Matthews, the Baker Institute fellow in science and technology policy and an expert on ethical and policy issues related to biomedical research and development.

The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.

Using next - generation sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate in Mitchum's lab, made a remarkable new discovery — nematodes possess the ability to produce a second type of peptide that can effectively «take over» plant stem cells that are used to create vital pathways for the delivery of nutrients throughout the plant.

Whether mammals generate new eggs in adulthood using stem cells has been a source of scientific controversy.

Antibiotics are cheap and readily available and if in time the link between their use and the eradication of cancer stem cells can be proved, this work may be the first step towards a new avenue for cancer treatment.

A therapeutic screening center, headed by Lee Rubin at the Harvard Department of Stem Cell and Regenerative Biology, is dedicated to using induced pluripotent stem cells to find new drugs for genetic diseaStem Cell and Regenerative Biology, is dedicated to using induced pluripotent stem cells to find new drugs for genetic diseastem cells to find new drugs for genetic diseases.

Last January, the House of Representatives voted, 253 to 174, to pass a bill, H.R. 3, that would allow researchers to use leftover embryos from in vitro fertilization (IVF) clinics to create new lines of embryonic stem cells, and in April, the Senate passed its version of the bill.

The study, which was led by postdoc Gregor Pilz and PhD student Sara Bottes, used in vivo 2 - photon imaging and genetic labeling of neural stem cells in order to observe stem cell divisions as they happened, and to follow the maturation of new nerve cells for up to two months.

Mindful of public sensitivities, Daley opted to pursue experiments using what he considers the least controversial human materials to create new nonpresidential stem cell lines — poor quality embryos and oocytes that, in his words, «otherwise would have been disposed of as medical waste.»

But stem cell biologist and physician Michele De Luca of the University of Modena and Reggio Emilia in Italy and his colleagues have been developing a way to counteract an EB - causing mutation by inserting a new gene into the cells used for grafts.

«LEVER 3 - D is amazing, it opens new vistas for understanding the stem cell niche,» said Dr. Sally Temple, a cell biologist at the Neural Stem Cell Institute in Rensselaer, N.Y. who has been using Cohen's software, through the course of its development, as part of her stem cell research since 2stem cell niche,» said Dr. Sally Temple, a cell biologist at the Neural Stem Cell Institute in Rensselaer, N.Y. who has been using Cohen's software, through the course of its development, as part of her stem cell research since 2cell niche,» said Dr. Sally Temple, a cell biologist at the Neural Stem Cell Institute in Rensselaer, N.Y. who has been using Cohen's software, through the course of its development, as part of her stem cell research since 2cell biologist at the Neural Stem Cell Institute in Rensselaer, N.Y. who has been using Cohen's software, through the course of its development, as part of her stem cell research since 2Stem Cell Institute in Rensselaer, N.Y. who has been using Cohen's software, through the course of its development, as part of her stem cell research since 2Cell Institute in Rensselaer, N.Y. who has been using Cohen's software, through the course of its development, as part of her stem cell research since 2stem cell research since 2cell research since 2005.

«As researchers started using these cells more, it became clear that during the process of reprogramming to create stem cells the cell was also rejuvenated in other ways,» says Jerome Mertens, a postdoctoral research fellow and first author of the new paper.

Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).

The new approach builds on information gleaned from developmental studies of embryonic stem cells (see story # 16) and one day may be used to create healthy replacements for harmed or diseased tissue.

Applying a new method that is used mainly in stem - cell research and regenerative medicine, researchers from the Technical University of Munich have now devised a robust intestinal model for molecular research into incretin release in a test tube (in vitro).

A new study in mice published in The Journal of Neuroscience details a potential therapeutic strategy that uses stem cells to promote recovery of motor activity after spinal cord injury.

A new test may reveal which patients will respond to treatment for graft versus host disease (GVHD), an often life - threatening complication of stem cell transplants (SCT) used to treat leukemia and other blood disorders, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published online today in the journal Lancet Haematology and in print in the January issue.

Ultimately, the goal is to use stem cells of an individual patient and create a personalized model of their reproductive system to test new drugs for safety and effectiveness.

«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease modelling, and they could offer an excellent platform for drug discovery and testing new therapeutic targets for Alzheimer's disease in the future,» says Early Stage Researcher Minna Oksanen, the lead author of the study.

Lorenz Studer, a stem - cell biologist at the Memorial Sloan Kettering Cancer Center in New York City who has spent years characterizing such neurons ahead of his own planned clinical trials, says that «support is not very strong» for the use of precursor cells.

After two earlier published attempts that led to early - stage embryos but not confirmed embryonic stem cells, Mitalipov and colleagues took steps to preserve a protein complex believed to help primate eggs restructure transplanted DNA, and employed a new imaging system to observe the egg's chromosomes directly instead of by staining them or using ultraviolet light, which might damage DNA.

«This information yields new insights into how sperm stem cells function and develop under normal circumstances,» says the study's lead author Bradley Cairns, PhD, senior director of basic science at HCI and professor and chair of oncological sciences at the U of U. «We have built a very important framework we can now use to help us understand what happens when things go wrong, resulting in issues like infertility and cancer in men.»

So beginning in 2000, the University of Minnesota began a new approach: using stem cells from two umbilical cord blood sources, which increased the chances of engraftment in adults to 90 percent.

The achievement represents a new direction in the use of human pluripotent stem cells, which have the potential to develop into any of the tissues of the human body.

Ploegh envisions the technique being used to create a new type of personalized therapy in the future — your own cells could be isolated, used to create stem cells that differentiate into erythroblasts, genetically modified to carry a molecule, and reinjected into your body.

Theoretically, such stem cells can form any of the body's cell types and could be used in new treatments for Parkinson's disease, diabetes, multiple sclerosis, cardiac disease, and spinal cord injuries.

In a new study scheduled for publication in The Journal of Pediatrics, researchers evaluated the safety and feasibility of using stem cell therapies on very preterm infants to prevent or treat BPD.

A particular type of stem cell found in muscle can give rise to new muscle tissue, so a team led by geneticist Luis Garcia of Généthon, a nonprofit biotechnology firm in Évry, France, investigated whether these cells could be used to reverse the dystrophin problems.

With so much work needed in studying the nature of stem cells and using them to study disease processes, therapies based on ES cells seem very far down the line, noted Lorenz Studer of Memorial Sloan - Kettering Cancer Center in New York, who pointed out that so far there have only been two published papers on therapeutic cloning, both of them in mice.