Sentences with phrase «new vaccine target»
By examining blood plasma of two - year - olds exposed to the disease, researchers have discovered a new vaccine target: a protein recognized by the immune systems of malaria - resistant children.
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«That's further evidence that BamE may be a new vaccine target against N. gonorrhoeae,» Sikora said.
The new vaccine targets the body's type I interferon system.
discovery of new vaccine targets by innovative approaches that allow the identification of non-classical vaccine antigens like non-protein antigens and subdominant epitopes and novel protein candidates
Not exact matches
Beyond the payroll tax and charitable donation programs, Cuomo offered up ideas to reduce traffic congestion in New York City, expand availability of flu vaccines for children, impose restrictions on sex offenders, provide funding for an early voting program, ban synthetic marijuana sales and target physicians who engage in medical misconduct.
Another possible application for the new machine is generating peptides that could be used as personalized cancer vaccines targeting unique proteins found in individual patients» tumors.
By dissecting the heritage of these cells, we can find new targets to tackle a range of conditions including infectious diseases, cancers and immune disorders, and even make vaccines more effective.»
In addition, vaccine - makers that use eggs can not begin developing new vaccines that target new virus strains until the U.S. Centers for Disease Control and Prevention (CDC) creates a live - virus reference strain for these companies to work with, a process that could take several weeks.
«Key benefits of large - scale use of universal over conventional flu vaccines: Mathematical model reveals potential effects of new vaccines that target multiple flu strains.»
The genetic code also holds clues to Chlamydia's surface proteins, which Stephens says should give researchers new targets for vaccines, diagnostic tests, and drugs.
«CD55 also gives us a hook with which to search for new parasite proteins important for invasion, which could serve as vaccine targets.»
In Europe, which has yet to see sustained transmission in communities, four countries cut deals with GlaxoSmithKline to purchase more than 100 million doses of a vaccine that targets the new H1N1 virus.
«Our new work suggests that vaccines targeting either virus could be engineered to induce both T cell and antibody responses effective to protect people in these areas.»
«New clues to how a successful HIV vaccine could work: Sugar molecules on HIV envelope protein are likely target for future candidate vaccines.»
Such efforts could reveal more about how the parasite invades red blood cells and replicates inside cells, which could generate new drug and vaccine targets.
It can take up to a year to determine the function of a single gene, which has slowed efforts to develop new, more targeted drugs and vaccines.
The ability to design new protein nanostructures could have useful implications in targeted delivery of drugs, in vaccine development and in plasmonics — manipulating electromagnetic signals to guide light diffraction for information technologies, energy production or other uses.
But by eliminating the sugar molecule, the new mutation also affects «a key region in the virus that is targeted by the immune system,» Hensley adds, making the vaccine less effective.
Whereas earlier, unsuccessful cancer vaccines usually targeted a single distinctive cancer protein shared among patients, these new ones contain multiple mutated proteins, or «neoantigens,» that are specific to an individual patient's tumor.
New vaccines that targeted first one and later two strains of polio, rather than all three, were introduced and began to make real inroads.
These findings add an important and previously overlooked component to the causes of dengue vascular leak, identify a new potential target for dengue therapeutics, and support inclusion of NS1 in dengue vaccines.
Together, these new findings highlight NS1 as an instigator of dengue - associated vascular leak and thus pinpoint a potential target for dengue drugs and component for dengue vaccines.
Her work - published in December 2007 - revealed genes involved in drug resistance and in evading the immune system, giving researchers potential targets for new therapies and vaccines.
A study led by St. Jude Children's Research Hospital identifies new path to a universal influenza vaccine emphasizing production of broadly specific antibodies that target multiple flu viruses
«In addition, our method offers the potential to accelerate the development of new vaccines by allowing the efficient evaluation of candidate target antigens.»
These same models are used to develop new anti-cancer vaccines based on long peptide or DNA vaccination targeting the antigen to antigen presenting cells.
Additional uses include precise diagnosis of microbial infection, describing transmission patterns, understanding the genomics of emerging drug resistance and identifying targets for new therapeutics and vaccines.
We use our mammalian expression technologies to create panels of recombinant pathogen proteins that are then used to identify new subunit vaccine targets for infectious diseases.
While searching for new targets for malaria drugs and vaccines, a team including a Howard Hughes Medical Institute (HHMI) medical student fellow reached a fundamental insight about evolution:...
This step is essential for parasite transmission to humans and understanding the underlying mechanisms can help to identify new drug - and vaccine targets.
'» In all patients who were vaccinated, his team found tumor - targeting T cells, and he noted that in addition to augmenting pre-existing T cell responses, the vaccine also stimulated new T cell responses against tumors.
His team and their collaborators are currently mining the genome sequence for new targets for human vaccines and therapies.
By understanding erythrocyte invasion in depth, his group aims to identify molecular steps in the invasion process that could be targeted by new drugs or vaccines.
The paper reports that it could potentially form the base for a new universal influenza vaccine that could target all strains of the virus.
These results may provide new ways for vaccine researchers to target HIV and may influence the design of future HIV vaccines.
VAC2VAC is a new project in the EVI portfolio that is different from other EVI projects in that it is not targeting to develop a new vaccine.
Now, a new vaccine under development could deal another blow to the disease, lowering the number of deaths even further by targeting dozens of additional strains of S. pneumoniae, and anticipating future versions of the bacteria responsible for pneumococcal disease, which includes sepsis and meningitis.
The availability of a new and improved P. cynomolgi reference genome sequence will enable in - depth studies of this widely used model parasite, including investigations into dormant stages and the selection of new drug targets and vaccine candidates.
These could include targeted probiotic therapy, novel vaccines or vaccine strategies and new therapeutics to treat LRTI.
The findings should help scientists to better understand the immune system, including autoimmune diseases, as well as provide potential new targets for immunotherapy and vaccine design.
He has made several important contributions in this area including identifying a new strain of CHIKV virus, identification of host cellular targets of HIV accessory genes, new novel DNA vaccine approaches for HIV, CHIKV, RSV, Dengue, MERS and Zika among others.
Studies conducted and supported by NIAID have led to important new discoveries about the microbes that cause NTDs, the identification of targets for potential new drugs and vaccines, and the development of strategies for controlling organisms that transmit NTD - causing agents to humans.
In the new study, the team's experimental vaccine works by effectively misdirecting the immune system to fight off a more dangerous target than the allergen.
He is using lymphocyte receptors as targets for new therapies for lymphoma, and is currently conducting clinical trials of lymphoma vaccines.
Therefore the group: i) characterizes the specificity of these antibody responses to identify relevant targets for a vaccine; ii) developes new approaches to test antibody responses; and iii) adoptes the immunological analysis in preclinical (in rabbits and macaques) and clinical vaccines studies to identify predictive signatures for the development and prioritization of new HIV - 1 vaccine candidates.
NJTV - New Pancreatic Study May Offer Hope for the Future - November 17, 2011 CINJ Deputy Director Dr. Edmund Lattime and Co-Director of CINJ's Gastrointestinal - Hepatobiliary Oncology Program Dr. Elizabeth Poplin discuss early results to a unique clinical trial that uses vaccine therapy to target pancreatic cancer.
This new feline leukemia vaccine uses the VET JET transdermal vaccination system to target presentation of vaccine in the dermis, subcutaneous layer and muscle tissues, allowing rapid and comprehensive immunity.
The Society has a new low - cost Wellness and Vaccine clinic, offers discounted grooming services, food, and targeted spay / neuter and education programs to help pets and their owners every step of the way.