«This study is important, in part because we now have
a new xenograft model that will for the first time allow us to apply new biomarkers to better predict disease progression and test new therapeutics.»
Not exact matches
To overcome these problems, Min and his team developed a
new modality to visualize glucose uptake activity inside single cells based on stimulated Raman scattering (SRS) imaging, and demonstrated its use in live cancer cells, tumor
xenograft tissues, primary neurons and mouse brain tissues.
He developed
new techniques for transplant surgery, helped to make kidney transplantation viable and was one of the first researchers to try
xenografts — in the 1960s he placed baboon kidneys in six patients.
In a 1988 paper summarizing his findings, Fiebig concluded that
xenograft mice were wonderful models for broadly testing
new drugs against human tumors, but they «can not be used as a clinical routine method» for predicting patient treatment.1 The idea of using
xenograft mice as personal avatars for cancer patients was discarded.
AMSBIO announces the availability of two
new formulations of Basement Membrane Extract (BME) known as Cultrex BME 2 (organoid growth matrix) and Cultrex BME 3 (
xenograft / tumorgraft matrix).
NCI's efforts to develop
new laboratory models of human cancer includes vastly increasing the number of human cancer cell lines (grown as two - dimensional and three - dimensional cultures) and patient - derived tumor
xenografts.
Since starting her
new role as an investigator in the In Vivo Pharmacology group at Novartis Oncology, Bhang has been working on using the ClonTracer library to monitor clonal dynamics following drug treatment in cell line and primary tumor
xenograft models.
Therefore, our NSIN mice provide a
new platform for
xenograft mouse models in basic and translational research.