His current research activities include the implementation
of next generation sequencing technologies in a diagnostic setting and the use of this technology to better understand cancer etiology and treatment.
Loyola University Chicago's Genomics Facility is using an advanced technology
called next generation sequencing to assist a broad range of researchers studying the genetic make - up of organisms ranging from viruses to humans.
Dr. Li's research interests focus on machine learning, bioinformatics, and statistical data mining in large scale data in biomedical research, such
as next generation sequencing data (whole genome sequencing, RNA - seq, microarray data), in the file.
It also provides valuable information that may assist researchers in the development of genetic tests based
on next generation sequencing, and in the initiation of large intervention trials to assess the efficacy of orphan drugs.
We apply modern technologies
including next generation sequencing to help discover mechanisms and pathways relevant to human cardiovascular disease, such as atherosclerosis, atrial fibrillation, and HDL metabolism.
Natacha Gaitch and colleagues report an analysis done on six genes involved in pancreatitis or in ion transport into the pancreatic duct
by next generation sequencing in adult patients with cystic fibrosis (CF) and pancreatic sufficiency (PS) patients with two identified CF mutations.
Access to advanced high - throughput instruments
for next generation sequencing at SciLifeLab has enabled the very fast process of adding transcript data to the protein atlas.
Dr. Funari's research interests include developing new approaches for obtaining mycobiome profiles in human disease and the translation of
next generation sequencing applications into the clinic and personalized medicine.
However, a number of genes linked to neuropsychiatric diseases have no assigned function, and it is likely that the mutational landscape of these diseases will be complexified by the wealth of data generated
with next generation sequencing techniques.
You will find here the information about the opportunities of rare diseases research funding at the national level in «National RD funding initiatives» and «
Next generation sequencing facilities database» that groups sequencing platforms from Europe and Associated countires.
He is best known for developing one of the first protocols for
multiplex next generation sequencing of microRNAs, but is currently focused on new technologies for the sequencing and analysis of the immune system.
Join NSF AuthenTechnologies as we
discuss Next Generation Sequencing (NGS), chromatographic confirmation of botanical identity and the DNA Authenticated Verification program with help from NSF laboratory experts.
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Next generation sequencing tools were used to profile patients» tumors,» said Razelle Kurzrock, MD, director of the Center for Personalized Cancer Therapy at UC San Diego Moores Cancer Center.
In contrast, when the OncoFinder algorithm is applied to the data, a clear correlation
between next generation sequencing and microarray gene expression datasets was seen.
In 2011, she joined the institution's molecular diagnostics laboratory where she has been developing
translational next generation sequencing assays and bioinformatics workflows for the Molecular Tumor Profiling Lab of the Yale Cancer Center.
Using CDV strains collected in the Serengeti ecosystem from a range of carnivores between 1993 and 2012 and applying the latest state - of - the - art
molecular next generation sequencing techniques, the study discovered several CDV strains circulating in the ecosystem during this time, all belonging to a new genetic lineage of CDV termed «East Africa».
They report that a single 32 - node cluster can, «keep pace with the output of today's highest
volume next generation sequence operating at full capacity, completing analysis of 1 WGS every 30 minutes.»
Therefore, I am engaged in using, developing and combining new technologies, including: (1) super-resolution microscopy, (2) single molecule imaging, (3) genetic engineering, (4)
next generation sequencing approaches and (5) mathematical and biophysical modeling.
Bertout proposes to use new barcoding technologies she developed in the Bielas Lab to build
upon Next Generation Sequencing technologies and enable exquisitely sensitive cancer - specific mutation detection.
Glod J, Song M, Sharma A, Tyagi R, Rhodes RH, Weissmann DJ, Roychowdhury S, Khan A, Kane MP, Hirshfield K, Ganesan S, DiPaola RS, Rodriguez - Rodriguez
L. Next generation sequencing as an aid to diagnosis and treatment of an unusual pediatric brain cancer.